tumour necrosis factor
Carta: pathogenesis of tumour necrosis factor-alpha antagonists-induced psoriasiform lesions
... As described by the authors , the pathogenesis of the tumour necrosis factor-alpha antagonists (anti-TNF-a)- induced psoriasiform lesions has not yet been fully clari- fied. 2 The most widely accepted ...
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Correlation of transforming growth factor-β1 and tumour necrosis factor levels with left ventricular function in Chagas disease
... Tumour necrosis factor (TNF) is a proinflammatory cytokine with increased expression in HF and may play a key role in the immunological imbalance governing Chagas disease progression to the cardiac ...
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Severity of chronic experimental Chagas’ heart disease parallels tumour necrosis factor and nitric oxide levels in the serum: models of mild and severe disease
... Chagas disease (CD) is a neglected tropical disease caused by the protozoan haemoflagellate parasite Try- panosoma cruzi, which afflicts about eight million indi- viduals in Latin America (Rassi Jr et al. 2010). In most ...
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Serial measurement of the circulating levels of tumour necrosis factor and its soluble receptors 1 and 2 for monitoring leprosy patients during multidrug treatment
... of tumour necrosis factor (TNF)-α and its soluble receptors (sTNF-R1 and sTNF-R2) in leprosy patients at different stages of multidrug treatment (MDT) in comparison with non-infected individuals and ...
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Tocilizumab and rituximab have similar effectiveness and are both superior to a second tumour necrosis factor inhibitor (TNFi) in rheumatoid arthritis patients who discontinued a first TNFi
... 24. Finckh A, Ciurea A, Brulhart L, Kyburz D, Möller B, Dehler S, et al. B cell depletion may be more effective than switching to an alternative anti-tumor necrosis factor agent in rheumatoid arthritis ...
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Tumour necrosis factor -308 and -238 promoter polymorphisms are predictors of a null virological response in the treatment of Brazilian hepatitis C patients
... mour necrosis factor (TNF) (-308 G/A, rs1800629 and -238 G/A, rs361525) genes and the outcome of PEGylated α-interferon plus ribavirin therapy were ...
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Cytoskeletal rearrangements in synovial fibroblasts as a novel pathophysiological determinant of modeled rheumatoid arthritis.
... well-recognized tumour necrosis factor-driven animal model of this disease and performed high-throughput expression profiling with subtractive cDNA libraries and oligonucleotide microarray ...
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Rev. Bras. Reumatol. vol.54 número5
... of tumour necrosis factor (anti-TNF) have been successfully used in sev- eral chronic inflammatory diseases such as Rheumatoid Arthritis (RA), but some studies have observed the development of ...
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Aparecimento de psoríase durante o tratamento das doenças inflamatórias intestinais com infliximabe: A terapia biológica deve ser suspensa?
... 10. Cullen G, Kroshinsky D, Cheifetz AS, Korzenik JR. Psoriasis associated with anti- tumour necrosis factor therapy in inflammatory bowel disease: a new series and a review of 120 cases from the ...
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Matrix metalloproteinase 7 is a candidate biomarker in systemic sclerosis-associated interstitial lung disease
... Results: A total of 25 DEGs were filtered. The GO anal- ysis revealed genes that were mainly enriched in im- mune response, chemokine activity, and extracellular regions. KEGG pathway analysis of the DEGs revealed that ...
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Alterations in cytokines and haematological parameters during the acute and convalescent phases of Plasmodium falciparum and Plasmodium vivax infections
... interferon-γ, tumour necrosis factor (TNF)-α, macrophage inflammatory protein-1β and granulocyte-colony stimulating factor levels than controls and maintained high levels during the ...
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Rev. Assoc. Med. Bras. vol.61 número6
... inhibitory factor OR receptors, tumor necrosis factor, member 11b OR tumor necrosis factor receptor superfamily, member 11b OR FDCR-1 protein OR FDCR 1 protein OR OCIF protein OR ...
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Erythropoietin reduces the expression of myostatin in mdx dystrophic mice
... Erythropoietin (EPO) has been well characterized as a renal glycoprotein hormone regulating red blood cell production by inhibiting apoptosis of erythrocyte progenitors in hematopoietic tissues. EPO exerts regulatory ...
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Citocinas e proteínas de fase aguda do soro como marcadores de regressão da resposta inflamatória ao tratamento da tuberculose pulmonar
... tumor necrosis factor-alpha (TNF-α), interleukine-10 (IL-10) and transforming growth factor-beta (TGF-β) were determined using ELISA in the supernatant of peripheral blood mononuclear cell and ...
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Clinics vol.63 número3
... INTRODUCTION: The production of TNF-α following LPS stimulation is one of the key steps in bacterial sepsis and inlamma- tion. The mechanism by which phosphodiesterase inhibition alters TNF-α production in the presence ...
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Clinics vol.69 número12
... The results of this work demonstrated that SOD2 levels were significantly increased in TPE patients. Due to their role in cellular metabolism, mitochondria are the major sites of ROS production. SOD2 is the only known ...
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Role of nuclear factor kappa B and reactive oxygen species in the tumor necrosis factor- α
... Figure 3. Tumor necrosis factor- α (TNF-α) decreased the ex- pression of E-cadherin in a nu- clear factor kappa B (NFκB)-de- pendent way. MCF-7 cells were pretreated with aspirin, N-acetyl cysteine ...
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Arq. Bras. Cardiol. vol.87 número1 en a05v87n1
... Figure 1 shows that median CRP levels were signifi - cantly higher in ACS patients, compared to control subjects, both on admission and at discharge, but not at three and six months. Median IL-6 levels declined ...
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Necroptosis occurs in osteoblasts during tumor necrosis factor- a stimulation and caspase-8 inhibition
... Some of our results are unclear and require further study. For example, the changes in RIPK3, MLKL, and caspase 3 mRNA levels were not consistent with the Figure 6. RT-PCR was conducted to measure mRNA levels of receptor ...
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Correlation Between Serum Tumor Necrosis Factor Alpha Levels and Clinical Severity of Tuberculosis
... On the other hand, in three patients the serum TNF alpha was undetectable: patient 9 (pulmonary with cavitations TB), patient 12 (pulmonary TB), and patient 21 (miliary TB). Patient 21 had a negative PPD skin test. We ...
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