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[PDF] Top 20 Insights into the molecular basis of PRRXL1 function

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Insights into the molecular basis of PRRXL1 function

Insights into the molecular basis of PRRXL1 function

... one of a relatively small number of TFs that are expressed in both peripheral sensory neurons and their putative central targets in the spinal ...for Prrxl1 in establishing connectivity ... See full document

57

Insights into the function of the CRM1 cofactor RanBP3 from the structure of its Ran-binding domain.

Insights into the function of the CRM1 cofactor RanBP3 from the structure of its Ran-binding domain.

... shows the corresponding experiment for full-length RanBP3), in agreement with a previous semi-quantitative study ...pursued the structure of the RBD in its unbound form. We solved the ... See full document

10

Insights into the molecular mechanism of protein native-like aggregation upon methylglyoxal glycation

Insights into the molecular mechanism of protein native-like aggregation upon methylglyoxal glycation

... protein function, and is associated with several human neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease and Familial Amyloidotic ...stabilizes the formation of small ... See full document

42

Insights into the background of autonomic medicine

Insights into the background of autonomic medicine

... on the sinus node and other pacemaker cells, is involved in heartbeat regulation and atrial ...from the nucleus ambiguus and are activated by barore- ceptor ...activity, the absence of ... See full document

15

Molecular time-course and the metabolic basis of entry into dauer in Caenorhabditis elegans.

Molecular time-course and the metabolic basis of entry into dauer in Caenorhabditis elegans.

... by the use of GD and gnuplot. The current system is operated by an Apache-based web ...description of DauerDB construction, including GO clustering [48], is as follows: As data is deposited, ... See full document

10

Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging.

Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging.

... analysis of gene expression changes in the brains of Alzheimer’s patients confirms that AD is both similar and distinct from the process of normal ...a function of time to ... See full document

11

The spindle assembly checkpoint: new insights into its function, regulation and therapeutic implications

The spindle assembly checkpoint: new insights into its function, regulation and therapeutic implications

... by the motor activity of the cytoplasmic dynein [78, 109, 77, 81, 79], recruited to kinetochore by the RZZ complex via Spindly ...[110-115]. The high density of microtubules near ... See full document

209

Insights into regulatory mechanisms of the NIK-mediated antiviral defense: new components and the molecular bases of the defense

Insights into regulatory mechanisms of the NIK-mediated antiviral defense: new components and the molecular bases of the defense

... For the bipartite begomoviruses, the proteins required for replication (Rep and REn), transactivation of viral genes (TrAP), the suppression of RNAi defence functions (TrAP and AC4) and ... See full document

201

Molecular insights into the role of alfa-synuclein phosphorylation in synucleinopathies

Molecular insights into the role of alfa-synuclein phosphorylation in synucleinopathies

... that the final mature aggregates are the most dangerous for cell homeostasis (El-Agnaf et ...that the smaller, more soluble protein dimers and oligomers are the ones that exert toxicity ... See full document

126

Novel insights into the genomic basis of citrus canker based on the genome sequences of two strains of Xanthomonas fuscans subsp. aurantifolii

Novel insights into the genomic basis of citrus canker based on the genome sequences of two strains of Xanthomonas fuscans subsp. aurantifolii

... families of orthologous genes specific to them when compared to all other fully sequenced members of the genera Xanthomonas and Xylella (Additional file 2: Table ...half of these genes code ... See full document

25

Novel insights into the genomic basis of citrus canker based on the genome sequences of two strains of Xanthomonas fuscans subsp aurantifolii

Novel insights into the genomic basis of citrus canker based on the genome sequences of two strains of Xanthomonas fuscans subsp aurantifolii

... families of orthologous genes specific to them when compared to all other fully sequenced members of the genera Xanthomonas and Xylella (Additional file 2: Table ...half of these genes code ... See full document

25

The Structure of the T190M Mutant of Murine α-Dystroglycan at High Resolution: Insight into the Molecular Basis of a Primary Dystroglycanopathy.

The Structure of the T190M Mutant of Murine α-Dystroglycan at High Resolution: Insight into the Molecular Basis of a Primary Dystroglycanopathy.

... form of limb-girdle muscular dystrophy (LGMD2P) is an autosomal recessive disease caused by the point mutation T192M in α- ...that the mutation was responsible for a decrease in posttranslational ... See full document

21

Insights into the influence of the molecular structures of fluorinated ionic liquids on their thermophysical properties. A soft-SAFT based approach

Insights into the influence of the molecular structures of fluorinated ionic liquids on their thermophysical properties. A soft-SAFT based approach

... sites. The number of sites was chosen on the basis of the delocalization of the anion electric charge, due to the presence of the oxygen ... See full document

21

Setting Up the Perimeter of Tolerance: Insights into mTEC Physiology

Setting Up the Perimeter of Tolerance: Insights into mTEC Physiology

... and Function Laboratory, Instituto de Biologia Molecular e Celular, Porto, ...Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, ... See full document

5

Insights into the cellular function of YhdE, a nucleotide pyrophosphatase from Escherichia coli.

Insights into the cellular function of YhdE, a nucleotide pyrophosphatase from Escherichia coli.

... part of a large family of conserved pro- teins found in bacteria, archaea and ...in the regu- lation of cell division, their exact cellular function remains ...introduction of ... See full document

15

Insights into the N-Sulfation Mechanism: Molecular Dynamics Simulations of the N-Sulfotransferase Domain of Ndst1 and Mutants

Insights into the N-Sulfation Mechanism: Molecular Dynamics Simulations of the N-Sulfotransferase Domain of Ndst1 and Mutants

... using the 1.8 A ˚ resolution structure of 3- O-sulfotransferase bound to a heptasaccharide substrate using Autdock (PDBiD ...1T8T). The obtained reference RMSD was 0.49 for the lowest scoring ... See full document

12

Insights into the selectivity mechanisms of grapevine NIP aquaporins

Insights into the selectivity mechanisms of grapevine NIP aquaporins

... Likewise, the amino acid substitution in VvTnNIP6;1 at H2/H5 position (T118W and I239V) also resulted in declining the glycerol transport without affecting the water ...in the case of a ... See full document

14

New insights into the structural characteristics of irradiated crotamine

New insights into the structural characteristics of irradiated crotamine

... ure of hydrophobic residues makes crotamine unusually ...side of the molecule and the positively charged residues are clustered on the opposite ...on the surface of ... See full document

10

Insights from amphioxus into the evolution of vertebrate cartilage.

Insights from amphioxus into the evolution of vertebrate cartilage.

... orthologs of vertebrate cranial neural crest and cartilage ...expression of network component homologs in ...in the network as cranial neural crest (CNC) markers, cartilage markers, or effector genes ... See full document

9

New insights into the detection and molecular characterization of Cryptosporidium with emphasis in Brazilian studies: a review

New insights into the detection and molecular characterization of Cryptosporidium with emphasis in Brazilian studies: a review

... method of stool samples concentration for detection by optical microscopy aimed to increase the finding of parasites in these samples by examining density differences between different compounds ... See full document

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