[PDF] Top 20 Heparan sulfate proteoglycans: structure, protein interactions and cell signaling
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Heparan sulfate proteoglycans: structure, protein interactions and cell signaling
... extracellular cell matrix (ECM) components with cytoskeleton via transmembrane sur- face receptors, such as integrins and/or heparan sulfate proteoglycans ...activity and so ... See full document
21
Heparanase facilitates cell adhesion and spreading by clustering of cell surface heparan sulfate proteoglycans.
... the protein core ...of heparan sulfate, uronic acid (either glucuronic acid or iduronic acid) and N-acetyl glucosamine repeats compose the basic structure of the proteo- ...sulfation, ... See full document
10
Heparan sulfate and cell division
... Heparan sulfate was discovered 50 years ago by Jorpes and Gardell ...The heparan sulfate proteoglycans, that correspond to the glycosaminoglycan chains covalently linked to a ... See full document
6
Specific structural features of syndecans and heparan sulfate chains are needed for cell signaling
... syndecans, heparan sulfate proteoglycans, are abundant mol- ecules associated with the cell surface and extracellular matrix and consist of a protein core to which ... See full document
11
Probing the interaction between heparan sulfate proteoglycan with biologically relevant molecules in mimetic models for cell membranes: A Langmuir film study
... of proteoglycans associated to cell membranes is fundamental to comprehend bio- chemical process that occurs at the level of membrane ...a heparan sulfate proteoglycan obtained from ... See full document
7
Quantitative evaluation of experimental choroidal neovascularization by confocal scanning laser ophthalmoscopy: fluorescein angiogram parallels heparan sulfate proteoglycan expression
... metalloproteinases and the interaction of components of the extracellular matrix (ECM) with their receptors ...(17-19). Heparan sulfate proteoglycans (HSPG) have been shown to be involved in ... See full document
8
A targeted glycan-related gene screen reveals heparan sulfate proteoglycan sulfation regulates WNT and BMP trans-synaptic signaling.
... on heparan sulfate proteoglycans ...Dally-like protein (Dlp), and the trans- membrane Syndecan (Sdc) ...[76], and indeed appears to be selectively excluded from the perisynaptic ... See full document
21
Collagens and proteoglycans of the corneal extracellular matrix
... the structure and function of collagen ...peat proteoglycans (for a review, see Ref. 30). Proteoglycans are macromolecules com- posed of a protein core with covalently linked ... See full document
10
Modulators of axonal growth and guidance at the brain midline with special reference to glial heparan sulfate proteoglycans
... branching and terminal branching (Mendez- Otero et al. 1985, Bhide and Frost 1991, Jhaveri et ...tractive and repulsive molecules at the ...of cell motility and axonal sprouting have ... See full document
26
Heparan sulfate and control of cell division: adhesion and proliferation of mutant CHO-745 cells lacking xylosyl transferase
... -2 and -4 as well as glypican-1 possess HS which carry out this function ...of cell proliferation is due to its capacity to bind and act as co- receptor for growth factors, such as FGF ... See full document
5
Novel heparan sulfate-binding peptides for blocking herpesvirus entry.
... engineered and intended to facilitate an interaction with linear sulfated GAG molecules, notably heparin [39, ...target and image tissue amyloid deposits [25, 27], which contain hypersulfated HS and ... See full document
16
Acquisition of Anoikis Resistance Up-Regulates Syndecan-4 Expression in Endothelial Cells
... programmed cell death induced upon cell detachment from extracellular matrix, behaving as a critical mechanism in preventing adherent- independent cell growth and attachment to an ... See full document
23
NCAM1 Polysialylation
... prion protein sequence that replaces an aspartate with an asparagine residue at Position 178 on a background of the common methionine or methio- nine polymorphism at PrP C amino acid Position ...humans and ... See full document
25
Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.
... work, and other similar prior studies, ranked predicted associations and provided probabilities for interactions between baits and preys, building on the explicit nature of bait-prey ... See full document
10
Predicting Pharmacodynamic Drug-Drug Interactions through Signaling Propagation Interference on Protein-Protein Interaction Networks.
... chemical structure, target proteins, and side effects) [6, ...knowledge-based, and mechanism- based ...therapeutic, and genomic properties and constructed a data- base of adverse drug ... See full document
13
A non-hemorrhagic hybrid heparin/heparan sulfate with anticoagulant potential
... arinase and heparitinases I and II from Flavobacterium ...to heparan sulfates, in which around 50–60% of all disaccharides are U-ANAc/U- ANS (Andrade et ...N,6-O-sulfation and minor ... See full document
7
Rev. bras. ter. intensiva vol.24 número4 en a17v24n4
... assays and isobaric tags for relative and absolute quantiication (iTRAQ) were used to compare the protein expression from samples that were either treated or not treated with ...32 and 40 ... See full document
7
Heparan sulfate mediates trastuzumab effect in breast cancer cells
... [20,21]. Protein free GAG chains were prepared from the cellular fraction (cells plus ECM) and culture medium by incubation with maxatase (Biocon Industrial, Rio de Janeiro, RJ, Brazil; 4 mg/ml) overnight, ... See full document
13
Decorin is one of the proteoglycans expressed in Walker 256 rat mammary carcinoma
... Proteoglycan and glycosaminoglycan content was analyzed in a model of rat mammary carcinoma to study the roles of these compounds in ...acid and proteoglycans bearing chondroitin and/or ... See full document
11
Cell Signaling and Differential Protein Expression in Neuronal Differentiation of Bone Marrow Mesenchymal Stem Cells with Hypermethylated Salvador/Warts/Hippo (SWH) Pathway Genes.
... mouse and human mesenchymal stem cells to differentiate into ...day and then in a differentiation-inducing medium containing dimethylsulfoxide (DMSO) and butylated hydroxyanisole ...human and ... See full document
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