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[PDF] Top 20 The long path from QTL to gene.

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The long path from QTL to gene.

The long path from QTL to gene.

... in the 1990s of high density genetic maps of the mouse and rat based on simple sequence length polymor- phisms led to an explosion of activity directed toward the identification of quan- ... See full document

3

Alumni from the Polytechnic of Leiria: path & challenges

Alumni from the Polytechnic of Leiria: path & challenges

... of the Polytechnic of Leiria was formally constituted in February 2012 with the aim of recovering alumni relations, facilitating interactions, promoting the sharing of experiences and reinforcing ... See full document

9

Patrícia P Souza, Débora N Santos, Sérgio D J Pena, Glória R Franco+

Patrícia P Souza, Débora N Santos, Sérgio D J Pena, Glória R Franco+

... of the tryptophan/aspartate (WD) repeat family, which binds to the retinoblastoma (Rb) ...corresponds to the smallest subunit of the chromatin assembly factor and is able ... See full document

8

Long-term response to sulfonylurea in a patient with diabetes due to mutation in the KCNJ11 gene

Long-term response to sulfonylurea in a patient with diabetes due to mutation in the KCNJ11 gene

... due to p.G53D mutation in KCNJ11. Following the transfer from insulin to SU we observed marked improvement in glycemic control that was maintained over the follow-up period, despite ... See full document

3

Dreaming With BRICs: The Path to 2050

Dreaming With BRICs: The Path to 2050

... potential to post higher growth rates as they catch up with the developed ...comes from two sources. The first is that developing economies have less capital (per worker) than developed ... See full document

24

Large-scale in silico mapping of complex quantitative traits in inbred mice.

Large-scale in silico mapping of complex quantitative traits in inbred mice.

... used to verify causal variants from highly-refined QTL regions immediately after GWA scans ...resources from murine gene-deficiency and/or transgenic models, we have identified 10 ... See full document

14

Gremlin enhances the determined path to cardiomyogenesis.

Gremlin enhances the determined path to cardiomyogenesis.

... exposure to DMSO alone (a), Grem1 (125 ng/ml) and DMSO (b) for 14 days. The medium, including Grem1 and DMSO, was changed every ...exhibited the strongest contraction. (C) RT-PCR analysis of ... See full document

10

Identification of Dw1, a Regulator of Sorghum Stem Internode Length.

Identification of Dw1, a Regulator of Sorghum Stem Internode Length.

... corresponding to allelic variation at the Dw1 locus in a panel of grain genotypes many of which included BTx406 in their ...linked to Sb_HT9.1 identified a region of SBI-09 from 57.14–57.21, ... See full document

16

Long-range regulatory polymorphisms affecting a GABA receptor constitute a quantitative trait locus (QTL) for social behavior in Caenorhabditis elegans.

Long-range regulatory polymorphisms affecting a GABA receptor constitute a quantitative trait locus (QTL) for social behavior in Caenorhabditis elegans.

... second gene close to the II-QTL is exp-1, which encodes a c- aminobutyric acid (GABA)-gated cation channel [40]; the stop codon of exp-1 is ...away from the 6.2 kb ... See full document

13

A path to discovery: the career of Maclyn McCarty.

A path to discovery: the career of Maclyn McCarty.

... of the acceptance of the concept that “genes are DNA” deserve the scholarly praise they have received ...[5,6]. The claim was, indeed, subject to a formidable, but predictable, round of ... See full document

3

DE BOWERS A WINDSOR: O LONGO TRAJETO CONSTITUCIONAL DA LIBERDADE AO ENCONTRO COM A IGUALDADE E A DIFERENÇA -- FROM BOWERS TO WINDSOR: THE LONG CONSTITUTIONAL PATH OF FREEDOM TO FIND THE EQUALITY AND DIFFERENCE

DE BOWERS A WINDSOR: O LONGO TRAJETO CONSTITUCIONAL DA LIBERDADE AO ENCONTRO COM A IGUALDADE E A DIFERENÇA -- FROM BOWERS TO WINDSOR: THE LONG CONSTITUTIONAL PATH OF FREEDOM TO FIND THE EQUALITY AND DIFFERENCE

... and the love we commit to one another must be equal as ...have long fought for equal treatment under the law; for children whose parents’ marriages will now be recognized, rightly, as ... See full document

32

Variance heterogeneity in Saccharomyces cerevisiae expression data: trans-regulation and epistasis.

Variance heterogeneity in Saccharomyces cerevisiae expression data: trans-regulation and epistasis.

... in the vQTL region on Chromosome 13, (Table S4), the most interesting being TAF8 (YML114C) that, like URA3 and URA4, also effects pyrimidine metabolism through the transcription factor ...in ... See full document

11

Detection and Validation of QTL Affecting Bacterial Cold Water Disease Resistance in Rainbow Trout Using Restriction-Site Associated DNA Sequencing.

Detection and Validation of QTL Affecting Bacterial Cold Water Disease Resistance in Rainbow Trout Using Restriction-Site Associated DNA Sequencing.

... From the 418 predicted ORFs, we applied further filtering to identify potential candidate ...and gene expression experiments on the response to Fp injection in genetically ... See full document

14

Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network.

Identification of colorectal cancer related genes with mRMR and shortest path in protein-protein interaction network.

... of the most important and challenging problems in biomedicine and genomics is how to identify the disease ...method to identify colorectal cancer-related genes based on (i) the ... See full document

12

Leptin and hypothalamic gene expression in early- and late-maturing Bos indicus Nellore heifers

Leptin and hypothalamic gene expression in early- and late-maturing Bos indicus Nellore heifers

... related to leptin ...kg to 300 kg each were selected from a population of 100 Nellore ...used to quantify the expression of the leptin gene (LEP) in adipose tissues and ... See full document

8

National Highway Alignment from Namakkal to Erode Using  GIS

National Highway Alignment from Namakkal to Erode Using GIS

... was to develop a tool to locate a suitable less route between two ...points. The GIS approach using ground parameters and spatial analysis provided to achieve this ...resulting from ... See full document

11

Using a high finesse optical resonator to provide a long light path for differential optical absorption spectroscopy: CE-DOAS

Using a high finesse optical resonator to provide a long light path for differential optical absorption spectroscopy: CE-DOAS

... that the LED radiating area actually imaged into the resonator is of the order of 200×200 ...essential to use a high total power LED, which gains its power not from high surface ... See full document

31

A course design workshop as a possible path from a content-centered to a learning-centered teaching

A course design workshop as a possible path from a content-centered to a learning-centered teaching

... order to conduct these lines of action, the university created, in 2015, its center for teaching and learning whose main task is to support pro- fessors in the process of innovation of their ... See full document

20

The evolution of gene expression QTL in Saccharomyces cerevisiae.

The evolution of gene expression QTL in Saccharomyces cerevisiae.

... regulatory QTL In contrast to our estimates of a 16%–24% deficiency in the number of cis-acting QTL, approximately 94% of genes show heritable expression variation between BY and RM (see Text ... See full document

11

EFFECTS OF WIRE LAG IN WIRE ELECTRICAL DISCHARGE MACHINING (WEDM)

EFFECTS OF WIRE LAG IN WIRE ELECTRICAL DISCHARGE MACHINING (WEDM)

... But to date, very little is known about how wire-lag depends on various combinations of control parameters in ...model to calculate wire-lag for a given cutting speed. The user must continuously ... See full document

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