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[PDF] Top 20 Study of descending noradrenergic pain modulation in a model of neuropathic pain induced by chemotherapy

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Study of descending noradrenergic pain modulation in a model of neuropathic pain induced by chemotherapy

Study of descending noradrenergic pain modulation in a model of neuropathic pain induced by chemotherapy

... Enhanced pain sensitivity is a well-established hallmark of paclitaxel-induced neuropathy, but most of the animal studies on this subject have only focused on how and to what extent paclitaxel ... See full document

88

Delta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic pain.

Delta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic pain.

... effect of delta-opioid receptor (DOR) ligands in neuropathic pain is not diminished in contrast to other opioid receptor ligands, which lose their effectiveness as ...analgesics. ... See full document

14

GABA-Dependent Pain FAcilitation of Spinal 5-HT3R in Diabetic Neuropathic Pain

GABA-Dependent Pain FAcilitation of Spinal 5-HT3R in Diabetic Neuropathic Pain

... expression in glial cells (Guo et ...spinal pain modulation remain ...underlying pain facilitation induced by the pharmacological activation of spinal 5-HT3R in ... See full document

42

Intrathecal injection of spironolactone attenuates radicular pain by inhibition of spinal microglia activation in a rat model.

Intrathecal injection of spironolactone attenuates radicular pain by inhibition of spinal microglia activation in a rat model.

... existence of a functional interaction among microglia, proinflamma- tory cytokines and NMDA ...phosphorylation in the inflammatory pain models [4] and cancer pain models [10] while intrathecal ... See full document

10

Ameliorative potential of Ocimum sanctum in chronic constriction injury-induced neuropathic pain in rats

Ameliorative potential of Ocimum sanctum in chronic constriction injury-induced neuropathic pain in rats

... Furthermore, in this study chronic constriction injury was associated with the rise in the oxidative stress (rise in thio-barbituric acid reactive substances and superoxide anion content) and ... See full document

14

Dysregulation of the descending pain system in temporomandibular disorders revealed by low-frequency sensory transcutaneous electrical nerve stimulation: a pupillometric study.

Dysregulation of the descending pain system in temporomandibular disorders revealed by low-frequency sensory transcutaneous electrical nerve stimulation: a pupillometric study.

... index of the dispersion of the values, compared with the ...dispersion of TMD data was particularly seen during and after TENS, while the dispersion was reduced in the control ...aid in ... See full document

15

Unravelling the Role of Descending Pain Facilitation During Opioid-Induced Hyperalgesia. -Studies in a Model of Chronic Neuropathic Pain-

Unravelling the Role of Descending Pain Facilitation During Opioid-Induced Hyperalgesia. -Studies in a Model of Chronic Neuropathic Pain-

... explained by neuronal mechanisms, the emerging role of central immune signalling is revolutionizing opioid pharmacology ...role in initiating and maintaining increased nociception in response ... See full document

74

Development and validation of an animal model of prostate inflammation-induced chronic pelvic pain: evaluating from inflammation of the prostate to pain behavioral modifications.

Development and validation of an animal model of prostate inflammation-induced chronic pelvic pain: evaluating from inflammation of the prostate to pain behavioral modifications.

... findings of this study are that intraprostatic 3% l- carrageenan injection can induce inflammatory cell infiltration and COX2 expression increased in the rats ...enzyme of prostaglandin ... See full document

6

Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain.

Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain.

... mainly in medium- to large-diameter DRG neurons [5], but COX-1 was present around the perinuclear region of small-sized DRG ...neurons. In addition, our behavioral studies demonstrated that ... See full document

11

Pain determinants of pain in autosomal dominant polycystic kidney disease

Pain determinants of pain in autosomal dominant polycystic kidney disease

... In conclusion, the present analysis disclosed that renal volume (9-fold increased risk) and nephrolithia- sis (4-fold increased risk) were the most important determinant factors for pain in ADPKD ... See full document

2

Social distress and pain modulation : findings from healthy ans chronic pain patients

Social distress and pain modulation : findings from healthy ans chronic pain patients

... cries of a guinea pig could be relieved by administration of opioids, Eisenberger et ...physical pain and “social pain”. Social pain has been described as the suffering occurring ... See full document

211

Gene expression profile of sodium channel subunits in the anterior cingulate cortex during experimental paclitaxel-induced neuropathic pain in mice

Gene expression profile of sodium channel subunits in the anterior cingulate cortex during experimental paclitaxel-induced neuropathic pain in mice

... molecules in the ACC of a mouse model of PINP (Masocha, 2015a; Masocha, ...expression of sodium channels in the ACC during PINP has not been studied as ...expression of ... See full document

13

Evaluation of the mutagenic potential in a mouse model of peripheral neuropathic pain / Avaliação do potencial mutagênico em um modelo de dor neuropática periférica em camundongos

Evaluation of the mutagenic potential in a mouse model of peripheral neuropathic pain / Avaliação do potencial mutagênico em um modelo de dor neuropática periférica em camundongos

... assigned in three different groups (n=6 for each group): (I) Negative control group (NC), comprising naïve animals; (II) Positive control group (PC), whose animals were tested for verifying their reactivity to a ... See full document

11

Involvement of adenosine A1 receptor in electroacupuncture-mediated inhibition of astrocyte activation during neuropathic pain

Involvement of adenosine A1 receptor in electroacupuncture-mediated inhibition of astrocyte activation during neuropathic pain

... Neuropathic pain is a chronic pain condition caused by damage or dysfunction of the central or peripheral nervous ...on neuropathic pain, which is partially due to ... See full document

7

Prevalence of chronic pain in Brazil: a descriptive study

Prevalence of chronic pain in Brazil: a descriptive study

... written in any language, which reported data on the prevalence of chronic pain in the general Brazilian population or its specific classes, such as students, workers, the elderly ...concept ... See full document

4

Study of Genetic Factors Involved in Pain Perception and Morphine Analgesia in Cancer-Related Pain

Study of Genetic Factors Involved in Pain Perception and Morphine Analgesia in Cancer-Related Pain

... In Study II, the influence of selected SNPs was studied in the samples of 30 Caucasian cancer ...and pain sensitivity (COMT), and daily opioid doses were re- expressed as oral ... See full document

208

Historical development of epistemology and the study of pain: Place of neuromodulation of electroacupuncture in the experimental pain research

Historical development of epistemology and the study of pain: Place of neuromodulation of electroacupuncture in the experimental pain research

... diffusion of acupuncture and its related techniques in Cuba and the World, its mechanism of action is still controversial, being considered by the most sceptics as placebo or some kind ... See full document

28

Chemotherapy‑associated  induced by irinotecan : a novel animal model

Chemotherapy‑associated induced by irinotecan : a novel animal model

... increase in the survival rates of patients with metastatic CRC treated with the full therapeutic arma- mentarium, which often includes IRI as first-line ...policy of simply avoiding IRI, as suggested ... See full document

10

Detection of pain with neuropathic characteristics in patients with diabetes mellitus assisted in primary care units

Detection of pain with neuropathic characteristics in patients with diabetes mellitus assisted in primary care units

... prevalence of people with neu- ropathic pain was obtained through the application of the Dou- leur Neuropathique 4 questions questionnaire, which proved to be an effective and easily applied ...the ... See full document

6

Anti-hyperalgesic effect of electroacupuncture in a model of post-incisional pain in rats

Anti-hyperalgesic effect of electroacupuncture in a model of post-incisional pain in rats

... effective pain management with minimal collat- eral effects. In this study we have examined the effect of electroacu- puncture against the hyperalgesia developed in a model ... See full document

4

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