... investigated the specificity of recombination in ...with tamoxifen for 3 days at day ...staining in long bones. Staining could also be seen in vertebrae, calvaria and craniums ...
... that Cre-dependent recombination driven by GFAP or PLP promoters during embryonic development labels distinct glial and neuronal cell populations ...active in separate lineages or whether coincident ...
... since theCre-loxP technology was first applied to conditionally express transgenes inmicein 1992 ...[1,2]. In recent years, the use of loxP-containing transgenes ...
... member ofthe polycomb repressive complex 1 and plays different roles during embryonic development, depending on the developmental ...over expression is observed in many types of ...
... mutants. In addition, in growth plates of R26 floxneoWnt4 ; Col2a1-Cre mutants, the zone of Col2a1 hybridization was significantly smaller yet the Ihh zone essentially ...
... solely induced by Pim1 overexpression and also the effect of Pim overexpression inthe physiological settings of hormone- induced mPIN and loss of one Pten ...
... TheCre/loxP system is a powerful tool for generating conditional genomic recombination and is often used to examine the mechanistic role of specific genes in ...However, ...
... type ofCre toxicity involves the action ofCrerecombinase on cryptic pseudo-loxP sites, which are present inthe endogenous mouse genome [54,55] but, to have any ...
... function in vitro [27, 29–31]. In turn, shortly after engaging CXCL12, CXCR4 signaling through JAK2 and JAK3, and several STATs, also promoted SOCS3 expressionin IM-9 cell line [27, ...
... strategies in which theexpressionof a mutation would be rendered con- ditional (for a review, see Gu et ...on the remarkable properties oftheCre/loxP ...system. ...
... gene expression post-transcriptionally. MiRNAs are implicated in various biological processes associated with obesity, including adipocyte differentiation and lipid ...inhibition of miRNA maturation ...
... decrease inthe frequency of MEPPs was also ...decrease in MEPP frequency is not the result of alterations inthe readily releasable pool of ...that ...
... gene expressionin response to injury. We focused on the role of a transcription factor, Foxn1, whose expression is limited to the skin and thymus ...inactivity in nude ...
... family of cysteine proteases have been found to have an important role in a diverse number of cellular events ranging from regulation ofthe actin cytoskeleton (reviewed in [6]) ...
... expressed inthe inflamed synovium; the presence ofosteoclasts precursors inthe inflamed synovial tissue and that the factors needed to local osteoclastogenesis ...
... than in isolation. We estimate the impacts —and possible synergies—of a rural development project (Pro-Gavião) and the Brazilian conditional cash transfer program (Bolsa ...Família). ...
... accommodation of bas-relief panels [34]. So, there were no regularities to install the sculptures and "the whole sculpture was seen as one ofthe kinds of inner decor ...
... number of diseases most notably cervical cancer. K14- HPV16 transgenicmice expressing the HPV16 early genes in squamous epithelial cells provide a suitable experimental model for ...
... to the TNFR superfamily, is synthe- sized as a type I homotrimeric transmembrane protein, and is expressed by different tissues such as skeletal muscle, thymus, liver, colon, mamma- ry glands, prostate, pancreas, ...
... on the genetic engineering of nuclear male sterility and its restoration had been reported and had emerged as tangible options for development of male sterile/restorer lines (Mariani et ...NMS-plants ...