cell cycle G1 phase
Cell proliferation and migration are modulated by Cdk-1-phosphorylated endothelial-monocyte activating polypeptide II.
... proliferating cell populations, stable clonal A549 cell populations that overexpressed EMAP II protein (pFEII-GFP) or an empty vector (pEGFP-N3) were established using antibiotic pressure selection (WB of ...
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LncRNA HULC mediates radioresistance via autophagy in prostate cancer cells
... rate, cell apoptosis, cycle, expressions of related proteins, and caspase-3 activity were assessed to explore the effects of HULC on sensitivity of PCa cells to ...and cell cycle were ...
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Undecylprodigiosin induced apoptosis in P388 cancer cells is associated with its binding to ribosome.
... cancer cell growth has been known to be primarily mediated by apoptosis and cell cycle ...analyze cell cycle phase distribution and apoptosis upon UP ...G0/G1 phase ...
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Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle.
... Mammalian DNA replication starts at distinct chromosomal sites in a tissue-specific pattern coordinated with transcription, but previous studies have not yet identified a chromatin modification that correlates with the ...
14
Rev. bras. farmacogn. vol.25 número3
... cancer cell proliferation and inhibits the growth of transplanted tumor xenografts by inducing apoptosis and/or by blocking abnormal cell cycle progression at the G1 or G2/M phase (Riou ...
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The effect of the G1-S transition checkpoint on an age structured cell cycle model.
... the cycle in a group this would result in the phase distribution being ...the cell population was ...in phase distributions obtained from such experiments as the timing of observations would ...
9
Bioluminescence imaging of DNA synthetic phase of cell cycle in living animals.
... synthetic phase (S-phase) targeted anti-cancer drug activity in vitro; however, techniques for imaging of in vivo models remain ...during G1-phase, but they increase at the onset of ...of ...
10
AZD2014 Radiosensitizes Oral Squamous Cell Carcinoma by Inhibiting AKT/mTOR Axis and Inducing G1/G2/M Cell Cycle Arrest.
... controls cell cycle progression and cell proliferation by regulat- ing S6K1 and the eukaryotic translation initiation factor, ...cause cell cycle arrest [11,12], we assessed ...
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Identification of inhibitory mechanisms preventing CENP-A assembly in the S phase of the cell cycle
... the cell cycle to telophase/early G1 phase and is a consequence of low Cdk1 and Cdk2 ...Outside G1 phase, these kinases inhibit CENP-A assembly by acting on assembly factors ...
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Celastrol blocks interleukin-6 gene expression via downregulation of NF-κB in prostate carcinoma cells.
... the cell cycle at the G0/G1 phase, thus attenuating cell proliferation in prostate carcinoma PC-3 cells; moreover, celastrol induced cell apoptosis at higher ...PC-3 cell ...
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Adenovirus as a Biopharmaceutical
... the cell cycle duration as a result of the temporal dilation of the G1, S and M (mitosis) phases, with G2 being the least and M the most sensitive phases to temperature shift (Rieder and Cole, 2002), ...
200
Rev. bras. farmacogn. vol.22 número3
... tumor cell lines, show that the carvacrol is the most cytotoxic ...on cell cycle progression was examined by l ow cytometry after DNA staining in order to investigate the molecular mechanism of their ...
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FACT prevents the accumulation of free histones evicted from transcribed chromatin and a subsequent cell cycle delay in G1.
... in G1, independently of the histone synthesis that takes place during the S-phase, we incubated alpha factor-synchronized spt16-197 cells for two hours at either 25 uC or ...the cell if not targeted ...
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Pravastatin induces cell cycle arrest and decreased production of VEGF and bFGF in multiple myeloma cell line
... B cell bone marrow neoplasia characterized by inflammation with an intense secretion of growth factors that promote tumor growth, cell survival, migration and ...MM cell line.Cell cycle and ...
7
Growth Conditions and Cell Cycle Phase Modulate Phase Transition Temperatures in RBL-2H3 Derived Plasma Membrane Vesicles.
... average cell density over 15°C in transition temperature and nearly three orders of magnitude in average surface ...the G1/S border through a double Thymidine block and find that average transition ...
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A phthalide derivative isolated from endophytic fungi Pestalotiopsis photiniae induces G1 cell cycle arrest and apoptosis in human HeLa cells
... significant cell-cycle arrest in G1 phase. Cell cycle progression is controlled by a family of serine/threonine kinase holoenzyme complexes, composed of cyclins and ...
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Interaction of the retinoblastoma protein with Orc1 and its recruitment to human origins of DNA replication.
... the G1 phase CDKs, repression by Rb is relieved and transcription of the E2F-target genes ...couple cell cycle progression to the expression of genes that are required for DNA ...S ...
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Anticancer activity of lichen substances: a systematic review
... The molecular mechanisms associated with anticancer activity of lichen extracts is summarized in Table 5. Among the 296 species reported in the reviewed literature, 116 are cytotoxic, 46 have anti-apoptotic effects and ...
72
Ammonia Affects Astroglial Proliferation in Culture.
... on cell proliferation has been studied in enterocytes, kidney epithelial cells and nerve cells, but information regarding its effect on cell proliferation in astroglia is very scarce, and what there is can ...
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NOP14 inhibits melanoma proliferation and metastasis by regulating Wnt b-catenin signaling pathway
... Tumor progression is driven by molecular changes that confer proliferative advantage and promote invasive and metastatic phenotypes. Reports show that the Wnt/b- catenin pathway is important for embryonic development and ...
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