IMMUNE-RESPONSES
Lipid motif of a bacterial antigen mediates immune responses via TLR2 signaling.
... IgG1) immune responses [17–21]. Generation of skewed antibody responses elicited by non-lipidated rP6 probably reflect the contribution of the protein ...2 responses, although other groups ...
11
Understanding how dendritic cell glycans affect antitumor immune responses
... Alternatively, since the mid-90s, DCs have been used in clinical trials as cellular mediators for therapeutic vaccination of cancer patients (Anguille et al., 2014). The use of DCs in an immunotherapeutic strategy is ...
97
Immune responses to gp82 provide protection against mucosal Trypanosoma cruzi infection
... 1 immune responses - Systemic immuniza- tion with alum + gp82 has previously been shown to induce immune responses that were capable of reducing parasi- taemia after systemic MT challenge ...
5
Isotype Specific Immune Responses in Murine Experimental Toxocariasis
... isotype-specific immune responses against excretory-secretory antigens from ...subclass responses showed a similar profile in the three murine strains studied, with high values in BALB/c, as in the ...
6
Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease
... pathogenic immune responses during the chronic phase of the ...host’s immune response is decisive in this ...the immune response, it is becoming evident that the host genetic background plays ...
11
Variability in innate host immune responses to cryptococcosis
... Whilst therapeutic approaches for HIV-associated cryptococcal disease in combination with ARTs are successfully being established, efforts to determine pro- tective features of the innate immunity in non-HIV-as- sociated ...
5
The Imd pathway is involved in antiviral immune responses in Drosophila.
... innate immune system responds to a CrPV challenge, we measured humoral and cellular immune responses to viral ...humoral immune response in the fly involves the rapid transcriptional ...
9
Polysaccharides isolated from Acai fruit induce innate immune responses.
... innate immune system and modify host responses ...these immune responses are unknown and the optimal therapeutic potential of these materials is ...innate immune response to herbal ...
14
Immune responses accelerate ageing: proof-of-principle in an insect model.
... of immune responses become exacerbated under environmental stress [38] and hence any effect on the aging phenotype will be shifted forward in an individual’s lifespan and become subject to natural ...An ...
7
Predictive computational modeling of the mucosal immune responses during Helicobacter pylori infection.
... models. Interestingly, our simulations with the myeloid cell-specific PPARc knockout system promoted Th17 differentiation and suppressed Treg expansion. Considering that CD4+ T cells have a pivotal role and crosstalk ...
14
Characterising the mucosal and systemic immune responses to experimental human hookworm infection.
... The hookworms Necator americanus and Ancylostoma duodenale infect an estimated 740 million people, mostly in tropical regions of the world, causing significant burden of disease [1]. As for most Neglected Tropical ...
11
Vaccine-mediated immune responses to experimental pulmonary Cryptococcus gattii infection in mice.
... C. gattii is categorized into four genotypes: VGI, VGII, VGIII, and VGIV, based on multilocus sequence typing (MLST) [21]. The VGII genotype of C. gattii is further divided into three subtypes: VGIIa, VGIIb, and VGIIc. ...
13
The immune responses of the coral
... innate immune system of corals, as in all invertebrates, is responsible for maintaining the integrity and stability of the internal environment ...Adaptive immune-like systems have yet to be described in ...
10
Cellular immune responses to nine Mycobacterium tuberculosis vaccine candidates following intranasal vaccination.
... Interestingly, the frequency of antigen-specific cytokine-secret- ing cells found in the lymph nodes (CLNs and ILNs), a secondary lymphoid organ where immune responses develop, was low compared to that ...
14
Bacterial flagellin triggers cardiac innate immune responses and acute contractile dysfunction.
... The main characteristics of septic cardiomyopathy are depressed contractility, reduced LV ejection fraction and bi-ventricular dilation [7]. Recent studies have indicated that intrinsic alterations within cardiac ...
13
Role of α2-macroglobulin in the immune responses of invertebrates
... subsequent immune destruction. It will be interesting to determine if this functional characterization is universal amongst metazoans or whether there is functional diversity for members of the C3 family from ...
16
Breakdown of intestinal homeostasis by mucosal infections triggers adaptive immune responses against antigens from commensal bacteria
... the immune system, including the expansion and differentiation of splenic CD4 + T ...the immune-inducing effects of a complete conventional microbiota suggesting, unexpectedly, that only a restricted number ...
145
The immune system strikes back: cellular immune responses against indoleamine 2,3-dioxygenase.
... were immune- precipitated by using the HLA class I specific, conformation dependent monoclonal antibody (mAb) W6/32 and separated by isoelectric focusing (IEF) gel ...
11
Sistema imunitário - parte II: fundamentos da resposta imunológica mediada por linfócitos T e B
... the immune response in the eradication of pathogens and are also very important in the activation of BL, macrophages or even CD8 ...antiviral responses and also have anti-tumor ...the immune ...
15
Development of a Multivalent Subunit Vaccine against Tularemia Using Tobacco Mosaic Virus (TMV) Based Delivery System.
... When immune responses were compared between mice receiving TMV-monoconjugate and TMV-multiconjugate vaccine using a similar vaccination regimen (Schedule I), a weaker antibody response was observed in mice ...
22