Top PDF Transgenic mice for a tamoxifen-induced, conditional expression of the Cre recombinase in osteoclasts.
Transgenic mice for a tamoxifen-induced, conditional expression of the Cre recombinase in osteoclasts.
... investigated the specificity of recombination in ...with tamoxifen for 3 days at day ...staining in long bones. Staining could also be seen in vertebrae, calvaria and craniums ...
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Split-cre complementation indicates coincident activity of different genes in vivo.
... that Cre-dependent recombination driven by GFAP or PLP promoters during embryonic development labels distinct glial and neuronal cell populations ...active in separate lineages or whether coincident ...
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A non-specific effect associated with conditional transgene expression based on Cre-loxP strategy in mice.
... since the Cre-loxP technology was first applied to conditionally express transgenes in mice in 1992 ...[1,2]. In recent years, the use of loxP-containing transgenes ...
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GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.
... member of the polycomb repressive complex 1 and plays different roles during embryonic development, depending on the developmental ...over expression is observed in many types of ...
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Conditional expression of Wnt4 during chondrogenesis leads to dwarfism in mice.
... mutants. In addition, in growth plates of R26 floxneoWnt4 ; Col2a1-Cre mutants, the zone of Col2a1 hybridization was significantly smaller yet the Ihh zone essentially ...
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Conditional transgenic expression of PIM1 kinase in prostate induces inflammation-dependent neoplasia.
... solely induced by Pim1 overexpression and also the effect of Pim overexpression in the physiological settings of hormone- induced mPIN and loss of one Pten ...
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Activation of Cre recombinase alone can induce complete tumor regression.
... The Cre/loxP system is a powerful tool for generating conditional genomic recombination and is often used to examine the mechanistic role of specific genes in ...However, ...
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Hemizygous Le-Cre transgenic mice have severe eye abnormalities on some genetic backgrounds in the absence of LoxP sites.
... type of Cre toxicity involves the action of Cre recombinase on cryptic pseudo-loxP sites, which are present in the endogenous mouse genome [54,55] but, to have any ...
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Immature B Cell Egress from Bone Marrow Is SOCS3 Independent.
... function in vitro [27, 29–31]. In turn, shortly after engaging CXCL12, CXCR4 signaling through JAK2 and JAK3, and several STATs, also promoted SOCS3 expression in IM-9 cell line [27, ...
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Genome engineering via homologous recombination in mouse embryonic stem (ES) cells: an amazingly versatile tool for the study of mammalian biology
... strategies in which the expression of a mutation would be rendered con- ditional (for a review, see Gu et ...on the remarkable properties of the Cre/loxP ...system. ...
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A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice.
... gene expression post-transcriptionally. MiRNAs are implicated in various biological processes associated with obesity, including adipocyte differentiation and lipid ...inhibition of miRNA maturation ...
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Avaliação neuroquímica do sistema colinérgico de camundongos com o gene do transportador vesicular de acetilcolina (VAChT) modificado geneticamente
... decrease in the frequency of MEPPs was also ...decrease in MEPP frequency is not the result of alterations in the readily releasable pool of ...that ...
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Foxn1 Transcription Factor Regulates Wound Healing of Skin through Promoting Epithelial-Mesenchymal Transition.
... gene expression in response to injury. We focused on the role of a transcription factor, Foxn1, whose expression is limited to the skin and thymus ...inactivity in nude ...
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Calpain 4 is not necessary for LFA-1-mediated function in CD4+ T cells.
... family of cysteine proteases have been found to have an important role in a diverse number of cellular events ranging from regulation of the actin cytoskeleton (reviewed in [6]) ...
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Rank/Rankl/opg: literature review
... expressed in the inflamed synovium; the presence of osteoclasts precursors in the inflamed synovial tissue and that the factors needed to local osteoclastogenesis ...
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WP114 No Impact of Rural Development Policies? No Synergies with Conditional Cash Transfers? An Investigation of the IFAD-Supported Gavião Project in Brazil
... than in isolation. We estimate the impacts —and possible synergies—of a rural development project (Pro-Gavião) and the Brazilian conditional cash transfer program (Bolsa ...Família). ...
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Synthesis Of Arts In Architecture Of Uzbekistan Of The Ancient Period
... accommodation of bas-relief panels [34]. So, there were no regularities to install the sculptures and "the whole sculpture was seen as one of the kinds of inner decor ...
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A Role for MicroRNA-155 Expression in Microenvironment Associated to HPV-Induced Carcinogenesis in K14-HPV16 Transgenic Mice
... number of diseases most notably cervical cancer. K14- HPV16 transgenic mice expressing the HPV16 early genes in squamous epithelial cells provide a suitable experimental model for ...
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RANK, RANKL and OPG signaling pathway
... to the TNFR superfamily, is synthe- sized as a type I homotrimeric transmembrane protein, and is expressed by different tissues such as skeletal muscle, thymus, liver, colon, mamma- ry glands, prostate, pancreas, ...
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Bihao Caoa , Zhiyin Huanga , Guoju Chena and Jianjun Lei
... on the genetic engineering of nuclear male sterility and its restoration had been reported and had emerged as tangible options for development of male sterile/restorer lines (Mariani et ...NMS-plants ...
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