Antifungal agents
Candida tropicalis biofilms response to antifungal agents
... commercial antifungal agents: Fluconazole (Flu; Pfizer, New York, USA) and Voriconazole (Vcz; Pfizer, New York, USA) using the microdilution method, in accordance with the guidelines of the European ...
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Synthesis and preliminary evaluation of N-acylhydrazone compounds as antibacterial and antifungal agents.
... SYNTHESIS AND PRELIMINARY EVALUATION OF N-ACYLHYDRAZONE COMPOUNDS AS ANTIBACTERIAL AND ANTIFUNGAL AGENTS. We describe the synthesis and evaluation of N-acylhydrazone compounds bearing different electron- ...
4
Susceptibility variation of Malassezia pachydermatis to antifungal agents according to isolate source
... azole antifungal agents. In the case of polyene antifungal agents, the re- duced susceptibility of the G1 isolates may be related to the high activity of fungal intracellular enzymes such as ...
4
Sporothrix schenckii COMPLEX: SUSCEPTIBILITIES TO COMBINED ANTIFUNGAL AGENTS AND CHARACTERIZATION OF ENZYMATIC PROFILES
... overcome antifungal resistance and toxicity from monotherapy with AMB, antifungal combinations represent an alternative approach to enhance the efficacy of individual drugs and lower dosages; these combined ...
6
Inhibitors of the glyoxylate cycle enzyme ICL1 in Candida albicans for potential use as antifungal agents.
... of antifungal drugs to treat candidiasis are ...novel antifungal drugs with no significant side effects on patients continues, and research has been focused mainly on specific cell components and pathways, ...
8
In vitro susceptibility to antifungal agents of environmental Cryptococcus spp. isolated in the city of Ribeirão Preto, São Paulo, Brazil
... Most strains were resistant in vitro to 5-fluorocytosine, the drug with the highest MIC 50 for all strains tested. Furthermore, clinical use of 5-fluorocytosine in the treat- ment of C. neoformans infections has been ...
5
Genotyping of the MTL loci and susceptibility to two antifungal agents of Candida glabrata clinical isolates
... The opportunistic fungal pathogen Candida glabrata is the second most common isolate from bloodstream in- fections worldwide and is naturally less susceptible to the antifungal drug fluconazole than other Candida ...
8
Quantitative structure-activity relationship of some 1-benzylbenzimidazole derivatives as antifungal agents
... Quantitative structure-activity relationship (QSAR) has been used to study the relationships between the antifungal activity and lipophilicity parameter, logP, calculated by using CS C[r] ...
9
Rev. Soc. Bras. Med. Trop. vol.46 número3
... azole antifungal agents in Intensive Care Unit (ICU) and non-ICU settings in the SENTRY Antimicrobial Surveillance Program ...Antimicrob Agents 2011; ...
5
Genetic diversity and antifungal susceptibility profiles in causative agents of sporotrichosis
... Spontaneous cure, as well as relapse, are common fea- tures of sporotrichosis. Our present data show that most antifungal agents had only a fungistatic effect against clinical isolates. It remains unclear ...
9
Effect of farnesol on growth, ergosterol biosynthesis, and cell permeability in Coccidioides posadasii
... Ergosterol quantification. The results showed that the expo- sure of the 10 strains of C. posadasii to subinhibitory concentra- tions of farnesol altered the amount of ergosterol extracted from each sampled strain. ...
4
Defensins: antifungal lessons from eukaryotes
... of antifungal pep- tides have been reported, such as binding to the cell wall, membrane permeabilization, receptor-mediated internalization inducing signaling cascades, and interaction with intracellular tar- ...
17
Effects of piperonal nitro derivatives on candida species : antifungal activity against fluconazole resistant strains is associated with oxidative DNA damage
... of antifungal agents, mainly because of their natural coexistence with fungi present in each ...the antifungal effect of piperonal nitro derivatives (PNDs) in Candida ...the antifungal effect ...
16
Antimicrobial activity of Pterogyne nitens Tul., Fabaceae, against opportunistic fungi
... ABSTRACT: As part of our ongoing research on antifungal agents from Brazilian flora, eight extracts and twelve fractions from Pterogyne nitens Tul., Fabaceae, were screened for antimicrobial activity ...
6
Síntese de complexos de rutênio binucleares com ligantes ditiocarbamatos e avaliação in vitro da citoxidade e atividade antifúngica contra fungos de interesse clínico
... These ruthenium dithiocarbamate complexes ( 1-5 ) were studied as novel antifungal agents against five different Candida species ( C. tropicalis ), these data were compared[r] ...
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Rev. Soc. Bras. Med. Trop. vol.46 número2
... Clinical and Laboratory Standards Institute (CLSI) developed a document in 2006, classiied as M27-A2, which describes the ranges and breakpoints of the antifungal agents used to treat invasive fungal ...
2
ENVIRONMENTAL STRAINS OF Cryptococcus neoformans VARIETY grubii IN THE CITY OF SANTOS, SP, BRAZIL
... the antifungal agents 5-fluorocytosine, fluconazole, itraconazole, amphotericin B and voriconazole, by means of the microdilution method (EUCAST), we point out that one sample demonstrated resistance to ...
6
NR Melo+ , H Taguchi, J Jorge, RJ Pedro, OP Almeida, K Fukushima, K Nishimura, M Miyaji
... Since the human immunodeficiency virus (HIV) was described in the 1980s, the number of HIV-infected pa- tients has continued to increase and at present over than 50 million patients have been documented in the world. ...
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MATERIALS AND METHODS Isolates
... Recently Ribeiro (28) isolated nine C. neoformans var. neoformans (serotype D) strains from 99 samples of Eucalyptus spp. As pointed out by Martinez et al. (21), the thermal sensibility of C. neoformans var. neoformans ...
6
Braz. oral res. vol.21 número1
... Abstract: The aim of this study was to evaluate the adherence capability to HeLa cells, the susceptibility to killer toxins and the in vitro susceptibility to antifungal agents (eTest method – AB Biodisk, ...
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