[PDF] Top 20 Expression of p53 protein in pituitary adenomas
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Expression of p53 protein in pituitary adenomas
... mutations of TP53, a tumor suppressor gene, are associ- ated with abnormal cell ...Although p53 expression is common in many human malignancies, p53 protein has seldom been ... See full document
5
Correlation between radiation dose and p53 protein expression levels in human lymphocytes
... aim of this research was to evaluate the relationship between p53 protein levels and absorbed doses from in vitro irradiated human ...samples of blood from 23 donors were irradiated ... See full document
8
Tumor suppressor p53 protein expression : prognostic significance in patients with lowrisk syndrome
... marrow biopsy sections from each patient were decalcified using 10% nitric acid and were paraffin embedded prior to immunohistochemical analysis. Then, the bone marrow sections were deparaffinized, hydrated, and washed ... See full document
6
Expression of p53 protein in Barrett’s adenocarcinoma and adenocarcinoma of the gastric cardia and antrum
... abnormalities in oeso- phageal and gastric adenocarcinomas, allelic losses on chromosome 17p and mutation of the p53 gene have been documented to be frequent events ...(9–11). p53 is a the tu- ... See full document
7
Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct ways.
... (IP) of myc-tagged proteins LacZ or MDM2-ALT1 or MDMX-ALT2 and also for the reciprocal IP of endogenous MDM2, MCF7 cells were transfected with the corresponding over-expression plasmids and 24 hours ... See full document
11
Análise imunohistoquímica da expressão das proteínas p53 e ki67 em adenomas colorretais
... aim of this study therefore is to evaluate the expression of p53 and Ki-67 proteins in colorectal adenomas, its relations with clinicpathological characteristics and assess the ... See full document
64
A Bmi1-miRNAs cross-talk modulates chemotherapy response to 5-fluorouracil in breast cancer cells.
... miR-200c expression has been linked with cancer progression and chemotherapy resistance via EMT process and CDCs regulation ...loss of miR-200c expression contribute to drug resistance ...implication ... See full document
10
Long-time treatment by low-dose N-acetyl-L-cysteine enhances proinflammatory cytokine expressions in LPS-stimulated macrophages.
... role of p53 as a tumor suppressor is the induction of cell cycle arrest of DNA-damaged cells to prevent proliferation of abnormal ...increased expression of p53 ... See full document
10
Sao Paulo Med. J. vol.115 número1
... ent of H ead and N eck Surgery of the A .C . C am argo H ospital in 1994 and ...fixed in C arnoy solution. A fter fixation, the m aterial w as em bedded in paraffin and 4 ~m thick ... See full document
7
Rev. Bras. Hematol. Hemoter. vol.27 número1
... mutation of the TP53 gene and inactivation of the p53 protein are the most common alterations observed in human ...tumors. In leukemias these alterations are not very frequent, ... See full document
2
p53 inactivation upregulates p73 expression through E2F-1 mediated transcription.
... apoptosis in cancer tissues, p73 overexpressing tumors appear to be of high grade ...overexpressed in cancer cells and what the function of overexpressed p73 is in breast cancers are ... See full document
10
Study of major genetic factors involved in pituitary tumorigenesis and their impact on clinical and biological characteristics of sporadic somatotropinomas and non-functioning pituitary adenomas
... of pituitary adenomas are typically 3% (35). Immunoex- pression of both markers, p53 and Ki-67, was not different between NFPA and ...somatotropinomas. In addi- tion, the level ... See full document
8
Arq. Gastroenterol. vol.49 número1
... result of an accumulation of genetic mutations that involve a different sequence: the mutation of the APC gene, DNA hypomethylation, activation of the K-ras protein, mutation of ... See full document
6
Wild type p53 transcriptionally represses the SALL2 transcription factor under genotoxic stress.
... deregulation in cancer, we searched for potential cancer-related transcription factor binding sites in the SALL2 ...identification of putative transcription factor binding sites in DNA ... See full document
16
Arq. NeuroPsiquiatr. vol.64 número1
... behavior of pituitary adenomas are not fully understood. In this study we investigated the presence of p53, Ki-67 and c-erb B2 in 38 pituitary adenomas with ... See full document
7
Expressão da proteína p53 em 106 adenomas pleomórficos de glândula salivar maior.
... the expression of oncogenes and other factors that influence malignant ...objective of this study was to analyze the histopathological features of malignant transformation in ... See full document
7
Reactivity of p53 protein in canine transmissible venereal tumor
... The expression of p53 protein was evaluated in canine transmissible venereal tumor (CTVT), as following: natural occurrence (n=8); resistant to chemotherapy (n=4); and allogeneic ... See full document
6
ZAC1 and SSTR2 are downregulated in non-functioning pituitary adenomas but not in somatotropinomas.
... ZAC1 expression levels were inversely associated with ...ZAC1 expression levels with the tumor invasiveness, but no association was ...levels of Ki-67 and p53 between invasive and non-invasive ... See full document
7
ISSN 0100-879X CLINICAL INVESTIGATION
... effector of PI3K is Akt kinase, which phospho- rylates target proteins regulating key processes such as cell proliferation and ...Akt expression associated with PIK3CA mutations in low-stage ... See full document
6
Expression of E-cadherin, Slug and NCAM and its relationship to tumor invasiveness in patients with acromegaly
... Pituitary adenomas account for 10–15% of primary intracranial ...(GH)-secreting adenomas account for 13% of all pituitary adenomas and cause ...objective of this ... See full document
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