C-TERMINAL DOMAIN
Adaptive Immunity against Leishmania Nucleoside Hydrolase Maps Its C-Terminal Domain as the Target of the CD4+ T Cell-Driven Protective Response
... the domain of the NH of ...its C-terminal domain (amino-acids 199–314) and is mediated mainly by a CD4+ T cell driven response with a lower contribution of CD8+ T ...the C-domain ...
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Aquareovirus NS80 recruits viral proteins to its inclusions, and its C-terminal domain is the primary driving force for viral inclusion formation.
... NS C- terminus, including two coiled-coil structures, the intercoil linker region, and the C-terminal tail, are key elements required for inclusion activity ...
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Regulation of abiotic stress signalling by Arabidopsis C-terminal domain phosphatase-like 1 requires interaction with a k-homology domain-containing protein.
... the domain structures of wild type and variant ...homology domain; dsRBM, double-stranded RNA-binding motif; N C , C-terminal NLS; 3xFLAG, 3xFLAG-tag; ...
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A structural perspective on the mechanisms of quorum sensing activation in bacteria
... N-terminal domain that binds the AI and a C-terminal domain that recognizes specific DNA ...each domain of LuxR-type receptors presents different relative ...each domain ...
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Functional Domains of the Bacillus subtilis Transcription Factor AraR and Identification of Amino Acids Important for Nucleoprotein Complex Assembly and Effector Binding†
... N-terminal domain of FadR, the DNA-bound and DNA-free conformations are substantially different, even in the C-terminal domain (which does not contact ...the C-terminal ...
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Mre11 assembles linear DNA fragments into DNA damage signaling complexes.
... What differentiates the essential function of Mre11 during DNA replication from its ability to activate ATM? We suggest that MRN association with chromatin during DNA replica- tion and, possibly, during meiotic ...
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Mechanism of the interaction between the intrinsically disordered C-terminus of the pro-apoptotic ARTS protein and the Bir3 domain of XIAP.
... gene. Domain characterization of Sept4 [35,36] describes three major domains including the N-terminal domain (residues 1–119), a GTPase domain (residues 144–416) and a C-terminal ...
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Flexible 3D structure of Bos taurus tyrosyl-tRNA synthetase suggests the existence of hinge mechanism provided by conservative Gly353 at interdomain linker
... of C-domains guided by pre- dicted secondary structure revealed two independent sub- domains (folds): a b-pleated Myf domain (OB-fold, re- sidues Val363-Lys470) and a-helical sub-domain (re- sidues ...
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The subfamily-specific interaction between Kv2.1 and Kv6.4 subunits is determined by interactions between the N- and C-termini.
... the C-terminus of ...the C-terminus of ...Kv6.4 C-terminus should also disturb the assembly of ...Kv6.4 C-terminus was replaced by the C-terminal domain of ...
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Mycobacterial laminin-binding histone-like protein mediates collagen-dependent cytoadherence
... When grown in the presence of exogenous collagen I, Mycobacterium bovis BCG was shown to form clumps. Scanning electron microscopy examination of these clumps revealed the presence of collagen fibres cross-linking the ...
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Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster.
... At the structural level, much is known about CSL and the activator complex it forms with NICD and MAM [8–12]. As shown in Fig 1B, the structure of CSL consists of three domains: NTD (N-terminal domain), BTD ...
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Cell division and chromosome segregation in
... transmembrane domain, the localization at the septum most likely requires a direct interaction with a divisome ...its C-terminal domain, causes only mild segregation ...Its ...
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The carboxyl-terminus of human immunodeficiency virus type 2 circulating recombinant form 01_AB capsid protein affects sensitivity to human TRIM5α.
... N-terminal domain of CA, we found that HIV-2 CRF01_AB-specific amino acid substitutions in the C-terminal domain also were necessary for resistance to human ...the ...
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The Herpes Simplex Virus Neurovirulence Factor γ34.5: Revealing Virus-Host Interactions.
... a C-terminal domain that retargets the host phosphatase PP1α to eIF2α for dephosphorylation and reversal of host cell-mediated translational ...
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Schistosoma mansoni Polo-like kinases and their function in control of mitosis and parasite reproduction
... kinase domain, SmSak was more identical to Plk4 members than to SmPlk1, indicating that SmSak was a second schistosome Plk belonging to the group 4 of the Plk ...the C-terminal domain of SmSak ...
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N-terminal domain of turkey pancreatic lipase is active on long chain triacylglycerols and stabilized by colipase.
... N-terminal domain (N-TPL), fused with a His6-tag, was cloned and expressed in Pichia pastoris, under the control of the glyceraldehyde-3-phosphate dehydrogenase (GAP) constitutive ...this domain was ...
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Evolution and structural organization of the C proteins of paramyxovirinae.
... and C, which overlaps ...The C proteins cluster in three groups, comprising measles, Nipah, and Sendai ...all C proteins have a similar organization: a variable, disordered N-terminus and a ...
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The minimal autoinhibited unit of the guanine nucleotide exchange factor intersectin.
... (DH) domain guanine nucleotide exchange factors (GEF) which control Rho- family GTPase ...DH domain shows high ...fifth domain (SH3(E)) being sufficient for the bulk of the autoinhibitory ...SH3 ...
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Two coiled-coil domains of Chlamydia trachomatis IncA affect membrane fusion events during infection.
... proteins. Domain swap and deletion experiments revealed that although both these domains are capable of independently inhibiting SNARE-mediated fusion, these two coiled-coil domains cooperate in mediating IncA ...
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Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence.
... NA domain sedimented as a dimer and the HN C596S NA domain sedimented as a ...NA domain is observed mostly as dimers (Figure 3C, left) whereas the HN C596S mutant is observed mostly as monomers ...
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