Vitamin D receptor
Vitamin D receptor alleles and bone mineral density in a normal premenopausal Brazilian female population
... Figure 1 - Allele effect of the vitamin D receptor (VDR) geno- type on lumbar spine (A) and femoral neck (B) bone mineral density (BMD) in premeno- pausal Brazilian women. Data are reported as mean ± ...
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Fractures of the proximal femur: correlation with vitamin D receptor gene polymorphism
... Fractures are the feared consequences of osteoporosis and fractures of the proximal femur (FPF) are those that involve the highest morbidity and mortality. Thus far, evaluation of bone mineral density (BMD) is the best ...
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Differential regulation of vitamin D receptor expression in distinct leukemic cell lines upon phorbol ester-induced growth arrest
... between vitamin D receptor (VDR) abundance and cell proliferation rate has been shown in NIH-3T3 fibroblasts, MCF- 7 breast cancer and in HL-60 myeloblastic ...
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Osteoblast-specific transcription factor Osterix increases vitamin D receptor gene expression in osteoblasts.
... The vitamin D receptor (VDR) is a member of the nuclear hormone receptor superfamily that regulates target gene transcription to ensure appropriate control of calcium homeostasis and bone ...
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Vitamin D prevents hypoxia/reoxygenation-induced blood-brain barrier disruption via vitamin D receptor-mediated NF-kB signaling pathways.
... blood-brain barrier (BBB) disruption. Following hypoxic injury, an increase in intracellular reactive oxygen species (ROS) causes mitochondrial dysfunction, which further leads to intracellular oxidative stress (1). As a ...
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Vitamin D receptor (VDR) gene polymorphisms and genetic susceptibility to thyroid cancer
... the vitamin D receptor gene (VDR), located on chromosome 12q12-q14, and includes eight protein coding exons (exons 2-9) and one untranslated exon (exons ...
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Association of vitamin D receptor BsmI gene polymorphism with risk of tuberculosis: a meta-analysis of 15 studies.
... According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), a systematic literature searching was performed on PubMed, EMBASE and Chinese National Knowledge Infrastructure (CNKI) up to ...
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Vitamin D Receptor and Calcium-Sensing Receptor Gene Polymorphisms in Hypercalciuric Stone-Forming Patients
... Background/Aim: Some studies have identified an associa- tion of kidney stone formation with vitamin D receptor (VDR) or calcium-sensing receptor (CaSR) polymorphisms. We aimed to evaluate ...
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Population analysis of vitamin D receptor polymorphisms and the role of genetic ancestry in an admixed population
... The vitamin D receptor (VDR) is an essential protein related to bone metabolism. Some VDR alleles are differentially distributed among ethnic populations and display variable patterns of linkage ...
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Cdx2 polymorphism affects the activities of vitamin D receptor in human breast cancer cell lines and human breast carcinomas.
... Vitamin D plays a role in cancer development and acts through the vitamin D receptor ...the vitamin D pathway and different common single nucleotide polymorphisms have ...
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Functional significance of vitamin D receptor FokI polymorphism in human breast cancer cells.
... that vitamin D analogs and parent agents suppress the cell proliferation of ER+ cells more effectively compared to ER- ...cells. Vitamin D analogs do not provide any significant cell ...
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Vitamin D receptor gene mutations anD Vitamin D serum leVels in asthmatic chilDren
... Methods: A cross sectional study of 77 children aged 7 to 14 years old, who were attended at a specialized clinic. The children were divided into 3 groups: asthmatics who had been using inhaled corticosteroids (ICS) for ...
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Effect of Vitamin D Receptor Activators on Glomerular Filtration Rate: A Meta-Analysis and Systematic Review.
... Concerns about the possible acceleration of kidney function decline have long limited the use of VDRAs. Previous meta-analysis and systematic reviews confirmed that active vitamin D analogs suppress ...
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Genetic polymorphisms in vitamin D receptor, vitamin D-binding protein, Toll-like receptor 2, nitric oxide synthase 2, and interferon- γ genes and its association with susceptibility to tuberculosis
... of vitamin D is 50 nM (or 20 ng/ ...strated vitamin D deficiency in all major geographic re- gions of Brazil that could result in up to a 6-fold decrease in presumable normal serum levels of ...
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Association between vitamin D receptor gene polymorphisms and breast cancer risk: a meta-analysis of 39 studies.
... No linkage disequilibrium was shown between the Fok1 polymorphism and Bsm1, Taq1 and Apa1 polymorphisms [51]. Therefore, Fok1 can be considered as an independent marker within the VDR gene. The effect of this SNP on ...
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A prospective study of plasma vitamin D metabolites, vitamin D receptor polymorphisms, and prostate cancer.
... is vitamin D, of which high levels are found in seafood and dairy products, but which can also be made naturally by the body—more specifically, by sunlight-exposed ...think vitamin D might ...
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Braz. oral res. vol.23 número2
... Abstract: The aim of this cross-sectional study was to examine the re- lationship between the composition of the subgingival microbiota and the vitamin D receptor (VDR) gene polymorphism in Brazilian ...
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Rev. bras. cineantropom. desempenho hum. vol.18 número1
... Abstract – he aim of the study was to compare BMD among physically independent elderly women with diferent physical-functional proiles and vitamin D receptor gene (VDR) polymorphisms, as well as to ...
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Beyond mineral metabolism, the bright immunomodulatory effect of vitamin D in renal disease
... of vitamin D and is formed by two hydroxylation steps: a hepatic 25-hydroxylation of vitamin D and a subsequent kidney 1 alpha-hydroxylation ...of vitamin D3, 1, 25-dihydroxyvitamin D3, ...
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Evidence-based non-skeletal actions of vitamin D
... Vitamin D receptor (VDR) is a phosphoprotein member of the nuclear receptor superfamily that functions as a ligand-dependent transcription ...min D responsive elements present in the ...
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