[PDF] Top 20 The protective effect of regucalcin against radiation-induced testicular damage

... Although the exact role of each component of the epididymal fluid needs to be deciphered, acidification has been shown to be essential for the alterations on sperm surface proteins ... See full document

... regulation of radical production, elimination of radical precursors, metal chelation, or elevation of endogenous antioxidants ...body of evidence suggests that polyphenols regulate cell ... See full document

... investigated the protective effect against testicular injury of medi- cal ozone ...protected against I/R damage in an experi- mental unilateral TT model in ... See full document

... cells, the main metabolite of glycolysis, pyruvate, is not directed to the tricarboxylic acid cycle, and it is mainly converted into lactate by LDH in the cytosol ...[15]. The lactate ... See full document

... mimetic effect [7], second, by preserving SOD activity [33] and third by directly scavenging peroxynitrite ...catalyzes the decomposition of peroxynitrite to nitrate in vivo ...demonstrated ... See full document

... (UVB) radiation causes serious injury to skin cells and tissues (and especially to the epidermis) by inducing the production of inflammatory mediators and DNA lesions and, ultimately, by ... See full document

... preventing the toxic effects of box jellyfish venom in a cell-based assay [33] and animals ...On the other hand, treatment with topical application of lanolin cream and tetracycline cream were ... See full document

... by the liver via three main pathways; sulfonation, glucronidation and oxidation (Mitchell et ...1974). The first two pathways are quantitatively more important than the last one, but the ... See full document

... organelles against singlet oxygen-induced ...because of their long chain of conjugated double ...is the major plant source of vitamin A (23, ...one of the most ... See full document

... contribution of several systems (prostaglandins, nitric oxide, and afferent neurons) in gastric mucosal defense is well documented ...ablation of the sensory afferent neurons by capsaicin sig- ... See full document

... groups of Angiosperms. They belong to a class of natural compounds with great diversity of chemical structures and phar- macological ...genetic damage have been isolated from plants, and can ... See full document

... hepatic damage at very high doses and hence used as an efficient model to assess the efficacy of novel hepatoprotec- tive agents ...is the toxic metabolite of APAP, which induces lipid ... See full document

... history of infectious disease, no exposure to medicinal drugs, and no treatment with chemotherapy, radiation, or ...by the Ethics Committee of Núcleo de Medicina Tropical, Belem, Brazil ... See full document

... that the methanolic extract of ACM has potent radioprotective effect against genotoxicity induced by X-ray in human ...reduced the frequency of micronuclei in binucleated ... See full document

... protection against oxidative injury through its role in the cellular system of defense against R[LGDWLYHGDPDJH7KHGHFUHDVHLQWLVVXH*6+OHY- els after whole body irradiation may be due to ... See full document

... that testicular tissues and spermatozoa are very sensitive to reactive oxygen species attack and lipid ...peroxidation. The suscep- tibility of testicular tissues to oxidation is attribu- ted ... See full document

... hypofunction of the thyroid gland. Also, mean duration and amplitude of the T wave were higher and longer in chronic fluorosis as a result of a decrease in the level of ... See full document

... e effect against t est icu lar t ox icit y induced by t et racy cline dose of 20 m g/ 100 gBW for 14 day s in m ...ice. The ex t ract doses of 20, 50 and 100 m g/ 100 gBW used in ... See full document

... source of therapeutic agents. Due to the increasingly intensive use of medicinal plants, studies on their properties are needed for contributing to a safe and effective use (Akinboro & Bakare, ... See full document

... yet. The objective of this work was to investigate its antioxidant ability, then further discuss the antioxidant ...extract of Citri reticulatae pericarpium ...DNA damage assay, DPPH ... See full document