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[PDF] Top 20 A novel regulatory T cell population in the gut.

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A novel regulatory T cell population in the gut.

A novel regulatory T cell population in the gut.

... on the surface of T cells (the T cell receptor, or TCR), whose signaling prompts secretion of proteins called cyto- kines that coordinate the immune system’s efforts to fight off ... See full document

2

CD4+CD25hiCD127low regulatory T cells are increased in oral squamous cell carcinoma patients.

CD4+CD25hiCD127low regulatory T cells are increased in oral squamous cell carcinoma patients.

... occurs in about 400,000 individuals world-wide, and contribute to more than 222,000 deaths annually ...through the compilation of gene expression, chromosomal copy number and sequencing data for many types ... See full document

10

B-1 cell: the precursor of a novel mononuclear phagocyte with immuno-regulatory properties

B-1 cell: the precursor of a novel mononuclear phagocyte with immuno-regulatory properties

... happens in Xid mice as well as in animals whose peritoneal and pleural cavi- ties were previously irradiated, is sufficient to partially arrest B16 tumor growth and inhibit formation of meta- static ... See full document

8

Inflammation Enhances the Risks of Stroke and Death in Chronic Chagas Disease Patients

Inflammation Enhances the Risks of Stroke and Death in Chronic Chagas Disease Patients

... death in Chagas disease ...component in all ischemic processes, including the intravascular events triggered by vessel interruption, brain damage and ...repair. In this study, we evaluated ... See full document

18

Association among genetic predisposition, gut microbiota, and host immune response in the etiopathogenesis of inflammatory bowel disease

Association among genetic predisposition, gut microbiota, and host immune response in the etiopathogenesis of inflammatory bowel disease

... metabolites, the microbiome is essential for several aspects of host health, such as metabolism, immune response, and ...of the Firmicutes phylum, which, as described earlier, are reduced in IBD ... See full document

11

Anti-IL-2 Treatment Impairs the Expansion of T-reg Cell Population during Acute Malaria and Enhances the Th1 Cell Response at the Chronic Disease

Anti-IL-2 Treatment Impairs the Expansion of T-reg Cell Population during Acute Malaria and Enhances the Th1 Cell Response at the Chronic Disease

... of the Plasmodium ssp. are responsible for the pathology and morbidity caused by malaria, an infectious disease that remains a major devastating illness afflicting 350 to 500 million people annually and ... See full document

9

Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice.

Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice.

... of regulatory T-cells (Treg cells) in rats, but a first-in-man trial of the human CD28SA TGN1412 resulted in an unexpected cytokine release ...a novel mouse anti-mouse ... See full document

9

Towards the conservation of endangered avian species: a recombinant West Nile Virus vaccine results in increased humoral and cellular immune responses in Japanese Quail (Coturnix japonica).

Towards the conservation of endangered avian species: a recombinant West Nile Virus vaccine results in increased humoral and cellular immune responses in Japanese Quail (Coturnix japonica).

... arrived in North America in 1999 and is now ...as the Greater Sage-Grouse (Centrocercus uropbasianuts) and the Eastern Loggerhead Shrike (Lanius ludovicianus ...migrans). The virus has ... See full document

8

Oral tolerance to cancer can be abrogated by T regulatory cell inhibition.

Oral tolerance to cancer can be abrogated by T regulatory cell inhibition.

... stages the prognosis for patients suffering from oesophageal and gastric cancer remains consistently and significantly poorer than for patients with distal gastrointestinal tract cancers, despite advances ... See full document

11

Effect of dietary gluten on dendritic cells and innate immune subsets in BALB/c and NOD mice.

Effect of dietary gluten on dendritic cells and innate immune subsets in BALB/c and NOD mice.

... that cell populations of the adaptive immune system such as regulatory T cell subsets, T helper type 17 (Th17) and CD8 + cells are affected by gluten exposure in NOD mice ... See full document

13

1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients.

1,25-Dihydroxyvitamin D3 and its analog TX527 promote a stable regulatory T cell phenotype in T cells from type 1 diabetes patients.

... from the general population at KU Leuven (Leuven, ...on the basis of clinical criteria [23] and the presence of autoantibodies, were recruited from the clinical department of ... See full document

9

Unexpected Regulatory Role of CCR9 in Regulatory T Cell Development.

Unexpected Regulatory Role of CCR9 in Regulatory T Cell Development.

... regulate the pathogenesis of inflammatory bowel disease (IBD). As T cell trafficking to intestines is regulated through interactions between highly spe- cific chemokine-chemokine receptors, efforts ... See full document

16

T cell Maturation and Regulatory T Cell Differentiation: From the Thymus to the Periphery

T cell Maturation and Regulatory T Cell Differentiation: From the Thymus to the Periphery

... explains the impaired ability of peripheral mature T cells to acquire a Treg ...mature T cells, whether in the periphery or recirculating to the thymus, are refractory to IL-6 ... See full document

226

Physiological role of Kv1.3 channel in T lymphocyte cell investigated quantitatively by kinetic modeling.

Physiological role of Kv1.3 channel in T lymphocyte cell investigated quantitatively by kinetic modeling.

... predicting the kinetic behavior of ion channels and their function in ...on the individual activation, inactivation or recovery characteristics. The accuracy of the cell model is ... See full document

9

Regulatory T and B cells in asthmatic women

Regulatory T and B cells in asthmatic women

... linfocitos T reguladores no oscilaron de manera significativa desde el embarazo hasta después del ...linfocitos T reguladores también se vio alterada durante el embarazo tanto en las mujeres embarazadas ... See full document

25

The zwitterionic cell wall teichoic acid of Staphylococcus aureus provokes skin abscesses in mice by a novel CD4+ T-cell-dependent mechanism.

The zwitterionic cell wall teichoic acid of Staphylococcus aureus provokes skin abscesses in mice by a novel CD4+ T-cell-dependent mechanism.

... impaired in the mouse s.c. abscess model. The attenuated phenotype of the dltA mutant may be partially attributed to its susceptibility to killing by neutrophils and cationic microbial ... See full document

11

4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4+CD25+FoxP3+ T Regulatory Cell Suppression.

4-1BB Signaling in Conventional T Cells Drives IL-2 Production That Overcomes CD4+CD25+FoxP3+ T Regulatory Cell Suppression.

... role in immune regulation. The 4- 1BB signaling significantly contributes to T cell activation, acquisition of effector function, and long-term memory, more so for CD8 + than for CD4 + ... See full document

13

The Role of Regulatory T Cells and TH17 Cells in Multiple Myeloma

The Role of Regulatory T Cells and TH17 Cells in Multiple Myeloma

... (RQ-PCR) in bone marrow aspirates of 37 newly diagnosed MM patients, 4 newly diagnosed SPs, and 5 healthy controls (allogeneic transplant donors), Foxp3 was overexpressed in 72% of MM ...increase in ... See full document

5

Clonal expansions of CD8+ T cells with IL-10 secreting capacity occur during chronic Mycobacterium tuberculosis infection.

Clonal expansions of CD8+ T cells with IL-10 secreting capacity occur during chronic Mycobacterium tuberculosis infection.

... to the manufacturer’s instructions for intracel- lular cytokine staining (Cytofix/Cytoperm fixation/permeabiliza- tion solution kit with BD GolgiStop, BD Biosciences), following a 4 hr incubation with 1 m g/mL ... See full document

11

Regulatory T cell induction during Plasmodium chabaudi infection modifies the clinical course of experimental autoimmune encephalomyelitis.

Regulatory T cell induction during Plasmodium chabaudi infection modifies the clinical course of experimental autoimmune encephalomyelitis.

... underlying the heterogeneity of multiple sclerosis (MS) remain ...indicates the involvement of a complex genetic trait that probably requires an environmental factor, such as an infection, to be triggered ... See full document

7

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