[PDF] Top 20 Effects of vitamin K deficiency and its mechanisms in vertebrate's early development: zebrafish as a model

... reduction of the γ-carboxylation of coagulation factors in patients who are at risk of venous ...activity of other ...morbidity and mortality in pregnant women, being this ... See full document

... addressed in previous studies. To understand the processes underlying CHM in the zebrafish and to assess its usefulness as a model for human disease, we sought to further ... See full document

... efficiency of signal propagation in the modeled ...Watts and Strogatz [16] and has been since recognized as an important emergent property of a wide range of complex ...features ... See full document

... long-term effects is an important problem in radiation ...set of changes in the transcription profile that are associated with the long-term response to radiation ...performed in vivo ... See full document

... inflation and continuous enlargement are associated with marked transepithelial ion and fluid secretion into the cyst lumen via cystic fibrosis transmembrane conductance regulator ...degradation of ... See full document

... regulation in males and ...differences in susceptibility to oxidative stress or mitochondrial ...levels of hydrogen peroxide production and significantly lower levels of catalase ... See full document

... period of zebrafish (Schmidt et ...vulnerabilities and susceptibilities to anesthetics. Moreover, there is a gap in the knowledge of certain brain functions, as well as in the ... See full document

... and in an effort to achieve a better understanding of this behaviour, several attempts have been made to interfere with this robustly regulated ...alterations in protein synthesis and ... See full document

... behaviour and how these interactions occur in response to changes in the social environment is a major challenge in social ...fitness of other individuals, and have profound ... See full document

... cost-effective model species adequate for research, due to easy maintenance and ...use of this species is increasing mainly due to the information coming from genome sequencing, known target genes, ... See full document

... Different model organisms have been extensively used to study social cognitions, especially since the development of genetically based tools for studying the activity, anatomy and function ... See full document

... question in neuroscience is how the brain integrates sensory inputs and computes a behavioural ...optics and mathematical ...animal model with a relatively simple nervous system but with ... See full document

... The zebrafish, a small freshwater tropical fish, has become a powerful model system to study genetic mechanisms of vertebrate development and ...disease. Its ... See full document

... consumed in non- medical situations, including pregnancy (Rofael et ...ambiguous mechanisms involving apoptosis and NMDA receptors have been proposed for ketamine neurotoxicity (Liu et ...types ... See full document

... described in rats (10). Briefly, after anesthesia and adequate antiseptic preparation, a suprapubic midline incision of 4 cm was performed in order to expose the bladder ...urethra. In ... See full document

... set of zebrafish genes, we could not detect a statistically significant difference in the number of Pou5f1 and TcfLef binding sites (Figure ...regions of previously confirmed Wnt ... See full document

... metabolism of very low density ...uptake of vitamin K via endocytosis (Shearer and Newman ...One of the most studied functions of this vitamin is as a cofactor for ... See full document

... Vitamin K deficiency has been clearly documented in CF toddlers, preschool and schoolchildren as well as in aldolescents and adults [Montalembert et ...describing ... See full document

... immunotoxic effects of in vitro silica coated iron oxide nanomaterials functionalized with dithiocarbamate (IONM) exposure and its interference with mercury (Hg) co-exposure on European ... See full document

... Antinociceptive effects of Vit E or Vit C have been reported in earlier ...example, in the streptozotocin (STZ) model of diabetic neuropathy in rats, very high doses ... See full document