[PDF] Top 20 Effects on migration of breast cancer cells in 3D models upon MMP inhibition
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Effects on migration of breast cancer cells in 3D models upon MMP inhibition
... O cancro de mama foi, em 2012, a 5ª causa de morte por cancro no mundo [1]. A maioria destas mortes deve-se à metastização, facto que se reflete na taxa de sobrevida a 5 anos que em cancros localizados é de 98,6% ... See full document
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PTK6 promotes cancer migration and invasion in pancreatic cancer cells dependent on ERK signaling.
... silencing, in contrast, decreases them in pancreatic cancer ...The effects of PTK6 on cellular migration may vary among types of ...cacners. In the studies ... See full document
7
Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture.
... phenotype of these cells, PPARc, the top gene on this list (Table 1), has been reported to be a potent inducer of EMT in intestinal epithelial cells ...class of oral ... See full document
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Pharmacologic inhibition of MLK3 kinase activity blocks the in vitro migratory capacity of breast cancer cells but has no effect on breast cancer brain metastasis in a mouse xenograft model.
... Inhibition of MLK3 with URMC099 did not significantly change the growth rate of MDA-MB-231 and its subline, ...used in our in vivo studies - nor did it cause any obvious increase ... See full document
7
Potentiation of the Effect of Lonidamine by Quercetin in MCF-7 human breast cancer cells through downregulation of MMP-2/9 mRNA Expression
... activity in several cancers via interfering with ATP production in tumour ...efficacy of conventional chemotherapeutic agents (Nath et ...adverse effects have been observed in clinical ... See full document
12
Loss of myoferlin redirects breast cancer cell motility towards collective migration.
... effect of MYOF depletion on cell ...important 3D features of cancer cell migration including degradation of the tumor stroma and extracellular matrix via MMPs and the ... See full document
13
RANKL/RANK/MMP-1 molecular triad contributes to the metastatic phenotype of breast and prostate cancer cells in vitro.
... nature of bone metastasis results from a tumor-driven increased bone ...dysregulated in bone metastases, mostly via induction of RANKL by tumor-derived ...expression of RANKL, which induce ... See full document
9
Berberine suppresses migration of MCF-7 breast cancer cells through down-regulation of chemokine receptors
... overexpressed in different human malignancies including breast ...role in initiating and regulating tumor cell migration and metastasis ...overexpressed in cancer cells ... See full document
7
MiR-519d-3p suppresses invasion and migration of trophoblast cells via targeting MMP-2.
... metastasis in a range of pathological processes such as obesity [30], osteosarcoma [31], hepatocellular carcino- ma [20,21] and ovarian cancer [19]; however, a role for miR-519d in PE had not ... See full document
12
Antiproliferative effects of 1,25-dihydroxyvitamin D3 on breast cells - A mini review
... human breast cancer cells (9,10). The responsiveness of target cells to the hormone depends on the amount of VDR and many factors can modulate VDR ...sion in ... See full document
9
Estrogen induces Vav1 expression in human breast cancer cells.
... role in diverse cellular processes including calcium mobilization in T cells ...effect on NIH3T3 fibroblast cells ...profile of Vav1, which associates with several human tumor ... See full document
11
GLUT 5 is not over-expressed in breast cancer cells and patient breast cancer tissues.
... standard in positron emission tomography (PET) oncologic imaging since its introduction into the clinics several years ...FDG in the diagnosis of breast cancer using radio labeled ... See full document
8
Bioactivity-guided identification and cell signaling technology to delineate the lactate dehydrogenase A inhibition effects of Spatholobus suberectus on breast cancer.
... expression in a time- and dose- dependent ...tory effects on the activity and expression of LDH-A in MDA-MB- 231 cells than it did in MCF-7 cells, implying that ER ... See full document
12
Myrtus comunis and Eucalyptus camaldulensis cytotoxicity on breast cancer cells
... antioxidative effects (B u g a r i n, 2010; Tu b e r o s o, 2010), while its essential oil showed considerable antioxidant and antimuta- genic effects (M i m i c a - D u k i ć et ...source of natural ... See full document
9
New Learning Strategies in Deep Models for Breast Cancer Screening
... one of the main barriers to the use of more powerful models was the problem of internal covariate shift [ 108 ...problem of shifting distributions of the inputs to layers ... See full document
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Clinical applications of circulating tumour cells in breast cancer patients : based on a case report
... alterations of the targeted therapy [26]. In fact, discordances between the primary breast tumour and its metastasis have been shown to be as frequent as up to 40% for the HR and 10% for HER-2/neu, ... See full document
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Human breast cancer cells are redirected to mammary epithelial cells upon interaction with the regenerating mammary gland microenvironment in-vivo.
... population of human breast cancer cells was enriched for reprogrammable cancer cells, we selectively isolated breast cancer cells with surface markers (CD44) ... See full document
10
On-chip immunoelectrophoresis of extracellular vesicles released from human breast cancer cells.
... attention in the fields of cell biology and ...understanding of EVs and further exploration of their applications, the development of analytical methods for bio- logical nanovesicles ... See full document
13
Heparan sulfate mediates trastuzumab effect in breast cancer cells
... analysis of sulfated gly- cosaminoglycans (GAG) was performed essentially as de- scribed by ...60°C. Cells and medium aliquots were submitted to agarose gel electrophoresis in ...counted in a ... See full document
13
A membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cells.
... functions of SFKs involve the regu- lation of cell growth, survival, proliferation, differentiation, adhesion to matrix and a wide range of molecular signalling networks ...detected in MCF-7 ... See full document
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