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[PDF] Top 20 The Nanos3-3'UTR is required for germ cell specific NANOS3 expression in mouse embryos.

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The Nanos3-3'UTR is required for germ cell specific NANOS3 expression in mouse embryos.

The Nanos3-3'UTR is required for germ cell specific NANOS3 expression in mouse embryos.

... previously in fishes and flies, in which miR430 and the Dnd1 protein, or the Smg, Glo and Osk proteins are involved in mRNA regulation via the ...nanos-39UTR. In mice, one ... See full document

10

Activation of GSK3β by Sirt2 is required for early lineage commitment of mouse embryonic stem cell.

Activation of GSK3β by Sirt2 is required for early lineage commitment of mouse embryonic stem cell.

... Sirt2 expression does not affect the self-renewal of mouse ESCs ...differentiation, the absence of Sirt2 inhibits the formation of ectoderm while promoting the differentiation of ... See full document

8

The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.

The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.

... In the present study, we generated Pik3c3 knockout mice and characterized the in vivo function of PIK3C3 during ...embryogenesis. The most prominent defect caused by Pik3c3 deletion ... See full document

10

Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition.

Geminin is required for zygotic gene expression at the Xenopus mid-blastula transition.

... Geminin expression we injected two-cell Xenopus embryos with 32 ng of anti-Geminin morpholino oligonucleotides (a-Gem MOs), which cause a ...reduction in the amount of Geminin protein ... See full document

13

In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells.

In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells.

... inducing germ cell differentiation from ES cells have been reported. In mice, germ cells have been generated from ES cells using monolayer culture [1], the formation of embryoid bodies ... See full document

10

Wdr74 is required for blastocyst formation in the mouse.

Wdr74 is required for blastocyst formation in the mouse.

... development in the mouse is a time of dynamic change in which the fertilized egg becomes a pluripotent embryo that subsequently develops into a blastocyst with two distinct ... See full document

9

Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse.

Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse.

... KMT1E, is a lysine methyltransferase (KMT) specific for the repressive histone H3 lysine 9 di- and tri-methyl (H3K9me2/me3) marks ...It is associated with transcriptional repression of ... See full document

26

Dicer is required for haploid male germ cell differentiation in mice.

Dicer is required for haploid male germ cell differentiation in mice.

... reported in male germ line that can function in post- transcriptional control of a wide variety of protein encoding mRNAs ...it is likely that at least some of the defects in ... See full document

12

14-3-3ε Is required for germ cell migration in Drosophila.

14-3-3ε Is required for germ cell migration in Drosophila.

... pole cell migration requires the protein products of several genes such as serpent (srp) and huckebein (hkb), engaged in normal mesoderm development [27,28,29] and others that affect pole cell ... See full document

11

Homozygous Inactivating Mutation in NANOS3 in Two Sisters with Primary Ovarian Insufficiency

Homozygous Inactivating Mutation in NANOS3 in Two Sisters with Primary Ovarian Insufficiency

... identiied in Drosophila, where it represses the translation of target mRNAs through binding to their 3UTR and has a conserved function in germ cell development across ... See full document

9

PhysioSpace: relating gene expression experiments from heterogeneous sources using shared physiological processes.

PhysioSpace: relating gene expression experiments from heterogeneous sources using shared physiological processes.

... Relating expression signatures from different sources such as cell lines, in vitro cultures from primary cells and biopsy material is an important task in drug development and ... See full document

17

Supplementation with the histone deacetylase inhibitor trichostatin A during in vitro culture of bovine embryos

Supplementation with the histone deacetylase inhibitor trichostatin A during in vitro culture of bovine embryos

... (TSA) is a histone deacetylase inhibitor that induces histone hyperacetylation and increases gene expression ...levels. The aim of the present study was to establish a suitable condition for ... See full document

5

Cell adhesion in zebrafish embryos is modulated by March 8.

Cell adhesion in zebrafish embryos is modulated by March 8.

... observed cell dissociation in response to excess March8 focused our attention on cadherins, major cell-cell adhesion proteins that have been well studied in Xenopus and zebrafish ... See full document

9

New evidence for balancing selection at the HLA-G locus in South Amerindians

New evidence for balancing selection at the HLA-G locus in South Amerindians

... at the HLA-G promoter region has previously been described (Tan et ...HLA-G expression and levels were already related to different situations (either in physiologi- cal or pathological conditions) ... See full document

5

Uncoupling different characteristics of the C. elegans E lineage from differentiation of intestinal markers.

Uncoupling different characteristics of the C. elegans E lineage from differentiation of intestinal markers.

... stage embryos (indicated above each blot compilation), separated briefly on an agarose gel side-by-side with like-staged samples of the same genotype, and blotted to membrane (’pseudo Northern’ blot; see ... See full document

14

Sex-specific signaling in the blood-brain barrier is required for male courtship in Drosophila.

Sex-specific signaling in the blood-brain barrier is required for male courtship in Drosophila.

... with the overall reduction in courtship (Table ...This is not due to locomotion defects, since males with feminized bbb perform indistinguishably from control flies in a short term activity ... See full document

11

Growth-arrest-specific protein 2 inhibits cell division in Xenopus embryos.

Growth-arrest-specific protein 2 inhibits cell division in Xenopus embryos.

... investigate the mechanism of Gas2-induced cell division arrest and cytokinesis failure, we used a wound-induced contractile array assay in Xenopus oocytes, which is also a model of cytokinesis ... See full document

12

Developmental origin and evolution of bacteriocytes in the aphid-Buchnera symbiosis.

Developmental origin and evolution of bacteriocytes in the aphid-Buchnera symbiosis.

... cases in which B. aphidicola have been lost during the evolution of ...not required for the developmental maintenance of bacteriocytes, it is possible that the bacter- iocyte ... See full document

7

Brahma is required for proper expression of the floral repressor FLC in Arabidopsis.

Brahma is required for proper expression of the floral repressor FLC in Arabidopsis.

... role in vegetative, embryonic and reproductive plant development ...[5,8,11,12]. Expression profiling using 10-day-old brm and wild-type (WT) seedlings showed that only 1% of the genes were ... See full document

11

Comparative 3'UTR analysis allows identification of regulatory clusters that drive Eph/ephrin expression in cancer cell lines.

Comparative 3'UTR analysis allows identification of regulatory clusters that drive Eph/ephrin expression in cancer cell lines.

... [19]. The respective coding regions and exon/intron boundaries are highly conserved among orthologues and paralogues, which is reflected by the redundant functions that Eph/ephrins can fulfill and by ... See full document

14

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