[PDF] Top 20 Unraveling the function of CD11B+ myeloid cells in the tumor microenvironment
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Unraveling the function of CD11B+ myeloid cells in the tumor microenvironment
... and in the beginning this was easily explained by an attempt of the body to fight the cancerous cells, as explained by Burnet and Thomas in their cancer immune ... See full document
90
CXCL17 expression by tumor cells recruits CD11b+Gr1 high F4/80- cells and promotes tumor progression.
... promoters of tumor angiogen- esis [4,6]. In humans, a specific marker that will unequivocally identify MDSC has yet to be identified, and this population has not been defined in a uniform ... See full document
11
Contribution of ER stress to tumor immunosuppressive microenvironment
... dendritic cells are of most importance in the development of anti- tumor ...among the organism and play crucial roles in driving adaptive immune responses and ... See full document
88
Prognostic Value of CD11b Expression Level for Acute Myeloid Leukemia Patients: A Meta-Analysis.
... Cluster of differentiation 11b (CD11b) is a kind of cell surface receptor that are selectively expressed on leukocytes, which is also named as integrin alpha M (ITGAM), complement com- ponent 3 ... See full document
14
In silico experimentation of glioma microenvironment development and anti-tumor therapy.
... about the identities and biochemical activities of signaling molecules in the glioma microenvironment [1,2,3,4,5,44,45], how these mediators coordinate and function collectively ... See full document
10
Colorectal tumor microenvironment: unravelling the interplay between macrophages and the extracellular matrix
... with the infiltration of cells involved in chronic inflammation, high number of lymphocytes, namely T cells (CD3 + ), cytotoxic T cells (CD8 + ), or memory T cells ... See full document
178
TNF- a Regulates the Effects of Irradiation in the Mouse Bone Marrow Microenvironment
... showed the irradiation protocol induces loss of microsatellite markers by BM cells, suggesting it had carcinogenic/transforming capacity (Supplementary Figure ...Concerning the haematological ... See full document
12
CD11b(-)CD27(-) NK cells are associated with the progression of lung carcinoma.
... NK cells are the predominant NK-cell subpopulation that accumulates within the tumour ...performed in an early-developing murine MCA205 fibrosarcoma tumour model [34]. The impact ... See full document
11
Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model.
... Moreover, the data obtained from our co-culture suggests a potent modulatory effect on cancer-associated fibroblasts that will have a broad impact on tumor ...Therefore, the changes in ... See full document
13
The role of the hypoxic microenvironment on the macrophagetumor cell interplay
... effect of hypoxia on both tumor progression (Kim et ...explored the macrophage-cancer cells crosstalk as established under hypoxic conditions (Tripathi et ...several in vitro studies ... See full document
88
Crosstalk between immunosuppressive myeloid and effector lymphoid cells in the tumour microenvironment
... laboratory, in an ovarian ID8 model, IL-17 + Vγ6 γδ T cells can promote recruitment of small peritoneal macrophages (SPM: CD11b + F4/80 int ) that, in turn, lead to increased tumour ... See full document
73
STAT3 as a Key Factor in Tumor Microenvironment and Cancer Stem Cell
... that tumor-associated macrophages (TAMs) play a decisive role in the regulation of tumor progression by manipulating tumor oncogenesis, angiogenesis and immune functions within ... See full document
1
Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells
... weekly in P100 plates (BD Biosciences, Mis- sissauga, ON, CA) with fresh media containing either 5 µM of the telomerase inhibitor Imetelstat (Geron, Menlo Park, CA, USA) or scrambled mismatch ... See full document
15
The hemodynamically-regulated vascular microenvironment promotes migration of the steroidogenic tissue during its interaction with chromaffin cells in the zebrafish embryo.
... as the heart rate was accelerated by norepinephrine treatment from 33 hpf, a significant enhancement of interrenal tissue extension was detected at 2 dpf (Figure 2E-E’’, F-F’’, G-G’’, ...accelerated ... See full document
16
Estimation of the fraction of cancer cells in a tumor DNA sample using DNA methylation.
... Contamination of normal cells is almost always present in tumor samples and affects their molecular ...estimate the fraction of cancer cells in a tumor DNA ... See full document
10
Integration of stimulatory and inhibitory signals in pituitary tumor cells through the PI3K pathway
... Degree in Molecular and Oncology Medicine 29 indicates that MtT-S cells are able to express homodimeric PDGF- αα and – ββ receptors as well as the heterodimeric PDGF- αβ ...Thus, the ... See full document
59
Impact of P-cadherin expression in the modulation of E-cadherin adhesive function in cancer cells
... live cells, at 25°C, in serum free ...Japan). The softest triangular cantilevers, with a tip radius of 15 nm and a resonant frequency of 11 kHz, were ...used. The spring ... See full document
99
Correction: Conserved Molecular Underpinnings and Characterization of a Role for Caveolin-1 in the Tumor Microenvironment of Mature T-Cell Lymphomas.
... This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, prov[r] ... See full document
2
Elucidation of the molecular mechanisms underlying the cytotoxic effect of recombinant frutalin in human tumor cells
... expression of frutalin in ...observed in SDS-PAGE and according to Oliveira et al. [31], the molecular weight obtained on SDS-PAGE confirming that the expression of frutalin ... See full document
82
Unraveling the global microRNAome responses to ionizing radiation in human embryonic stem cells.
... that in mammals the primary mode of miRNA- mediated gene repression is through inhibition of translation, not direct mRNA target degradation ...explain the lack of downregulation ... See full document
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