[PDF] Top 20 Centrosomes and cilia in human disease
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Centrosomes and cilia in human disease
... formation and elongation, hence coordinating this event with DNA replication. In G2, the daughter centriole reaches full elongation and maturation with the recruitment of several molecules that are ... See full document
16
Caveolin-1 influences vascular protease activity and is a potential stabilizing factor in human atherosclerotic disease.
... of human Caveolin-1 (residues 82–101) (Cavtratin) and scrambled version were prepared as previously reported [24;25] ...For in vitro experiments, final concentration of each peptide was achieved by ... See full document
13
Polarity in ciliate models: from cilia to cell architecture
... Hammersmith and Grimes, 1981 ), probably by mechanisms similar to those operating in the metazoans de novo ...assembly, and their orientation from the “anarchic field” is equivalent to the process of ... See full document
23
Contribuction of human iPSCs to the study of neuron development and disease modelling in vivo
... 1994). In DS, density of dendritic spines has been reported inconsistently. In some individuals, a decrease in spine density was observed while in others this was normal, which suggests that a ... See full document
117
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease.
... sortilin, and M6PR, we isolated human glomeruli by laser capture microdissection and evaluated if the receptors’ mRNAs could be identified by RT- ...PCR. In order to avoid contamination with ... See full document
11
The Human Whey-acidic-protein Four-Disulfide Core -domain (WFDC) cluster on 20q13 region: evolutionary history and role in human health and disease
... Specifically, in monoandrous primates like gorillas and gibbons, in which females mate with a single male, the ejaculate is gelatinous in texture and does not ...chimpanzees and ... See full document
228
Gene expression regulation by upstream open reading frames and human disease
... ORF in unstressed conditions [1,2], or trigger mRNA decay [3–5]. However, in response to cellular stress, the presence of uORFs can promote the increased expression of certain stress-related mRNAs ...the ... See full document
12
Molecular epidemiology of human oral Chagas disease outbreaks in Colombia.
... reported in Colombia [28,37]. In the samples collected, TcIa, TcIb and TcId were detected in the clones analyzed as mixed infections within ...super-infection and/or co-infection within ... See full document
7
Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease
... activation and cytokines produced by these cells may create an environment that will influence T-cell func- ...served in indeterminate patients, the question arises as to whether they were associated with ... See full document
11
ARTIGO_A new coronavirus associated with human respiratory disease in China
... AY274119) and a coronavirus associated with bats (bat SL-CoVZC45, GenBank accession number ...regions and open-reading frame (ORF) of WHCV were mapped on the basis of this sequence alignment and ORF ... See full document
20
Role of Insulin and Igf-1 in Energy Metabolism in Huntington’s Disease: Studies in Cortical and Striatalneurons from Yac128 Transgenic Mice and Human Lymphoblasts
... [Floyd and Hensley, 2002]. Duarte et al, in 2005, investigated the effect of insulin on viability of cortical neurons and antioxidant defense mechanisms, after the induction of oxidative stress by ... See full document
83
Mixed Methods Survey of Zoonotic Disease Awareness and Practice among Animal and Human Healthcare Providers in Moshi, Tanzania.
... animals and humans. In Tanzania, research has shown that several zoonoses, including brucellosis, leptospirosis, and Q fever, are common, but under-diagnosed, causes of human ...quantitative ... See full document
18
Anemia and high therapeutic doses of recombinant human erythropoietin in chronic kidney disease - a linkage of risk?
... 41] and the use of animal models have been helpful to elucidate the underlying ...increase in myofibroblasts, responsible for collagen synthesis, leads to excessive ECM ...cells), and bone marrow ... See full document
238
Quantifying Creatinine And Urea In Human Urine Through Raman Spectroscopy Aiming At Diagnosis Of Kidney Disease
... read and signed the Consent Terms and answered a questionnaire on lifestyle habits and presence of previous disease and pathologies in close ...collected in sterile vials ... See full document
8
Single-cell transcriptomics in unravelling the molecular complexity of immunity in human disease
... improvements and massively parallel sequencing platforms boosted an increase in the number of cells studied in these analyses, ranging from only a few cells to hundreds of thousands of single cells ... See full document
96
Active Transmission of Human Chagas Disease in Colima Mexico
... study. In total, 405 blood samples were collected in the 218 homes sur- veyed, of which 10 resulted positive to IHA; 4 of them at titers higher than 1:16 and 6 with dilutions ...(2 in Colima- ... See full document
6
Development of an analysis pipeline for human microelectrode recordings in Parkinson’s disease
... step in this pre-processing part, since it can smooth out high-frequency fluctuations and/or remove periodic trends of a specific frequency from ...300 and 5000 ...(Butterworth and Chebyshev ... See full document
90
Impact of tRNA modifications and tRNA-modifying enzymes on proteostasis and human disease
... 5 and ncm 5 modifications are catalyzed by the Elongator complex [ 13 ], which is also engaged in transcriptional elongation and histone acetylation [ 43 ...]. In yeast, this complex catalyzes ... See full document
18
Common variation in ISL1 confers genetic susceptibility for human congenital heart disease.
... cases and controls were recruited from the Children’s Hospital of Philadelphia (CHOP) between 12/12/2003 and 08/25/2008 on a protocol approved by the Institutional Review Boards of CHOP and the ... See full document
7
Cilia distal domain: diversity in evolutionarily conserved structures
... KIF7 and Gli proteins to the tips of cilia, and the activation of the transcriptional activity of Hh target genes ...(PPFIA1) and phosphatase PP2A promotes KIF7 dephosphorylation and ... See full document
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