Melanoma Cell Line
Inhibition of metastatic potential of B16F10 melanoma cell line in vivo and in vitro by bi fl orin
... for cell mi- gration and invasion because they mediate the adhesion of cells to the ECM and regulate intracellular signaling pathways that control cyto- skeletal organization, force generation, and survival (Zhou ...
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Chromosome instability in the murine melanoma cell line K-1735 is due to drug-specific mechanisms
... O objetivo do presente estudo foi investigar a instabilidade cromossômica e o reparo de DNA, expondo clones da linhagem celular de melanoma murino K-1735 à droga radiomimética bleomicina e ao inibidor da DNA ...
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Demonstration of a melanoma-specific CD44 alternative splicing pattern that remains qualitatively stable, but shows quantitative changes during tumour progression.
... in cell cultures from metastatic (newborn) and non-metastatic human xenograft model (Real-Time PCR measurement) of HT199, a human melanoma cell line of originally low variable exon expression ...
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Mining Gene Expression Signature for the Detection of Pre-Malignant Melanocytes and Early Melanomas with Risk for Metastasis
... non-metastatic melanoma cell counterpart: 112 up- and 51 down-regulated genes in 4C112 non-metastatic melanoma cell line when compared with 4C pre-malignant melanocyte lineage (stage II ...
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Nicotinamide inhibits vasculogenic mimicry, an alternative vascularization pathway observed in highly aggressive melanoma.
... aggressive melanoma cells is a novel form of tumor microcirculation pattern, which differs from classically described endothelium-dependent ...tumor cell plasticity displaying highly dedifferentiated ...
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FTY720 induces apoptosis in B16F10-NEX2 murine melanoma cells, limits metastatic development in vivo, and modulates the immune system
... murine melanoma cell line in C57BL/ 6 mice, was originally obtained from the Ludwig Institute for Cancer Research, Sa˜o Paulo ...tumor cell line, namely, low immuno- genicity and ...
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Bi-module sensing device to in situ quantitatively detect hydrogen peroxide released from migrating tumor cells.
... melanoma cell line. The HEp-2 cell line was originated from tumors, which were produced in irradiated-cortisonised weanling rats after injection of epidermoid carcinoma tissue isolated ...
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Mistletoe in the treatment of malignant melanoma
... lignant melanoma cells was demonstrated in vitro experiments ...inhibited melanoma cell proliferation in a dose-de- pendent manner starting at very low ML concentra- tions ...sensitive cell ...
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Effect of Modified Alkaline Supplementation on Syngenic Melanoma Growth in CB57/BL Mice.
... B16F10 melanoma cell line, receiv- ing alkaline supplementation by oral gavage as a daily single dose showed delayed tumor growth compared to controls (Fig ...
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BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
... erythroleukemia cell line ...cancer cell lines namely renal cancer, mammary cancer, melanoma cell line, among which chinikomycin A was potent than chinikomycin ...in cell ...
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A tumor-penetrating peptide modification enhances the antitumor activity of thymosin alpha 1.
... Meanwhile, cell adhesion analysis revealed that Ta1- iRGD exhibited more specific and greater binding with tumor cells compared with ...mouse melanoma cell line B16F10 and human lung cancer ...
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The calpain/calpastatin system has opposing roles in growth and metastatic dissemination of melanoma.
... promoting cell survival ...promote cell migration and invasiveness, which are essential features of tumor cells ...inducing cell apoptosis ...in cell death ...of melanoma as a tool to ...
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A new peptide ligand for targeting human carbonic anhydrase IX, identified through the phage display technology.
... renal cell carcinoma cell line SKRC 52, the human colorectal carcinoma cell line HCT 116, the CAIX negative human renal cell carcinoma cell line CaKi 2 and on human ...
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Phosphorylation and subcellular localization of p27Kip1 regulated by hydrogen peroxide modulation in cancer cells.
... with melanoma cells, showed decreased levels of Figure ...(blue line) and 1000 (orange line) U/ml catalase or left untreated (green line) for 24 ...(black line) and control cells ...
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J. Braz. Chem. Soc. vol.22 número8
... lymphoma cell line Daudi and myeloid cell line K562 were used for studying the effects of the synthesized mesoionic compounds on leukemic ...
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BRITER: a BMP responsive osteoblast reporter cell line.
... reporter cell line that will specifically report BMP signaling activity for the purpose of high-throughput functional genetic or chemical genetic screening of BMP signaling ...reporter cell ...
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Synthesis, cytotoxicity and mechanistic evaluation of 4oxoquinoline3carboxamide derivatives : finding new potential Aaticancer drugs
... 16. Voreloxin is not in the market (but in clinical trial) and literature still ask about its ability of replacing the anthracycline drugs, requesting future investigation to confirm its efficacy. Altogether these data ...
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Gene transfer and genome-wide insertional mutagenesis by retroviral transduction in fish stem cells.
... fish cell transduction: rvLegfp and rvLcherry produce green fluorescent protein (GFP) and mCherry fluorescent protein respectively under control of human cytomegalovirus immediate early promoter upon any ...
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In vitro and in vivo studies of pirarubicin-loaded SWNT for the
... cancer cell line BIU-87 and human myo- fibroblast cell line C2C-12 (both purchased from ShangHai cell bank, China) were cultured in RPMI 1640 medium (Hy- Clone, USA) with 10% fetal calf ...
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In vitro Anticancer Property of Yellow Pigment from Streptomyces griseoaurantiacus JUACT 01
... Despite a number of drawbacks, novel apoptosis triggering drugs/approaches will enhance the development of innovative strategies in cancer therapy. DNA fragmentation is one of the notable biochemical changes occurring ...
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