• Nenhum resultado encontrado

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton.

N/A
N/A
Protected

Academic year: 2017

Share "Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton."

Copied!
17
0
0

Texto

Imagem

Figure 5. Sonic hedgehog signaling defect in Wdpcp Cys40 mutant. (A–F) In-situ hybridization of E10.5 forelimbs shows Wdpcp Cys40 mutants with expanded expression of Fgf4 in the AER (apical ectodermal ridge) (A, B) and Gremlin in the limb mesenchyme (C, D)
Figure 6. Wdpcp Cys40 mutants show PCP defects and disrupted canonical Wnt signaling. (A–D) Scanning EM of cochlear hair cells showed chevron-shaped stereocilia pointing laterally in control (A, C), but in Wdpcp Cys40 mutants, the stereocilia point in vary
Figure 10. Wdpcp deficiency disrupts polarized cell migration. (A–D) In a wound healing assay, control MEFs (A) were well aligned with the direction of wound closure (indicated by white arrow)

Referências

Documentos relacionados

The structure of the remelting zone of the steel C90 steel be- fore conventional tempering consitute cells, dendritic cells, sur- rounded with the cementite, inside of

social assistance. The protection of jobs within some enterprises, cooperatives, forms of economical associations, constitute an efficient social policy, totally different from

Taken together, our data suggest that G β regulates the strength of coupling between actin oscillators for efficient polarity and directional migration.. As these observa- tions

The probability of attending school four our group of interest in this region increased by 6.5 percentage points after the expansion of the Bolsa Família program in 2007 and

So, does this mean that if we block the activity of caspases we will prevent every sign of apoptosis and therefore keep the cells alive? The answer is yes in two situations: a)

In the developing quail retina model, the chronology of entry and tangential migration of ameboid microglial cells is highly coincident with that of cell death in the ganglion

Three quantities needed to judge the performance of the Rabifier are shown for Rabs belonging to human and other subfamilies separately: sequences erroneously classified as not being

– Bloco de Natação ter contribuído para “publicitar” as respetivas piscinas, pelo facto destas serem um pouco resguardadas e não estarem à vista da população; também o facto