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Reactive oxygen species (ROS)

Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis.

Alpha-synuclein induces lysosomal rupture and cathepsin dependent reactive oxygen species following endocytosis.

... a-synuclein dysregulation is a critical aspect of Parkinson’s disease pathology. Recent studies have observed that a- synuclein aggregates are cytotoxic to cells in culture and that this toxicity can be spread between ...

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Reactive oxygen species regulate protrusion efficiency by controlling actin dynamics.

Reactive oxygen species regulate protrusion efficiency by controlling actin dynamics.

... Productive protrusions allowing motile cells to sense and migrate toward a chemotactic gradient of reactive oxygen species (ROS) require a tight control of the actin cytoskeleton. However, the ...

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Testosterone improves erectile function through inhibition of reactive oxygen species generation in castrated rats

Testosterone improves erectile function through inhibition of reactive oxygen species generation in castrated rats

... Endothelial cells produce and release nitric oxide (NO), which induces the activation of soluble guanylyl cyclase and the accumulation of cyclic guanosine monophosphate (cGMP), resulting in the relaxation of smooth ...

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Diazoxide prevents reactive oxygen species and mitochondrial damage, leading to antihypertrophic effects

Diazoxide prevents reactive oxygen species and mitochondrial damage, leading to antihypertrophic effects

... imbalance in cardiac hypertrophy and heart failure [4e13]. What- ever the mechanism for increased oxidative imbalance, finding new tools to prevent it would be desirable. The first evidence for the role of oxidative ...

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The role of reactive oxygen species in Anopheles aquasalis response to Plasmodium vivax infection.

The role of reactive oxygen species in Anopheles aquasalis response to Plasmodium vivax infection.

... Malaria affects millions of people worldwide and hundreds of thousands of people each year in Brazil. The mosquito Anopheles aquasalis is an important vector of Plasmodium vivax, the main human malaria parasite in the ...

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The Association between Physical Exercise and Reactive Oxygen Species (ROS) Production

The Association between Physical Exercise and Reactive Oxygen Species (ROS) Production

... of oxygen. This rise in oxygen consumption combined with the activation of specific metabolic pathways during or after exercise results in the generation of Reactive Oxygen Species ...

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Macrophage migration inhibitory factor induces autophagy via reactive oxygen species generation.

Macrophage migration inhibitory factor induces autophagy via reactive oxygen species generation.

... induced reactive oxygen species (ROS) production and autophagy formation, including LC3-II expression, LC3 punctae formation, autophagic flux, and mitochondria membrane potential ...

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Reactive oxygen species and angiotensin II signaling in vascular cells - implications in cardiovascular disease

Reactive oxygen species and angiotensin II signaling in vascular cells - implications in cardiovascular disease

... Diseases such as hypertension, atherosclerosis, hyperlipidemia, and diabetes are associated with vascular functional and structural changes including endothelial dysfunction, altered contractility and vascular ...

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Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity

Involvement of glutamate and reactive oxygen species in methylmercury neurotoxicity

... This review addresses the mechanisms of methylmercury (MeHg)- induced neurotoxicity, specifically examining the role of oxidative stress in mediating neuronal damage. A number of critical findings point to a central role ...

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Reactive oxygen species in unstimulated hemocytes of the pacific oyster Crassostrea gigas: a mitochondrial involvement.

Reactive oxygen species in unstimulated hemocytes of the pacific oyster Crassostrea gigas: a mitochondrial involvement.

... The Pacific oyster Crassostrea gigas is a sessile bivalve mollusc whose homeostasis relies, at least partially, upon cells circulating in hemolymph and referred to as hemocytes. Oyster’s hemocytes have been reported to ...

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Does cotinine act upon reactive oxygen species and peroxidases?

Does cotinine act upon reactive oxygen species and peroxidases?

... Despite their physiological role in defence of the organism, reactive oxygen species have been implicated in initiating, accompanying or causing many diseases. There is some evidence that abnor- ...

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Production of reactive oxygen species in Dalbergia nigra seeds under thermal stress

Production of reactive oxygen species in Dalbergia nigra seeds under thermal stress

... KUO, M.C.; KAO, C.H. Aluminum effects on lipid peroxidation and antioxidative enzyme activities in rice leaves. Biologia Plantarum, v.46, p.149-152, 2003. http://download.springer.com/ ...

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Cytometry flow techniques for evaluation of reactive oxygen species produced by equine synovial cells fluid.

Cytometry flow techniques for evaluation of reactive oxygen species produced by equine synovial cells fluid.

... the reactive oxygen species (ROE) produced by distinct cell populations of the synovial fluid from rigid and inflamed joints in horses, and to identify an increase in the polymorphonuclear cells ...

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Reactive oxygen species, apoptosis and cancer

Reactive oxygen species, apoptosis and cancer

... very reactive HO · radical, which interacts with DNA causing the formation of mutagenic purines, pyri- midines and oxidative deoxyribose products, such as 8- hydroxy-2-deoxyguanosine (8OHdG) 6, 13 ...

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Aerobic Exercise Training Prevents the Onset of Endothelial Dysfunction via Increased Nitric Oxide Bioavailability and Reduced Reactive Oxygen Species in an Experimental Model of Menopause

Aerobic Exercise Training Prevents the Onset of Endothelial Dysfunction via Increased Nitric Oxide Bioavailability and Reduced Reactive Oxygen Species in an Experimental Model of Menopause

... of reactive oxygen spe- cies (ROS), prostanoid factors and a reduced nitric oxide (NO) bioavailability due to lower pro- duction and higher inactivation; these being the main triggers of endothelial ...

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J. Bras. Patol. Med. Lab.  vol.51 número4

J. Bras. Patol. Med. Lab. vol.51 número4

... of reactive oxygen species (ROS) plays an important role in the development of ...of reactive oxygen metabolites (d-ROMs) also stand out as acting in cardiovascular disease and ...

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TLR 2, TLR 4, ROS, óxido nítrico, P38 e IKK em células mononucleares de cães com leishmaniose Visceral tratadas com o imunomodulador P-MAPA: Larissa Martins Melo. -

TLR 2, TLR 4, ROS, óxido nítrico, P38 e IKK em células mononucleares de cães com leishmaniose Visceral tratadas com o imunomodulador P-MAPA: Larissa Martins Melo. -

... TLR4, reactive oxygen species (ROS), nitric oxide (NO) and p38 mitogen-activated protein kinase (p38MAPK) and IKK phosphorylation were studied in mononuclear cells from peripheral blood and ...

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Open Efeito da salinidade em células do sistema imune do ouriçodomar Echinometra lucunter

Open Efeito da salinidade em células do sistema imune do ouriçodomar Echinometra lucunter

... of reactive oxygen species (ROS), mitochondrial activity and ABC transporter activity were ...‰. Reactive oxygen species levels were higher when cells were incubated at 25 ‰ and ...

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Reference Values of Oxidative Stress Parameters in Adult Iranian Fat-Tailed Sheep

Reference Values of Oxidative Stress Parameters in Adult Iranian Fat-Tailed Sheep

... 2001). Reactive oxygen species (ROS) including superoxide radical, hydrogen peroxide and hydroxyl radical have a great impact on the normal function of biomolecules like nucleic acids, proteins and ...

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Avaliação do estado redox no sêmen humano e sua correlação com os parâmetros do ...

Avaliação do estado redox no sêmen humano e sua correlação com os parâmetros do ...

... Reactive oxygen species (ROS) at low levels are required for normal function of sperm, which are involved in fertilization capacity. However, evidences show that the excessive production of ROS leads ...

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