alveolar macrophages
Mycobacterium tuberculosis expressing phospholipase C subverts PGE(2) synthesis and induces necrosis in alveolar macrophages
... Pulmonary macrophages are the primary niches for Mtb replication, thus host resistance is critically dependent on innate immune functions played by these ...by alveolar macro- phages than the isolate ...
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Response activity of alveolar macrophages in pulmonary dysfunction caused by Leptospira infection
... as alveolar cells ...of alveolar macrophages was not clear in the case reported by Yang & Hsu (16), who suggested that an immune-mediated destruction of the alveolar-endothelial tissue may ...
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Cigarette smoking decreases global microRNA expression in human alveolar macrophages.
... in alveolar macrophages of cigarette smokers and ...from alveolar macrophages as template in GeneChip Human Exon ...from alveolar macrophages directly isolated from four ...
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Increased iron sequestration in alveolar macrophages in chronic obstructive pulmonary disease.
... by alveolar macrophages in COPD lungs, and may represent a protective maneuver intended to control free iron, and therefore, perverse effects of ...by alveolar macrophages decresease the ...
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Acute Kidney Injury Reduces Phagocytic and Microbicidal Capacities of Alveolar Macrophages
... by macrophages [29], apoptotic neutrophils [30], and increased phagocytosis of ...the macrophages of rats sensitised and challenged with ovalbumin aerosol had an increased capacity of phagocytosis of IgG- ...
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Experimental murine mycobacteriosis: evaluation of the functional activity of alveolar macrophages in thalidomide- treated mice
... by the respiratory route. Thirty animals received daily thalidomide (30 mg/kg mouse) and 30 received water by gavage up to sacrifice. Ten non-inoculated mice were used as a control group. Lots of animals from each group ...
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The effects of Eucheuma cottonii on alveolar macrophages and malondialdehyde levels in bronchoalveolar lavage fluid in chronically particulate matter 10 coal dust-exposed rats
... acute alveolar and interstitial inflammation leading to chronic pulmonary ...lung macrophages has been reported to be the primary lung response to air pollutants in animal and ...human. Alveolar ...
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Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns.
... Alveolar macrophages (AMs) phagocytose Bacillus anthracis following inhalation and induce the production of pro- inflammatory cytokines and chemokines to mediate the activation of innate ...
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Leukotrienes Produced in Allergic Lung Inflammation Activate Alveolar Macrophages
... It has been well-documented that leukotrienes (LTs) are released in allergic lung inflammation and that they participate in the physiopathology of asthma. A role for LTs in innate immunity has recently emerged: Cys-LTs ...
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Resident alveolar macrophages are susceptible to and permissive of Coxiella burnetii infection.
... Interestingly, with NMI infection we were able to isolate bacterial DNA from the spleens of infected BALB/c mice. At day 9 PI, there was a significant increase in splenic bacterial burden for the 1610 3 NMI group, ...
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CDA-2, a urinary preparation, inhibits lung cancer development through the suppression of NF-kappaB activation in myeloid cell.
... in alveolar macrophages of tumor bearing mice and especially decreased the release of inflammatory factors including TNFa, IL-6, and ...bone-marrow-derived macrophages (BMDM) of mice stimulated by ...
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Histopathological and ultrastructural aspects of mice lungs experimentally infected with dengue virus serotype 2
... In our studies the histological analysis of lung tis- sues revealed interstitial pneumonia associated with vas- cular congestion, rare focal zones of parenquimal haemorrhage, increase of alveolar ...
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New insights into the anti-inflammatory actions of aspirin- induction of nitric oxide through the generation of epi-lipoxins
... bradykinin, play a role in oedema formation and contrib- ute to pain but are not generally considered to be chemo- attractant for leukocytes (Williams et al. 1988). Within the eicosanoid family, this is the ...
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Long-term exposure to cigarette smoke impairs lung function and increases HMGB-1 expression in mice
... Our results indicate that in mice there is an association between CS-induced emphysema and increased pulmonary HMGB- 1 expression (Fig. 3), primarily related to alveolar macrophages. Although the study does ...
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Early host cell targets of Yersinia pestis during primary pneumonic plague.
... As alveolar macrophages and neutrophils are the primary targets of ...of alveolar macrophages had little or no effect on bacterial burden in the ...either macrophages are not involved ...
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Role of matrix metalloproteinases in the development of airway inflammation and remodeling
... on alveolar macrophages col- lected from COPD patients have shown their ability to degrade more elastin than macro- phages collected from healthy volunteers ...
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J. Bras. Patol. Med. Lab. vol.48 número1
... The patient was admitted in our hospital to investigate fever and dry cough that initiates one month earlier. The physical examination was unremarkable. CT chest revealing a diffuse GGO pattern and bronchoscope was ...
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CD103+ Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans.
... Since pDCs are a major source of IFN-I during viral and bacterial infections [31], it was sur- prising that we detected no IFNβ production from pDCs in Histoplasma-infected lungs. To confirm that CD103 + cDCs but not ...
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J. Bras. Patol. Med. Lab. vol.49 número2
... exclusively alveolar macrophages, MSSA and MRSA, as described ...of alveolar macrophages, which contained MA and 10 µl of LPS (Escherichia coli serotype; 055:B5, Sigma ® ...
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J. Bras. Patol. Med. Lab. vol.42 número1
... Objectives: It has been experimentally demonstrated that host defense against Pneumocystis carinii depends on complex interactions within host immune response, mainly CD4 lymphocytes and alveolar ...
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