Experimental DNA - or RNA-Directed therapies for Trinucleotide Repeat Disease

Summarizing, we have demonstrated in mice treated with MPTP that TUDCA administration increases Nrf2 expression levels, culminating in an increase in both protein and

However, as is the case for MyD88, the introduction of miR-124 mimic and inhibitor resulted in a respectively decreased and increased expression of TRAF6 at both mRNA and protein

Thus, we have demonstrated specific siRNA-directed knock- down of the TLR2 gene in the human hepatocellular carcinoma cell line BEL-7402, and shown that sh-TLR2 RNAi(B) was the

Crosstalk between Parkinson’s and Huntington’s diseases: α -synuclein modifies mutant huntingtin aggregation and neurotoxicity in Drosophila 4.1.. Co- expression of mutant

Two promising approaches to synthesiz- ing DNA/RNA aptamers directed against cell-adhesion molecules will be reviewed: RNA and DNA aptamers directed against L- and P-selectins and

Immunohistochemical studies in both embryonic mouse and chicken hearts, using antibodies directed against the N- or C-terminal of β2 integrin or against its α subunit partners,

mRNA and protein levels remain constant throughout the differentiation program in MC3T3-E1 cells, we found that in this human osteoblast cell line, the expression of TG2 protein

Results: Transfection of a MyoD saRNA (dsMyoD) into ADSCs significantly induced the expression of MyoD at both the mRNA and protein levels, and inhibited cell prolifera- tion..