Retinoic acid (RA)
Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model of Parkinson's disease
... 1.4 Retinoic acid synthesis and ...of retinoic acid (RA) ...a retinoic acid response element (RARE) regulates transcription of RA target ...
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Retinoic acid activates two pathways required for meiosis in mice.
... mice, retinoic acid (RA), a vitamin A derivative, induces expres- sion of the gene Stra8, which in turn is required for the first critical steps of ...
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Retinoic acid protects from experimental cerebral infarction by upregulating GAP-43 expression
... or retinoic acid (150 mg RA/kg body weight) (12,13) were intraperitoneally injected in the latter two groups, and after the distal MCAO was performed, intraperitoneal injections were administered daily ...
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The Expression of Bone Morphogenetic Protein 2 and Matrix Metalloproteinase 2 through Retinoic Acid Receptor Beta Induced by All-Trans Retinoic Acid in Cultured ARPE-19 Cells.
... that retinoic acid (RA) can be synthesized and secreted by the retina and choroid and function as a biochemical signal [5], that plays an important role in the development and progression of axial myopia ...
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Cardiac remodeling induced by 13-cis retinoic acid treatment in acne patients
... Retinoic acid (RA) is the bioactive metabolite of vitamin A. It acts through nuclear retinoid receptors (RAR and RXR), alters protein synthesis in the heart and regulates embryonic development, tissue ...
4
Retinoic Acid Specifically Enhances Embryonic Stem Cell Metastate Marked by Zscan4.
... In the current study, we investigated how differentiation stimuli such as Dimethylsulfoxide (DMSO), Lif removal, and Retinoic Acid (RA) could affect Zscan4 metastate balance. Interest- ingly, we found that ...
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EXPRESSION OF SEC61 α IN F9 AND P19 TERATOCARCINOMA CELLS AFTER RETINOIC ACID TREATMENT
... Retinoic acid (RA) is a natural acidic derivative of vitamin A (retinol), which can affect proliferation and differentiation of a variety of cell types, and pattern formation during development (Strickland ...
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Dehydroepiandroesteron Accompanied Retinoic Acid Enhances Differentiation of P19 Embryonal Stem Cells into Neural Cells
... Objective: Dehydroepiandroesteron (DHEA) is a neurosteroid with potential effect on neu- rogenesis, neuronal survival and proliferation of neural progenitor cells. However there is no direct evidence for its biological ...
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Retinoic acid signaling plays a restrictive role in zebrafish primitive myelopoiesis.
... Retinoic acid (RA) is known to regulate definitive myelopoiesis but its role in vertebrate primitive myelopoiesis remains unclear. Here we report that zebrafish primitive myelopoiesis is restricted by RA in ...
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Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation.
... all-trans retinoic acid (RA) in pluripotent stem cells is accompanied by increased levels of aneuploidy, as previously described for cortical NPCs in ...
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Retinoic acid and cAMP inhibit rat hepatocellular carcinoma cell proliferation and enhance cell differentiation
... approaches. Retinoic acid (RA) is a natural derivative of vitamin A that regulates important biological processes including cell proliferation and ...
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Study of the retinoic acid regulated genes in the rodent hypothalamus controlling growth and appetite and the potential for the epigenetic control
... of retinoic acid in repressing inflammatory responses (Dheen et ...of retinoic acid whereas RALDH1 and RALDH2 catalyse the conversion of retinal into retinoic ...
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Retinoic acid signalling is activated in the postischemic heart and may influence remodelling.
... To our knowledge, no previous studies have reported activation of retinoic acid signalling in the heart in conjunction with myocardial ischemia and remodelling. It seems to be independent of ...
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Depletion of retinoic acid receptors initiates a novel positive feedback mechanism that promotes teratogenic increases in retinoic acid.
... Retinoic acid (RA) is the most active metabolic product of Vitamin A. Appropriate levels of RA are required for proper embryonic development and tissue maintenance in all vertebrates. Inappropriate levels ...
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Neofunctionalization in vertebrates: the example of retinoic acid receptors.
... known—all-trans retinoic acid (ATRA)—and genetic evidence in mice has suggested that retinoic acid (RA) metabolites do not play a significant developmental role ...amino acid positions ...
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Effect of all-trans retinoic acid on newly diagnosed acute promyelocytic leukemia patients: results of a Brazilian center
... for retinoic acid receptor alpha ...all-trans retinoic acid (ATRA), even though complete remission (CR) has not been sustained by ATRA therapy alone ...retinoid acid syndrome (RAS) and ...
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Sec61alpha synthesis is enhanced during translocation of nascent chains of collagen type IV in F9 teratocarcinoma cells after retinoic acid treatment
... In the present study, we tested the propo- sition that the translocation of secretory pro- teins through the ER membrane is the result of the enhanced production and utilization of Sec61a and may depend on the stage of ...
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Therapeutic application of retinoic acid-loaded nanoparticles for neurological and vascular repair in stroke
... of retinoic acid-loaded nanoparticles as the therapeutic ...agent. Retinoic acid regulates vascular function and can increase endogenous ...free retinoic acid: low solubility and ...
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A PU.1 suppressive target gene, metallothionein 1G, inhibits retinoic acid-induced NB4 cell differentiation.
... seeded at a density of 1610 5 cells/ml and treated with 1 m M all- trans retinoic acid (ATRA) or an equal volume of its solvent (ethanol). The cells were harvested after 72 h, or at specified times. For ...
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Normal HC11 and ras-transformed mouse mammary cells are resistant to the antiproliferative effects of retinoic acid
... after retinoic acid exposure suggests the presence of functional retinoic receptors, since one of the transcrip- tional targets of RAR ß is the RAR ß gene itself ...of retinoic acid is ...
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