[PDF] Top 20 Undecylprodigiosin induced apoptosis in P388 cancer cells is associated with its binding to ribosome.
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Undecylprodigiosin induced apoptosis in P388 cancer cells is associated with its binding to ribosome.
... of cancer cell growth has been known to be primarily mediated by apoptosis and cell cycle ...cytometry to analyze cell cycle phase distribution and apoptosis upon UP ...treatment. ... See full document
10
Yiwen Li, Yuqing Xu, Bo Lei, Wenxiu Wang, Xin Ge and Jingrui Li
... accumulates in the cytoplasm where it binds to the protein Apaf-1. Binding of pro-caspase-9 to Apaf-1 oligomers results in the formation of an apopto- some, eventually leading to ... See full document
9
Activation of p38/JNK pathway is responsible for embelin induced apoptosis in lung cancer cells: transitional role of reactive oxygen species.
... demonstrated to possess a wide range of therapeutic properties, however, the mechanisms by which it exerts anticancer effects are not yet ...changes associated during early apoptotic phase, we have ... See full document
10
BEX1 promotes imatinib-induced apoptosis by binding to and antagonizing BCL-2.
... BEX1 is over-expressed in a subset of primary breast cancers [26] and has been shown to prevent breast cancer cells from undergoing apoptosis ...induces apoptosis and ... See full document
8
The Roles of ROS and Caspases in TRAIL-Induced Apoptosis and Necroptosis in Human Pancreatic Cancer Cells.
... Normal cells are reported to show TRAIL-resistance with their preferential expression of DcRs ...and its DR are expected to be useful anti-cancer molecules and targets and have ... See full document
15
Adiponectin is protective against endoplasmic reticulum stress-induced apoptosis of endothelial cells in sepsis
... increase in total and HMW adiponectin, which is related to clinical recovery from sepsis (20) (Supplementary Table ...and is involved in the mechanisms of ...was to investigate ... See full document
10
Induction of cancer cell death by apoptosis and slow release of 5fluoracil from metalorganic frameworks CuBTC
... aimed to evaluate the mechanism associated with cytotoxic activity displayed by the drug 5- fluorouracil incorporated in Cu-BTC MOF and its slow delivery from the Cu-BTC ...performed ... See full document
7
Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells.
... according to the manufacturer’s ...used to amplify gene transcripts. The reaction was amplified in a thermal cycler (Eppendrof, ...(mentioned in S1 Table) for 30 sec; elongation at 72°C for ... See full document
21
PI3K inhibition enhances doxorubicin-induced apoptosis in sarcoma cells.
... sarcoma cells to doxorubicin ...DOX in several sarcoma cell lines and interacts with DOX in the induction of ...resulted in DOX accumulation. However, the enhancement of ... See full document
12
Bcl-xL silencing induces alterations in hsa-miR-608 expression and subsequent cell death in A549 and SK-LU1 human lung adenocarcinoma cells.
... available in Figure ...4.4260.08 in A549 cells with a knockdown of 75.1968.32% in bcl-xL expression when compared with non-transfected (NTC) A549 ...SK-LU1 cells ... See full document
14
Inhibition of methyltransferases accelerates degradation of cFLIP and sensitizes B-cell lymphoma cells to TRAIL-induced apoptosis.
... It is believed that cancer cells are particularly sensitive to cell death induced by tumor necrosis factor α–related apo- ptosis-inducing ligand ...many cancer cells show ... See full document
17
Myeloid-derived suppressor cells and associated events in urethane-induced lung cancer
... added to the lungs, and the organ was ...removed with centrifugation at 11,000 rpm at 4 ˚ C for 30 ...used to measure the protein concentration (Bradford - ELISA ...gel to a nitrocellulose ... See full document
7
A low-testosterone state associated with endometrioma leads to the apoptosis of granulosa cells.
... the apoptosis via the Akt-FoxO3a pathway in the COV434 granulosa ...COV434 cells were incubated in phenol red-free DMEM supplemented with 2% Charcoal Stripped Fetal Bovine Serum ... See full document
17
Rev. bras. farmacogn. vol.25 número3
... product in Asian countries. Fucoidan is a major sulfated polysaccharide found in brown seaweed; it has been well characterized and is known to have various biological functions, ... See full document
6
A novel compound NSC745885 exerts an anti-tumor effect on tongue cancer SAS cells in vitro and in vivo.
... antibiotics is a major concern in their clinical application ...compound in cardiomyocyte has not been evaluated in previous studies ...[18]. In this study, we evaluated the toxicity of ... See full document
13
Acidic environment leads to ROS-induced MAPK signaling in cancer cells.
... order to assess different mechanisms of cell death the protein content per dish (overall cell viability), induction of apoptosis (caspase-3 activity) and necrosis (LDH-release) were ...change in cell ... See full document
12
Stabilization of Nrf2 protein by D3T provides protection against ethanol-induced apoptosis in PC12 cells.
... PC12 cells were washed in phosphate-buffered saline (PBS) and lysed for 30 min in RIPA lysis buffer (PBS, ...Dithiothreitol) with 1 mM PMSF and protease cocktail inhibitors (Roche, Applied ... See full document
5
Mitotic arrest and apoptosis in breast cancer cells induced by Origanum majorana extract: upregulation of TNF-α and downregulation of survivin and mutant p53.
... damage is one of the molecular events associated with cell cycle arrest and ...shown to induce DNA damage [29,30]. Moreover, cancer cells are reported to be more ... See full document
14
Distinct Clinicopathological Patterns of Mismatch Repair Status in Colorectal Cancer Stratified by KRAS Mutations.
... tumors with KRAS mutation demonstrated more positive lymph nodes and pTNM III-IV stage of dis- ease than tumors with KRAS(-)/pMMR ...This is consistent with findings from a smaller report, ... See full document
12
Photocytotoxicity of a 5-nitrofuran- ethenyl-quinoline antiseptic (Quinifuryl) to P388 mouse leukemia cells
... Latvia, with the aim of develop- ing new antitumor ...toxicity to various lines of cancer cells (10,11), with Quinifuryl pos- sessing the highest cytotoxic activity (10) and showing ... See full document
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