[PDF] Top 20 Survivin modulation in experimental pulmonary arterial hypertension
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Survivin modulation in experimental pulmonary arterial hypertension
... listed in the Acknowledgements section; however, the Program Director of the named group must be the one who signs for the group when the group's "author" signature is needed, ...publish in APS ... See full document
39
Cardioprotective effects of exercise precoditioning in an experimental model of left ventricular dysfunction secondary to pulmonary arterial hypertension
... Growing body of evidence supports the notion that exercise training is capable to provide a protective phenotype. Two lines of evidence strongly support this concept. First, a wide array of human epidemiological studies ... See full document
84
Evaluation of the effect of cholesterol supplementation on experimental pulmonary arterial hypertension
... increase in cardiomyocyte size, leading to HF ...develop hypertension following excessive salt ingestion ...develop hypertension and congestive HF, while DS rats fed only a low-diet salt are used as ... See full document
100
Insights on the epigenetic mechanisms underlying pulmonary arterial hypertension
... up-regulated in the lung of an experimental mouse model displaying PAH ...expression in an experimental mouse model of ...both in vivo and in vitro. MFN1 is involved in ... See full document
12
Pathophysiological Role and Therapeutic potential of Neuregulin-1 in Pulmonary Arterial Hypertension
... fact, in our study pulmonary arteries from MCT-injected animals presented endothelial dysfunction, as they were unable to relax in response to acetylcholine, presenting an increased ...negative ... See full document
73
Haemodynamic and neuroendocrine effects of tezosentan in chronic experimental pulmonary hypertension
... Pulmonary hypertension (PH), the most serious chronic disease of the pulmonary circulation, defined by mean pulmonary artery pressure greater than 25 mmHg, con- sists of an heterogeneous group ... See full document
25
Effect of thoracic epidural blockade on hypoxia-induced pulmonary arterial hypertension in rats
... Pulmonary arterial hypertension (PAH) is character- ized by profound increase in pulmonary vascular resistance in association with a degree of vascular proliferation and ... See full document
6
Glycogen synthase kinase 3beta contributes to proliferation of arterial smooth muscle cells in pulmonary hypertension.
... downregulated in MCT- PASMCs and in human iPAH patient lungs, along with other canonical Wnt signaling dependent genes we found that protein levels of GSK3ß increased in a time dependent fashion with ... See full document
13
Survivin and Smac/DIABLO: role of apoptosis in experimental PAH
... residues in the ligand-binding and/or kinase domain of BMPRII, which culminate in the traffic disruption of the mutant BMPRII to the cell surface retaining the receptor in the cytoplasm [28, ...hand, ... See full document
98
MEF2C-MYOCD and Leiomodin1 Suppression by miRNA-214 Promotes Smooth Muscle Cell Phenotype Switching in Pulmonary Arterial Hypertension.
... Further, in silico analyses using miRBase showed that miR-214 has two potential binding sites in the LMOD1 3’-UTR, and one in the MEF2C 3’-UTR, which are conserved among humans, chim- panzees, rhesus ... See full document
19
The role of urocortin-2 in pulmonary arterial hypertension
... The internal femoral vein was catheterized using a 24G catheter, under surgical microdissection (Wilde M651, Leica microsystems, Cambridge, UK) for infusion (Multi-Phaser, NE-100, New Era Pump Systems, NY, USA) of warm ... See full document
108
Survivin Role in Pulmonary Arterial Hypertension
... Manuel João Neves Ferreira Pinto Survivin Role in Pulmonary Arterial Hypertension.. março, 2012.[r] ... See full document
58
Preventive and therapeutic strategies for pulmonary arterial hypertension
... the experimental evidences of the therapeutic benefits of exercise training for the clinical management of PAH, most of the patients do not tolerate exercise at the time of diagnosis (Fowler, Gain et ...only ... See full document
247
Characterization and modulation of survivin in an experimental model of pulmonary arterial hypertension
... remodelling in the pulmonary arterial bed, thus providing a more significant decrease in pulmonary vascular resistance 151, 152, 172 ...PASMCs in PAH constitutes a striking ... See full document
63
Predictors of functional capacity in patients with pulmonary hypertension
... years, in addition to a better understanding of the pathophysiological mechanisms underlying PH, there has been significant development of methods and interventions with diagnostic and prognostic relevance ... See full document
6
Pulmonary Hypertension in Portugal: First Data from a Nationwide Registry
... 20 patients classified as PAH but without an available baseline RHC; therefore, they were not included in the analysis. This may have been due to the incomplete filling of the database fields and thus not ... See full document
9
Reversible Pulmonary Hypertension in an Infant Treated with Diazoxide
... and pulmonary pressure of 70 mmHg. In the next day, respiratory failure developed and so the patient was intubated and mechanically ...remained in normal ...Echocardiogram in one month later ... See full document
3
Pulmonary Hypertension in Portugal: First Data from a Nationwide Registry
... Introduction. Pulmonary arterial hypertension (PAH) is a rare disease that must be managed in specialized centers; therefore, the availability of epidemiological national data is ... See full document
9
In Silico studies of novel Sildenafil self-emulsifying drug delivery system absorption improvement for pulmonary arterial hypertension
... distribution in the resulting nanoemulsion (after dilution of SEDDS containing sildenafil in buffer solution) on a Horiba LB-550 DLS analyzer (Kyoto, Japan) with the following settings: detection angle of ... See full document
13
Effect of exercise training on right ventricular remodelling induced by pulmonary arterial hypertension
... are in continuity with the LV fibres, accounting for the systolic motion of the RV free wall toward the outflow ...increase in diastolic and systolic stretch on the RV wall is verified, which initially ... See full document
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