[PDF] Top 20 T follicular regulatory cells in human adaptive immunity and autoimmunity
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T follicular regulatory cells in human adaptive immunity and autoimmunity
... epithelial cells (SGEC) are central regulators of the autoimmune response by acting as atypical antigen-presenting cells and by constitutively expressing a plethora of immune-competent molecules, ... See full document
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Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy.
... Regulatory T cells (Treg) play a critical role in various immunological ...These cells dampen immune responses, which is important in maintenance of (self-) tolerance and ... See full document
13
Expression and function of TNF and IL-1 receptors on human regulatory T cells.
... IL-1R1 and TNFR2 on Tregs is less ...conventional T cells [33], and studies in mice have also shown that IL-1 enhances expansion of FOXP3+ cells [34], thus preferential ... See full document
12
Innate immunity and effector and regulatory mechanisms involved in allergic contact dermatitis
... Neutrophils in the activation and regulation of innate and adaptive ...Engeman T, Gorbachev AV, Kish DD, Fairchild ...CD8 T cells recruited into cutaneous antigen ... See full document
9
The Role of Regulatory T Cells and TH17 Cells in Multiple Myeloma
... anti-tumor immunity in MM. Tregs play an important role in the preservation of self-tolerance and modulation of overall immune responses against infections and tumor ...cells. ... See full document
5
INNATE, ADAPTIVE AND INTRINSIC IMMUNITY IN HUMAN IMMUNODEFICIENCY VIRUS INFECTION
... γδ T cells come into play remains poorly ...γδ T cells and the current dogma suggests these cells as first line of defence, ‘regulatory cells and a possible ... See full document
17
Modulation of regulatory T cells in autoimmune disease
... for human AID, at the present time it is not possible to predict whether healthy individuals with benign physiological auto-reactivity or sub-clinical autoimmunity in the form of physiological ... See full document
253
Murine and bovine γδ T cells enhance innate immunity against Brucella abortus infections.
... widespread and economically important agricul- tural and human disease in many regions of the ...brucellosis in cattle is Brucella abortus, a Gram-negative, facultative, intracellular ... See full document
12
Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells.
... diseases in mice, including type 1 diabetes [55], experimental allergic encephalomyelitis [36] and colitis ...of adaptive or inducible (iTregs), especially in the gut environment [14], ... See full document
11
TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity.
... Regulatory T cells (Tregs) maintain immune homeostasis by limiting inflammatory ...role in the regulation of innate and adaptive immunity by mediating signals from various ... See full document
12
Impact of dietary gluten on regulatory T cells and Th17 cells in BALB/c mice.
... studies in non-obese diabetic (NOD) mice as well as Biobreeding (BB) rats have documented that the pathogenesis of type 1 diabetes (T1D) is influenced by diet ...onset in NOD mice: the diabetes incidence ... See full document
12
The repertoire and specificity of follicular regulatory T cells
... divided in two main groups: cytotoxic ILCs and non-cytotoxic ...(NK) cells, while the second is composed by group 1, 2, and 3 of ILCs ...these cells have common characteristics with the ... See full document
196
Follicular helper T cell in immunity and autoimmunity
... Tfh cells are a central source of IL-21 in germinal centers of secondary lymphoid organs, provid- ing cognate help to B cells in the germinal center dynamic microenvironment, acting specially ... See full document
11
Focusing on the epigenetic control of regulatory T cells
... células T reguladoras (Treg), essenciais à resposta a estímulos autoimunes, à manutenção da tolerância imunitária e homeostase, sendo amplamente utilizado como um marcador específico das células ... See full document
38
Dysregulation of T lymphocyte proliferative responses in autoimmunity.
... deficit in any APC ...B cells using the MACS magnetic separation technique. B cells were selectively depleted with the use of anti-B220 ...antibody and was . 95% efficient in all ... See full document
8
Innate and adaptive immunity gene expression of human keratinocytes cultured of severe burn injury
... chain and a beta ...tissues and how this defect contributes to the increased susceptibility to Pseudomonas aeruginosa burn-wound ...by cells that express ITGAM that has abilities to suppress ... See full document
8
Progranulin facilitates conversion and function of regulatory T cells under inflammatory conditions.
... numbers and percentage of CD4+CD25+Foxp3+ T cells in thymus, spleen, and lymph nodes in different ages of mice ...1). In addition, mice in PGRN- treated group have ... See full document
11
THE ROLE OF ANTIGEN PRESENTING CELLS IN IMMUNE REGULATION MEDIATED BY REGULATORY T CELLS
... described in figure ...peptide and labeled with 0.25mM CFSE (CFSE hi ), and the other half was loaded with HA peptide and labeled with ...OVA-loaded and HA-loaded DC were then mixed at ... See full document
138
The origin of tumour-infiltrating regulatory T cells
... Normal cells (in grey) are transformed into tumour cells (in red) by the action of some carcinogens, promoting their proliferation/survival (top ...markers and their growth generate a ... See full document
82
Genetics and regulatory impact of alternative polyadenylation in human B-lymphoblastoid cells.
... variation in 3 9-end usage impacted gene expression, using as case studies IRF5 and DIP2B, which lie in genomic regions associated with susceptibility to lupus [15] and colorectal cancer [55], ... See full document
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