late-onset Alzheimer’s disease
Association of apolipoprotein E polymorphism in late-onset Alzheimer's disease and vascular dementia in Brazilians
... and late-onset Alzheimer’s disease as well as in the general ...in late-onset Alzheimer’s disease (N = 68), other late-life dementias (N = 39), and in cognitively normal ...
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Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families.
... with disease, illustrating how phenocopies, potential presymptomatic individuals and reduced penetrance may compli- cate the interpretation of novel sequence variants in familial and sporadic ...of onset of ...
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SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
... Angeles, P50 AG016570; University of California, San Diego, P50 AG005131; University of California, San Francisco, P50 AG023501, P01 AG019724; University of Kentucky, P30 AG028383; University of Michigan, P50 AG008671; ...
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Strong evidence for a genetic contribution to late-onset Alzheimer's disease mortality: a population-based study.
... the disease is ...in late- as compared to early-onset ...to disease rather than an illness incident to aging, perhaps because of continuing societal ...
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The impact of Bridging Integrator 1 (BIN1) rare coding mutations on the development of Late-Onset Alzheimer’s Disease
... Furthermore, we should investigate whether the mutated BIN1 proteins lead to an accumulation of BACE1 in any of the endocytic compartment and if they lead to a disequilibrium between the amount of this BACE1 that is ...
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Meta-analysis for genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.
... Most GWAS analysis focused on individual SNPs have a stringent threshold for significance that must be applied due to the number of tests conducted in the study. It is possible that multiple variants can jointly ...
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Relationship between Adiponectin Gene Polymorphisms and Late-Onset Alzheimer's Disease.
... Subjects in the LOAD group were AD patients confirmed by the Neurology Department of the Third Xiangya Hospital of Central South University, China. The control group comprised healthy people receiving physical check-ups ...
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Investigation of five polymorphic DNA markers associated with late onset Alzheimer disease
... Alzheimer's disease is a complex neurodegenerative disorder characterized by memory and cognitive impairment and is the leading cause of dementia in the ...of late onset Alzheimer's disease in ...
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Recognizing Late Onset Frontotemporal Dementia with the DAPHNE scale
... The DAPHNE (an acronym for Disinhibition, Apathy, Perseverations, Hyperorality, Personal Neglect and loss of Empathy) is a six-domain, ten-item scale designed as a semi-structured interview. The first five domains were ...
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Regulation of Aß-scavengers in the choroid plexus of Alzheimer´s disease patients.
... Regarding the third objective, the results in this current work show, for the first time, the expression of the Aβ-scavengers TTR, GLS and NEP in the human CP. Transthyretin (TTR) mRNA expression levels were ...
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Prevalence of Late-Onset Pompe Disease in Portuguese Patients with Diaphragmatic Paralysis - DIPPER Study
... Patients were excluded from the study if they were unable or unwilling to provide informed consent, were tra- cheostomized or pregnant, required invasive mechanical ventilation, or suffered from one of the following con- ...
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Diagnosis Recommendations for Late-onset Pompe Disease
... Foi reunido um painel de especialistas com experiên- cia no diagnóstico e tratamento de várias formas de doen- ças metabólicas hereditárias e miopatias. Estes realizaram uma revisão da literatura através da pesquisa em ...
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Identification of probable early-onset biomarkers for tuberculosis disease progression.
... TB disease (progressors), versus contacts who remain healthy (non-progressors), allows for identification of predictive markers of TB ...the onset of active TB at a very early stage after ...
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L-threonine supplementation during colitis onset delays disease recovery
... specific amino acids that can improve intestinal homeostasis, mainly by boosting mucosal healing and regeneration. For instance, glutamine is known to promote protection in dextran sulfate sodium (DSS)- and ...
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Late-onset Radiologic Findings of Respiratory System Following Sulfur Mustard Exposure
... bronchiolitis obliterans, obstructive lung disease and lung cancer are manifestations of the chronic phase (6,7). SM toxicity can lead to acute lung injury (ALI) as well as acute respiratory distress syndrome ...
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Late onset Ito's nevus
... Nevus of Ito occurs most frequently in Asian popu- lations and the true incidence is unknown. 4 The majority of cases are diagnosed in early infancy and in early adolescence. 4 8 9 Few cases of acquired dermal ...
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Importância das vitaminas, antioxidantes e ómega-3 na Doença de Alzheimer : monografia : <<The>> role of vitamins, antioxidants and omega-3 in Alzheimer´s Disease
... De acordo com o descrito torna-se evidente a necessidade de realização de mais investigação no sentido de determinar medidas nutricionais seguras e úteis para a prevenção e tratamento da DA. Embora nada tenha sido ...
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Development and evaluation of a website with Alzheimer´s disease information and its consequences for communication
... Alzheimer’s disease and the consequences in the communication of the elderly were carried ...Alzheimer’s disease; The brain and Alzheimer’s disease; Signs and characteristics of Alzheimer’s ...
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Development and evaluation of a website with informations Alzheimer´s disease and its consequences for communication
... A fim de facilitar a legibilidade e acessibilidade do material, foi utilizado o Índice de Flesch, encontrando-se somente dois textos (de dois submenus) caracterizados como difíceis, sendo eles “Orientações ...
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[Anesthesia and Alzheimer disease - Current perceptions]
... O uso de modelos animais permite a explorac ¸ão dos mecanismos através dos quais os anestésicos possam estar envolvidos na patogenia da doenc ¸a de Alzheimer. Um estudo piloto nesta área, in vitro --- que usou um ...
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