[PDF] Top 20 Mitochondria, calcium and pro-apoptotic proteins as mediators in cell death signaling
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Mitochondria, calcium and pro-apoptotic proteins as mediators in cell death signaling
... homeostasis and signaling under physiological and cell death ...mM and cytosolic concentration is about 100 ...increases in cytosolic Ca 2+ stimulate mitochondrial uptake ... See full document
8
The mechanism mediating nuclear translocation of the apoptosis inducing factor (AIF)
... the death receptor to form the death-inducing signaling complex ...DISC, and the amount of procaspase-8 molecules in the DISC leads to their autocatalytic activation and ... See full document
83
Curcumin conjugated with PLGA potentiates sustainability, anti-proliferative activity and apoptosis in human colon carcinoma cells.
... induce apoptotic cell death in various types of cancer [25, 38, ...of apoptotic cell death induced by curcumin was mostly demon- strated by mitochondria-dependent ... See full document
24
Tip60 HAT activity mediates APP induced lethality and apoptotic cell death in the CNS of a Drosophila Alzheimer's disease model.
... pathways and their respective genes from online databases like Gene Ontology and the PANTHER classification ...such apoptotic pathways were misregulated in response to loss of Tip60’s HAT ... See full document
13
Application of flow cytometry to determine differential redistribution of cytochrome c and Smac/DIABLO from mitochondria during cell death signaling.
... c and Smac occurs differentially under various apoptotic inductions in different cell ...of proteins in the IMS to exit through the permeabilized ...Whilst in vitro ... See full document
10
Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases.
... during apoptotic cell death signaling, we next assessed whether this cleavage might also occur during CVB infection given that this virus often utilizes the direct cleavage of cellular innate ... See full document
16
Rev. Assoc. Med. Bras. vol.56 número6 en v56n6a24
... planned cell death is a biological phenomenon that is essential for the development and maintenance of a cell ...population. In this process, senescent or damaged cells are eliminated ... See full document
4
A mechanistic view of mitochondrial death decision pores
... transport and redox conditions that ultimately lead to major changes in the structure of mitochondrial proteins and ...inside and outside the mi- tochondria are important promoters of ... See full document
14
MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection.
... roles in death receptor-initiated extrinsic as well as mitochondria-initiated intrinsic apoptotic pathways, in response to stress stimuli, such as cytokines, DNA damages, heat shock ... See full document
15
Organopalladium compound 7b targets mitochondrial thiols and induces caspase-dependent apoptosis in human myeloid leukemia cells
... apoptosis. In order to investigate whether thiol oxidation and mitochondrial depolarization were involved in the cell death, it was investigated the release of cytochrome c from ... See full document
8
BH3 peptides induce mitochondrial fission and cell death independent of BAX/BAK.
... of cell death still remains unclear ...the mitochondria is important for the release of apoptogenic factors such as cytochrome c to induce cell death ...the mitochondria can ... See full document
16
Calcium and cell death signaling in neurodegeneration and aging
... family proteins. In addition, Bax and other Bcl-2 family members also possess a hydrophobic segment at their carboxyl terminal ends, which might be required for anchoring the protein to the ... See full document
9
β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells.
... involved in the b-lap- induced apoptotic cell death of breast cancer cells ...caspase-8 in death receptor-mediated cell death pathway [14], we observed that the ... See full document
12
Braz. J. Pharm. Sci. vol.53 número3
... glutaraldehyde in 0.1 M potassium phosphate bufer (P(K)). Cells were washed in P(K) bufer and post-ixed in 2% osmium tetroxide (Electron Microscopy Sciences, Fort Washington, PA, USA) ... See full document
10
Expanding the substantial interactome of NEMO using protein microarrays.
... seeded in 24-well plates and grown overnight in antibiotic-free DMEM containing 10% FCS to approximately 60% ...plasmid and 1600 ng of the different expression plasmids using Lipofectamine ... See full document
10
Increased anion channel activity is an unavoidable event in ozone-induced programmed cell death.
... L. cell line T87 [76] was ...a cell line (named T87) from the ecotype Columbia ...[32,37,42] and abiotic stress ...stimuli, in a similar manner to autonomous cellular responses in ... See full document
14
Fludarabine induces apoptosis in chronic lymphocytic leukemia - the role of P53, Bcl-2, Bax, Mcl-1, and Bag-1 proteins
... for cell survival after fludarabine treatment. Also, Bag-1 increased in patients with shorter LDT (P = ...observed in viable cells resistant to fludara- ...Bag-1 and Bcl-2 interactions enhance ... See full document
7
Rev. bras. farmacogn. vol.22 número2
... resulted in the isolation of wogonin, and ...HeLa cell lines and ...explored in this toxicity. The cells were cultured in RPMI medium and incubated with different ... See full document
9
Heparin modulates the expression of genes encoding pro and anti-apoptotic proteins in endothelial cells exposed to intestinal ischemia and reperfusion in rats
... HP and its derivatives have long been proposed for stroke ...mortality, and prevent early ...nadroparin and tinzaparin, has been tested in the treatment of acute IR lesions 13-18 ...IR ... See full document
5
A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production
... RENCA and NIH3T3 cells were treated with ...4 and 16 h. The cells were then washed twice with PBS and mechanically ...total proteins in the cell ex- tract, aliquots of 15–30 μg ... See full document
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