micronucleus test
Assessment of the mutagenic, antimutagenic and cytotoxic activities of ethanolic extract of araticum (Annona crassiflora Mart. 1841) by micronucleus test in mice
... A typical Brazilian plant, araticum (Annona crassiflora Mart.), is widely used in humans as therapeutic medicine to treat several diseases such as diarrhea, rheumatism and syphilis. It contains acetogenins which present ...
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Absence of antimutagenicity of Cochlospermum regium (Mart. and Schr.) Pilger 1924 by micronucleus test in mice
... The Micronucleus Test was performed in polychromatic erythrocytes from Swiss male mice treated with one of the four doses of extract of the plant (19, 38, 76 and 114 ...
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Teste de micronúcleo um importante biomarcador celular / Micronucleus test an important cell biomarker
... the Micronucleus (MN) test using exfoliated cells from the oral cavity is widely used in the biomonitoring of professionals exposed to environmental genotoxic agents and in the monitoring of pre-cancerous ...
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The bone marrow micronucleus test and metronidazole genotoxicity in different strains of mice ( Mus musculus)
... The micronucleus test is often used to predict the car- cinogenic potential of compounds (Sato et ...this test is continuously broadening by incorporating new technologies for the detection of ...
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Genotoxicity and mutagenicity of water contaminated with tannery effluents, as evaluated by the micronucleus test and comet assay using the fish Oreochromis niloticus and chromosome aberrations in onion root-tips
... as test organisms for the study of carcinogenesis and model systems based on fish have become important for determining the distribu- tion and toxic effects of aquatic contaminants, with in vivo techniques such as ...
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Allium cepa e teste do Micronúcleo como bioindicadores de citogenotoxicidade em extratos aquosos de plantas medicinais / Allium cepa and Micronucleus test as bioindicators of cytogenotoxicity in aqueous extracts of medicinal plants
... MN test are used for the initial screening for cytogenotoxicity of compounds present in aqueous plant ...Medicinal, Micronucleus Test and Allium ...
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Evaluation of the mutagenic effect of the iodinated contrast medium Urografi na ® 292 using the micronucleus test in mouse bone marrow cells
... The micronucleus assay was performed according to the US Environmental Protection Agency Gene- Tox Program (Mavournin et al. 1990). Bone marrow from both femurs was suspended in fetal calf serum and smears were ...
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Genotoxic and Antigenotoxic Assessment of Chios Mastic Oil by the In Vitro Micronucleus Test on Human Lymphocytes and the In Vivo Wing Somatic Test on Drosophila.
... All results of the CBMN assay are expressed as the mean frequency ± standard error (MF ± se). The G-test for independence on 2x2 tables was used to perform the statistical analysis of the MN data. The chi-square ...
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Rev. bras. farmacogn. vol.23 número2
... frequency micronucleus test animals treated with different substances is an indication of chromosomal damage induced (Krishna & Hayashi, ...the micronucleus test as a biomarker for ...
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Rodrigo dos Santos Rocha, José Roberto Cardoso Meireles and Eneida de Moraes Marcílio Cerqueira
... the micronucleus test was per- formed on exfoliated oral mucosa cells, in accordance with the protocols developed by Tolbert et ...this test is notably greater when the exposure to the mutagenic ...
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Assessment of the In Vivo Genotoxicity of New Lead Compounds to Treat Sickle Cell Disease
... a micronucleus test using mouse peripheral blood to identify new candidate drugs for the treatment of sickle cell disease (SCD) that are safer than ...
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Cytotoxicity and genotoxicity of Agaricus blazei methanolic extract fractions assessed using gene and chromosomal mutation assays
... cell micronucleus test showed an antigenotoxic effect of ...comet test using the same cells did not (Guterrez et ...cell micronucleus test indicated that 3:1 chloroform/methanol ...
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Rev. bras. farmacogn. vol.22 número2
... the micronucleus test was used to detect clastogenic/aneugenic activities, which leads to increasing micronucleus frequency, suggesting the occurrence of mutagenic effects at chromosomal level ...
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Mutagenicity and cytotoxicity in patients submitted to ionizing radiation A comparison between cone beam computed tomography and radiographs for orthodontic treatment
... Objectives: To evaluate and compare mutagenicity (micronucleus) and cytotoxicity (karyorrhexis, pyknosis, and karyolysis) in exfoliated buccal mucosa cells of children following cone beam computed tomography ...
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FLOW CYTOMETRY BASED MICRONUCLEUS ASSAY FOR EVALUATION OF GENOTOXIC POTENTIAL OF 2-ACBs IN HEPATIC CELLS HepG2
... the test recommended by the guide OECD 487 In vitro Mammalian Cell Micronucleus Test, the cell count as well as micronucleus is performed by light microscopy, or fluorescence-based microscopy ...
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Investigation on the Genotoxicity of Mercuric Chloride to Freshwater Clarias gariepinus
... small nucleus that is created from a lagging chromosome in the anaphase stage is due to some structural and/or numerical chromosomal aberrations in the cells uring mitosis (Parveen and Shadab, 2012). Binucleation is an ...
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Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning
... The micronucleus test in the buccal exfoliated cells was ...Wilcoxon test were used to compare the frequencies of alterations before and after X-ray ...
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Rev. bras. geriatr. gerontol. vol.19 número4
... The effects of aging, gender and lifestyle factors on inducing chromosomal damage (micronuclei) and nuclear degenerative changes were assessed using the micronucleus test on exfoliated cells of the oral ...
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Avaliação dos efeitos citogenotóxicos da diamina cadaverina, presente no necrochorume, por meio de ensaios com sistemas testes in vitro e in vivo
... KURAS, M.; NOWAKOWSKA, J.; SLIWIŃSKA, E.; PILARSKI, R.; ILASZ, R.; TYKARSKA, T.; ZOBEL, A.; GULEWICZ, K. Changes in chromosome structure, mitotic activity and nuclear DNA content from cells of Allium Test induced ...
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Test automation framework
... will test the overall software system or a specific module (or functionality) of the same ...to test a software sytem that is not fully ...of test cases that should cover (all) the software ...
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