[PDF] Top 20 Variation in protein expression levels in cell populations
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Variation in protein expression levels in cell populations
... made in an early work using human T cell clones, which argued for the number of TCR triggered upon stimulation as a threshold for the acquisition of certain effector functions (Viola and Lanzavecchia, ... See full document
214
Effects of propofol on lipopolysaccharide-induced expression and release of HMGB1 in macrophages
... anesthesia in clinical ...anesthetic in critical patients in the ...heart in patients with surgery (25), has the potential to treat sepsis (26,27), and can protect important organs in ... See full document
6
A DNA enzyme targeting Egr-1 inhibits rat vascular smooth muscle cell proliferation by down-regulation of cyclin D1 and TGF-β1
... the in- jured vessel, their hyperproliferation and their migration to the intima play a key role in lesion formation ...the expression of multiple proliferation-associated genes (6,7), and Egr-1 ... See full document
9
A phthalide derivative isolated from endophytic fungi Pestalotiopsis photiniae induces G1 cell cycle arrest and apoptosis in human HeLa cells
... observed in DAPI-stained HeLa cells. Flow cytometry showed that MP induced G1 cell cycle arrest and apoptosis in a dose-dependent ...investigate protein and mRNA expression. MP caused ... See full document
7
Long-time treatment by low-dose N-acetyl-L-cysteine enhances proinflammatory cytokine expressions in LPS-stimulated macrophages.
... p53 expression plasmid. In the result, removal of DOX from the media, that decreased p53 expression, increased IL-1b and IL-6 expressions in Figure ...The cell lysates were subjected to ... See full document
10
Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor.
... heterologous expression of epitope-tagged GPCR is widely adopted for functional characterization, there is lacking of systematic analysis of the impact of expression host and epitope tag on GPCR ...host ... See full document
14
Low expression of miR-196b enhances the expression of BCR-ABL1 and HOXA9 oncogenes in chronic myeloid leukemogenesis.
... the expression of miR-196b reduced BCR-ABL1 and HOXA9 protein levels (Figure ...decrease in the cell proliferation rate (Figure 3B, Table 3) and retardation of the G2 stage (Figure ... See full document
8
Evidence that RASSF1C stimulation of lung cancer cell proliferation depends on IGFBP-5 and PIWIL1 expression levels.
... IGFBP-5, in human mesenchymal stem cells [18]. Previous work in our laboratory has demonstrated that RASSF1C binds to IGFBP-5 and may regulate osteosarcoma cell proliferation and apoptosis ...gene ... See full document
10
Experimental DNA - or RNA-Directed therapies for Trinucleotide Repeat Disease
... reduce levels of mutant huntingtin protein in HD animal ...finger protein chains, designed to bind longer CAG-repeats more strongly than shorter repeats, in an HD mouse ...stable ... See full document
14
Enhancement of auranofin-induced apoptosis in MCF-7 human breast cells by selenocystine, a synergistic inhibitor of thioredoxin reductase.
... role in cancer cell apoptosis induced by anticancer drugs that cause DNA damage in the cell ...[13,14]. In our previous studies, SeC- induced apoptosis in cancer cells have been ... See full document
14
Tissue transglutaminase (TG2) activity regulates osteoblast differentiation and mineralization in the SAOS-2 cell line
... the expression, function and modulating mechanism of TG2 during osteoblast differentiation and ...osteosarcoma cell line SAOS-2 with osteo-inductive conditioned medium and set up three time points (culture ... See full document
9
Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia.
... role in cell cycle regulation ...retinoblastoma protein (Rb), a tumor suppressor that prevents excessive cellular division ...Serpinb2 expression to surprisingly high levels (up to ... See full document
18
Alterações nas proteínas de fissão e fusão mitocondriais, caspase 3 e sinaptofisina cerebrais induzidas pela sobrecarga de ferro neonatal : reversão pelo tratamento com canabidiol
... accumulation in the brain has been observed in both normal aging and in several neurodegenerative ...results in persistent memory deficits, which are accompanied by oxidative ...present ... See full document
84
Prostate stromal cells express the progesterone receptor to control cancer cell mobility.
... gene expression, we transiently transfected prostate stromal cells with siRNA against PR ...mRNA levels. In addition, PR exerted its inhibitory effects directly to SDF-1 and IL-6 gene transcription ... See full document
13
Population-specific regulation of Chmp2b by Lbx1 during onset of synaptogenesis in lateral association interneurons.
... yeast protein complex that creates the intralumenal vesicles of multivesicular ...mutations in Chmp2b cause autophagosome accumulation and neurodegen- erative ...maturation in cultured neurons. The ... See full document
17
Characterization of MTAP Gene Expression in Breast Cancer Patients and Cell Lines.
... CDKN2A in this cell line but not a deletion of CDKN2B or INK4A genes, which are closely located on the ...expressed in MCF-7 cells due to DNA ...mRNA expression but no evidence of ... See full document
13
BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION
... compromised in human triple-negative breast cancer. In the present study, we investigated the expression of PTPN12 protein by patients with breast cancer in a Chinese population and the ... See full document
8
Transcription factor Oct1 is a somatic and cancer stem cell determinant.
... Oct1 expression in frozen human colon sections using indirect immunofluorescence ...Oct6 in control experiments (Figure ...one cell removed from the lumen but clearly within the basement ... See full document
14
The HIV-1 Vpu viroporin inhibitor BIT225 does not affect Vpu-mediated tetherin antagonism.
... tetherin cell surface downregulation was performed by flow cytometry ...tetherin expression in SupT1-tetherin pos cells and SupT1-tetherin hTMa1 and to specifically detect cell surface ... See full document
8
The Role of Heat Shock Protein 90B1 in Patients with Polycystic Ovary Syndrome.
... the expression and activity of which are highly regulated by the extracellular ...gene expression and activity by affect- ing protein folding and ...Their expression levels ... See full document
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