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[PDF] Top 20 GPCRDB: information system for G protein-coupled receptors

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GPCRDB: information system for G protein-coupled receptors

GPCRDB: information system for G protein-coupled receptors

... 2010 GPCRDB release) from about 11 million sequences to about 80 ...species information is extracted and stored. The GPCRDB holds for each sequence one principal access ... See full document

11

Cell wall trapping of autocrine peptides for human G-protein-coupled receptors on the yeast cell surface.

Cell wall trapping of autocrine peptides for human G-protein-coupled receptors on the yeast cell surface.

... a Multi-beads shocker (Yasui Kikai, Osaka, Japan) with 0.5 mm glass beads. Cell lysates were centrifuged at 1,0006g for 5 min and the pellet was then washed three times with 10 mM Tris- HCl containing 1 mM PMSF. The ... See full document

10

Chemogenomic analysis of G-protein coupled receptors and their ligands deciphers locks and keys governing diverse aspects of signalling.

Chemogenomic analysis of G-protein coupled receptors and their ligands deciphers locks and keys governing diverse aspects of signalling.

... and information regarding their preferred G-protein subtype from the standardized IUPHAR [47] database (figure ...particular G-protein subtype, while most of them are able to undergo ... See full document

11

Casimiro, Andreia Palos

Casimiro, Andreia Palos

... repeat-containing G-protein-coupled receptors (LGRs) of the C1 ...relaxin receptors, described in ...these receptors remain unknown not only in Drosophila, but also in all ... See full document

105

The search for novel insecticide targets in the post-genomics era, with a specific focus on G-protein coupled receptors

The search for novel insecticide targets in the post-genomics era, with a specific focus on G-protein coupled receptors

... consequently led to increased sensitivity to the compound and delayed larval growth (Gordon & Wa- terhouse 2007). While this RNAi strategy has not been introduced into field practice as a form of biological con- ... See full document

7

Modulation of voltage-gated Ca2+ channels by G protein-coupled receptors in celiac-mesenteric ganglion neurons of septic rats.

Modulation of voltage-gated Ca2+ channels by G protein-coupled receptors in celiac-mesenteric ganglion neurons of septic rats.

... nervous system in mice increased dissemination of Gram-positive bacteria, while decreasing it with Gram- negative bacteria ...nervous system (SNS) plays a dual role in sepsis, which can be either beneficial ... See full document

16

Analysis of the goldfish Carassius auratus olfactory epithelium transcriptome reveals the presence of numerous non-olfactory GPCR and putative receptors for progestin pheromones

Analysis of the goldfish Carassius auratus olfactory epithelium transcriptome reveals the presence of numerous non-olfactory GPCR and putative receptors for progestin pheromones

... differentiation G-pro- tein coupled receptor 5 (Edg5) is a receptor for sphingo- sine 1-phosphate, which is responsible for neurite retraction and also keratinocyte growth arrest and differ- entiation ... See full document

17

A transplantable phosphorylation probe for direct assessment of G protein-coupled receptor activation.

A transplantable phosphorylation probe for direct assessment of G protein-coupled receptor activation.

... assessing G protein signaling are being used to determine whether a new compound is a full or partial ...direct information on receptor activation. However, structural information is only ... See full document

9

A robust and rapid method of producing soluble, stable, and functional G-protein coupled receptors.

A robust and rapid method of producing soluble, stable, and functional G-protein coupled receptors.

... Western blots and silver stains were used to detect the proteins and analyze their purity. Samples were prepared and loaded in Novex 10% Bis-Tris SDS-PAGE gels (Invitrogen) according to the manufacturer’s protocol, with ... See full document

6

Feeding and the rhodopsin family g-protein coupled receptors in nematodes and arthropods

Feeding and the rhodopsin family g-protein coupled receptors in nematodes and arthropods

... tachykinins) receptors tkr-1 and tkr-3 have been described (Keating et ...neurokinin-like receptors have been reported: the neurokinin receptor (NKD), the tachykinin receptor (DTKR; Li et ...invertebrate ... See full document

22

New perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathway

New perspectives in signaling mediated by receptors coupled to stimulatory G protein: the emerging significance of cAMP efflux and extracellular cAMP-adenosine pathway

... In addition to PDE, the intracellular concentration of cAMP is regulated by its efflux into the extracellular space through a specific transport system named multidrug resistance proteins (MRP; Cheepala et al., ... See full document

9

Histamine modulates dopaminergic neuronal survival by boosting microglial activity

Histamine modulates dopaminergic neuronal survival by boosting microglial activity

... Nervous System (CNS), histamine is also released by microglial cells and exerts its functions through the activation of four subtypes of G-protein coupled receptors: H1, H2, H3 and ... See full document

64

Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells.

Tre1, a G protein-coupled receptor, directs transepithelial migration of Drosophila germ cells.

... nos-GAL4 system for the analysis of even very early aspects of germ cell migration and ...GAL4 system, we have expressed many constitutively activated and dominant-negative forms of ...tested ... See full document

13

Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders.

Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders.

... regulate G protein-coupled receptors (GPCRs) in the central nervous system ...D2 receptors are enriched, is strongly innervated by the ventral tegmental area (VTA), which is the ... See full document

16

Expression and function of G-protein-coupled receptorsin the male reproductive tract

Expression and function of G-protein-coupled receptorsin the male reproductive tract

... relaxin receptors are often co-localized in tissues of the male reproductive system and may act in concert to regulate several aspects of ...acetylcholine receptors are found in Sertoli cells, where ... See full document

24

Rev. Bras. Reumatol.  vol.52 número1 en v52n1a09

Rev. Bras. Reumatol. vol.52 número1 en v52n1a09

... In view of those fi ndings, the same authors have evaluated sHLA-G and IL10 production and their relationship with the HLA-G 14-bp polymorphism in 156 patients with RA (treated with MTX or not). Peripheral ... See full document

10

PROTEIN STRUCTURE, RECEPTORS AND TRANSLOCATION ROUTES

PROTEIN STRUCTURE, RECEPTORS AND TRANSLOCATION ROUTES

... treatment of idiopathic chronic constipation as well as functional intestinal disorders and chronic inflammatory bowel disease (45,52,53). In addition, a promising field in biotechnology is the use of bacteriocin release ... See full document

11

Characterization of the levels and G-protein coupling of adenosine A2A receptors in hippocampus and striatum of transgenic rats overexpressing adenosine A2A receptors in the brain

Characterization of the levels and G-protein coupling of adenosine A2A receptors in hippocampus and striatum of transgenic rats overexpressing adenosine A2A receptors in the brain

... in transgenic rats overexpressing human adenosine A2A receptors in the brain. Neurobiol Learn Mem 2007;87:42-56. 15. Laurent C, Burnouf S, Ferry B, et al. A2A adenosine receptor deletion is protective in a mouse ... See full document

13

Metabolic parameters and emotionality are little affected in G-protein coupled receptor 12 (Gpr12) mutant mice.

Metabolic parameters and emotionality are little affected in G-protein coupled receptor 12 (Gpr12) mutant mice.

... Body weight was recorded in chow (R3, Lactamin, Stockholm, Sweden) fed mice weekly from 4–8 weeks of age and then at 16 and 20 weeks of age. Body composition at 8 weeks of age was assessed by dual energy X-ray ... See full document

8

Identification of novel glial genes by single-cell transcriptional profiling of Bergmann glial cells from mouse cerebellum.

Identification of novel glial genes by single-cell transcriptional profiling of Bergmann glial cells from mouse cerebellum.

... and receptors known or hypothesized to mediate cell-cell or cell-ECM ...and receptors such as brevican, tenascin C, integrin av, and dystroglycan-1, some of which are critical for structural integrity of ... See full document

15

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