T-lymphocytes
Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.
... enhancing T cell susceptibility to FK866 is suggested by the fact that PARP inhibitors only partially protect activated T lymphocytes from ...activated T cells by the sirtuin inhibitor ...in ...
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Broad T-cell receptor repertoire in T-lymphocytes derived from human induced pluripotent stem cells.
... antigen-specific T lymphocytes derived from hiPSCs have been reported. However, T lymphocyte populations with broad T cell receptor (TCR) diversity have not been ...producing T ...
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HLA-DR in Cytotoxic T lymphocytes predicts breast cancer patients' response to neoadjuvant chemotherapy
... of T lymphocytes, B lymphocytes, NK cells (Figure 1A), neutrophils, dendritic cells, M1 and M2 macrophages (Figure 1B) infiltrating the tumor, were similar between the two groups of ...of T ...
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Different subtypes of GABA-A receptors are expressed in human, mouse and rat T lymphocytes.
... taxis [7,8,11,13,18,19,20]. As the functional and pharmacological properties are dictated by the pentameric subunit-composition of the GABA-A channel complex, it is important to know the subtypes in the cells when ...
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Down-regulation of the interferon signaling pathway in T lymphocytes from patients with metastatic melanoma.
... CD8 T lymphocytes specific for tumor-associated antigens (TAAs) are often present in the blood of cancer patients and accumulate in tumor-draining lymph nodes and in primary and metastatic tumor sites ...CD8 ...
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ESTABLISHING THE REFERENCE RANGE FOR T LYMPHOCYTES SUBPOPULATIONS IN ADULTS AND CHILDREN FROM BRAZIL
... for T-lymphocytes subsets are based on data originated in other ...all T-cells subsets, were detected in blood donors from southeast / south regions while those living in the northern region had the ...
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T lymphocytes and macrophages in the intestinal tissues of dogs infected with Leishmania infantum
... CD8 T cells, similar to CD4 T cells, are classified into two subsets of cytolytic effector cells with distinct cytokine patterns, termed cytotoxic T lymphocytes 1 (Tc1) and cytotoxic T ...
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Immunomodulatory activity of Tityus serrulatus scorpion venom on human T lymphocytes
... Cell stimulation by pathogens in infectious and inflam- matory processes and by mitogens induces the expres- sion of activation markers in T, B, and NK cells. PHA, a commonly used mitogen, is a plant lectin that ...
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Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes.
... cytotoxic T-lymphocytes ...on T-cell effector ...viable T-cells induced by all three HDACis ii) the selective death of activated T-cells occurring at later time-points following ...
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Apoptosis in T lymphocytes from spleen tissue and peripheral blood of L. (L.) chagasi naturally infected dogs
... in T cells from the spleen and PBMC of infected dogs appear to be a phys- iological response to persistent immune activation; the mechanisms involved have yet to be ...of T cells probably reflects the low ...
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Reference Range for T Lymphocytes Populations in Blood Donors from Two Different Regions in Brazil
... of T-lymphocyte cells count in two different Brazilian ...the T-lymphocytes subpopulations (CD3+, CD4+, CD8+) in blood donors of two Brazilian cities, located in North (Belem, capital state of Para, ...
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Immunohistochemical expression of B and T-lymphocytes and TGF- βββββ in experimentally transplanted canine venereal tumor
... CD3 T- lymphocytes (MIZUNO et ...CD8 T-lymphocytes (GONZALEZ et al., 2000), B-lymphocytes, macrophages and the major histocompatibility complex (YANG et ...
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Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling.
... T lymphocytes play a critical role in cell-mediated immune ...alter T cell metabolism in order to meet the energetic and biosynthetic needs of a proliferating, active cell, but control of these ...
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Characterization of human γδ T lymphocytes infiltrating primary malignant melanomas.
... CD8 T cells within TILs have been extensively studied [20–21], very little is known about cd T ...cd T lymphocytes are important effector cells of the immune system that may play a role in the ...
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Cellular and matrix interactions during the development of T lymphocytes
... of T cell development, although there are extrathymic pathways especially in the gastrointestinal ...thymus, T cells are derived from blood-borne stem cells which migrate from sites of haemopoiesis into the ...
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Age-related changes of the multidrug resistance P-glycoprotein function in normal human peripheral blood T lymphocytes
... in T cells was highest in older individu- ...in T cells, P-gp functional expression is highest in cord blood and is progressively reduced with ...in T cell function with ...of T cell function ...
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Distribution of naive and memory/effector CD4+ T lymphocytes and expression of CD38 on CD8+ T lymphocytes in AIDS patients with tuberculosis
... T cell counts was an inclusion criterion for HIV patients (less than 350 cells/ µ L). This criterion, along with a lack of an ongoing opportunistic infection and antiretroviral therapy, was designed to enroll ...
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Actin cytoskeleton carbonylation in Human T-lymphocytes: a role in cellular senescence.
... concept gained strength along time. In fact, following the proteasome functional decrement, such degradation by autophagocytosis has been shown in primary cells [70] and cell lines ([55], [71], [72]) including, now, a ...
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HIV Infection in T-lymphocytes and Drug Induced CTL Response of a Time Delayed Model
... We have considered a basic mathematical model to rep- resent the virus dynamics of a HIV-1 infected individual including its response to RTI therapies. The RTI drugs actually impair the HIV-1 infected cells by inhibiting ...
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Combinatorial guidance by CCR7 ligands for T lymphocytes migration in co-existing chemokine fields.
... The differential ability of CCL19 and CCL21 for desensitiz- ing CCR7 has been demonstrated previously [24]. In addition, the physiological concentrations of CCL19 and CCL21 in LNs were approximated according to previous ...
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