[PDF] Top 20 Role of the MAPK pathway in human lung epithelial-like A549 cells apoptosis induced by paraquat
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Role of the MAPK pathway in human lung epithelial-like A549 cells apoptosis induced by paraquat
... used in the world. Due to its high toxicity and lack of effective treatment measures, it has extremely high poisoning ...acute lung injury (ALI) or progres- sive pulmonary fibrosis. The ... See full document
6
Stanniocalcin-1 regulates extracellular ATP-induced calcium waves in human epithelial cancer cells by stimulating ATP release from bystander cells.
... enhances the calcium response downstream of extracellular nucleotides in epithelial cells, the same may not be true in other cell ...signaling in endothelial ... See full document
11
Specific uptake and genotoxicity induced by polystyrene nanobeads with distinct surface chemistry on human lung epithelial cells and macrophages.
... junctions, epithelial cells form a physical barrier in airways and alveoli against inhaled ...pulmonary cells [9,10]. Lunov et al. have recently shown that primary human macro- phages ... See full document
20
The Chromone Alkaloid, Rohitukine, Affords Anti-Cancer Activity via Modulating Apoptosis Pathways in A549 Cell Line and Yeast Mitogen Activated Protein Kinase (MAPK) Pathway.
... arrest by the activation of p21 leading to the activation of apoptosis ...to apoptosis. The majority of cancer therapy initiate apoptosis through ... See full document
18
Sorafenib inhibits epithelial-mesenchymal transition through an epigenetic-based mechanism in human lung epithelial cells.
... number of receptor tyrosine kinases [10,11,22]. However, in addition to the established functions in clinical trials, sorafenib likely has much broader effects than is currently ...known. ... See full document
9
Activation of p38/JNK pathway is responsible for embelin induced apoptosis in lung cancer cells: transitional role of reactive oxygen species.
... Increase in the fluorescence readings due to the release of AFC was monitored for every 5 min interval at lex 400 nm and lem 505 nm for 1h using EnSpire multimode plate reader (Perkin ... See full document
10
Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and in flammation damage
... one of the most notable active components of Panax ginseng, has been widely reported to exert anti- inflammatory ...(LPS)-induced apoptosis and inflammation in human renal ... See full document
9
Mechanisms of RON-mediated epithelial-mesenchymal transition in MDCK cells through the MAPK pathway
... determined the role and the mechanisms of RON in ...invasion of extracellular matrices (12). RON is involved in the EMT of MDCK ...transformation of ... See full document
9
Advanced glycation end products induce human corneal epithelial cells apoptosis through generation of reactive oxygen species and activation of JNK and p38 MAPK pathways.
... supports the idea that the overproduction of intracellular ROS caused by AGEs plays a important role in apoptosis ...AGEs induced fibroblasts apoptosis ... See full document
10
The role of alveolar epithelium in radiation-induced lung injury.
... source of type I collagen and fibrogenic/inflammatory cytokines in fibrotic ...be the most common one. Bone marrow-derived circulating cells have also been suggested as an alternative source ... See full document
9
MAPK Activation Is Essential for Waddlia chondrophila Induced CXCL8 Expression in Human Epithelial Cells.
... The MAPK signalling pathways have been shown to be important for CXCL8 release in cells infected with Chlamydia species ...at the genomic level [14], membrane structure [8] and ... See full document
11
The necrotic signal induced by mycophenolic acid overcomes apoptosis-resistance in tumor cells.
... (CML) cells express an oncogene protein consisting of the gene fusion of BCR (Breakpoint Cluster Region) and the tyrosine kinase ABL (Abelson), which behaves as a potent inhibitor ... See full document
9
Differential gene expressions of the MAPK signaling pathway in enterovirus 71-infected rhabdomyosarcoma cells
... RD cells were infected with EV71, the expression levels of c-Jun, c-Fos, IFN-, MEKK1 (MAP3K1), MLK3 (MAP3K11) and NIK (MAP3K14) revealed ...STAT1 in EV71-infected RD cells were ... See full document
8
Study of the role of RAF-1 in MAPK signaling in thyroid cancer cells
... to the other cell ...affect the apoptotic levels in TPC-1 but to a less extent in comparison with C643 and ...molecule in regulating apoptosis in cells harboring a ... See full document
129
The Roles of ROS and Caspases in TRAIL-Induced Apoptosis and Necroptosis in Human Pancreatic Cancer Cells.
... provided by tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) can induce death in cancer cells with little cytotoxicity to normal cells; this cell death has been ... See full document
15
Triclosan potentiates epithelial-to-mesenchymal transition in anoikis-resistant human lung cancer cells.
... Alteration of cancer cell toward mesenchymal phenotype has been shown to potentiate tumor aggressiveness by increasing cancer cell ...report the effect of triclosan, a widely used ... See full document
12
Retinal Pigmented Epithelial Cells Cytotoxicity and Apoptosis through Activation of the Mitochondrial Intrinsic Pathway: Role of Indocyanine Green, Brilliant Blue and Implications for Chromovitrectomy
... In the present paper, the safety profile of both dyes: AcV and MetB were evaluated; as the use of such dyes in chromovitrectomy was not reported before (source: Medline, ... See full document
11
Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase.
... important role in cancer cell apoptosis induced by anticancer drugs that cause DNA damage in the cell ...nucleus. The status of the cellular redox ... See full document
14
The role of PI3K/Akt signal pathway in the protective effects of propofol on intestinal and lung injury induced by intestinal ischemia/reperfusion
... injection of sodium pentobarbital (50 mg/ kg). The rats were placed in a supine position and kept the body temperature at 37 ± 1°C by application of a warming blanket ...set. ... See full document
13
Neoplastic transformation of breast epithelial cells induced by non-genotoxic stress
... resulting in activation of adenylyl cyclase and subsequent conversion of ATP into ...resulting in activation of transcription factors such as STAT3 and downstream kinases such as focal ... See full document
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