sialic acid
Sialic acid changes in Dalton’s lymphoma-bearing mice after cyclophosphamide and cisplatin treatment
... that sialic acid could be used as a sensitive biomarker for lung cancer although their specificity is low ...in sialic acid con- centration with malignancy has not been reported because of ...
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Evaluation of Sialic Acid and Acute Phase Proteins (Haptoglobin and Serum Amyloid A) in Clinical and Subclinical Bovine Mastitis
... Haptoglobin and SAA increased significantly in both types of mastitis compared with control group (P<0.001). However, the ratio of HP/SAA was significantly different from the control group only in clinical mastitis. ...
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BIOTRANSFORMATION USING RECOMBINANT CMP SIALIC ACID SYNTHETASE AND α-2, 6-SIALYLTRAN SFERASE: ENZYMATIC SYNTHESIS OF SIALOSIDES
... The use of purified enzymes has been described for the synthesis of several sialosides using either a ‘one- pot’ system consisting of two enzymes or two/three-step processes where the biotransformations are carried out ...
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Effect of sialic acid loss on dendritic cell maturation
... of sialic acid restored spe- cific immune responses to mice non-responder DCs, leading to the proposal that reduction of sialic acid con- tributed to DC ...
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Treatment response in Kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G.
... and acid was removed by co-evaporation using 1:1 isopropanol: water (v/v) mixture under dry nitrogen flush followed by removal of the acid using a dry nitrogen ...The acid was removed completely by ...
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TRYPANOSOMA-CRUZI TRANS-SIALIDASE and NEURAMINIDASE ACTIVITIES CAN BE MEDIATED BY the SAME ENZYMES
... In addition, the neuraminidase substrate MuNana is a sialic acid donor for the trans-sialidase, and lactose decreases the amount of free sialic acid produced during the overa[r] ...
9
Pathology of Equine Influenza virus (H3N8) in Murine Model.
... with sialic acid α-2,3-galactose which are predominantly located in the upper respiratory tract and to a lesser extent in the bronchial epithelium of equines [68] as compared to tracheal ciliated epithelial ...
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Progesterone receptor-mediated regulation of N-acetylneuraminate pyruvate lyase (NPL) in mouse uterine luminal epithelium and nonessential role of NPL in uterine function.
... of sialic acid metabolism and transport could have adverse ...for sialic acid synthesis in the cytosol, leads to early postnatal lethality ...free sialic acid from lysosome to ...
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Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence.
... Although the NDV Ulster HN structure is overall very similar to the NDV AV [9] and Kansas HN structures [26,29], one variable active site loop, the D198 loop comprising R197-S200, shows significant structural differences ...
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Rev. Assoc. Med. Bras. vol.63 número4
... Table 1 and Table 2 show the results for salivary fluoride, sIgA, sIgG and sialic acid levels in the children of both groups. No statistically significant difference was found in salivary fluoride levels ...
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Hepatic inflammatory biomarkers and its link with obesity and chronic diseases
... Results: The sialic acid predicts the chance increase to become type2 diabetic independently of BMI. Moreover, the α 1 -antitripsin, ceruloplasmin, fibrinogen and hapto- globulin biomarkers, seem predict ...
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Human H3N2 Influenza Viruses Isolated from 1968 To 2012 Show Varying Preference for Receptor Substructures with No Apparent Consequences for Disease or Spread.
... One obvious concern was whether the Alexa labeling would interfere with binding. Alexa succinimidyl ester reacts with epsilon amino groups of lysine residues and could cause steric blocking or interfere with ionic ...
11
Probing the acceptor substrate binding site of Trypanosoma cruzi trans-sialidase with systematically modified substrates and glycoside libraries
... With octyl glycosides, TcTS inhibition is more pronounced than with the methyl glycosides and reducing sugars (38% activity remaining for octyl galactoside vs. 62% remaining for reducing galactose, for instance)(Fig. 7). ...
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Molecular characterization of the fibrinogen-erythrocyte interaction and its influence on cardiovascular pathologies by AFM-based force spectroscopy
... of sialic acid in their membrane, this leads to a decrease in erythrocyte-fibrinogen receptor binding events (without significantly affecting the forces of each single binding) and consequently to a ...
82
UNIVERSIDADE NOVA DE LISBOA
... generate sialic acid content during the biosynthesis of glycoconjugates and restore it during the recycling of surface receptors ...its sialic acid content and it is inhibited by a ...
85
Expression and structural-functional alterations of α-1-acid glycoprotein at the pathological state
... Alterations of N-glycan branching and expression of sialic acid on amniotic fluid alpha-1-acid glycoprotein derived from second and third trimesters of normal and prolonged pregnancies /[r] ...
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Design, synthesis and the effect of 1,2,3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase
... zole sialic acid-based derivatives 9–12 and the sialylmimetic ...that sialic acid unit seems not to be a requisite for TcTS inhibition, considering that carboxylate group from threonine amino ...
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Rev. Assoc. Med. Bras. vol.56 número1
... free sialic acid, and peroxidase activity in three groups of schoolchildren (overweight, obese and control) 7 to 10 years of ...free sialic acid and proteins concentrations in the whole saliva ...
1
Analysis of the stimulated whole saliva in overweight and obese school children
... and 10 years of age, from Bragança Paulista - SP. Three groups were formed: overweight, obese and control. Body Mass Index and diet intake by the Food Register method were evaluated. The salivary pH, low rate, buffer ...
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