[PDF] Top 20 CHART 1 Pathogenic mechanisms mediated by

... LA is the most specific test for the diagnosis of APS and should be performed according to the International Soci- ety for Thrombosis and Hemostasis. These are functional investigations and comprise three stages. The ... See full document

... conducted by combining whole cell protein extracts with SDS-PAGE loading buffer in a 1:1 (v/v) ratio, incubation at 100uC for 3 min, followed by loading into precast 10% polyacrylamide gels ... See full document

... Meiotic crossovers (COs) generate genetic diversity and are critical for the correct comple- tion of meiosis in most species. Their occurrence is tightly constrained but the mechanisms underlying this limitation ... See full document

... produced by mutations in either of two tumor suppressor genes, TSC1 and TSC2 ; it is characterized by hamartomatous tumors, and is associated with severe neurological and behavioral ...produced by ... See full document

... Aedes aegypti (Linnaeus, 1762) is the most important vector of dengue, chikungunya and Zika viruses. Originally from Africa, this mosquito species invaded other territories and currently has a worldwide tropical ... See full document

... induced by a variety of stimuli, including S. typhimurium infec- tion, HMGB-1 did not undergo caspase-1-mediated processing before its secretion, but extracellular HMGB-1 was ... See full document

... encoded by viral alternative reading frames (ARF). We studied here the mechanisms of HIV-1 escape from CTLs targeting one such cryptic epitope, Q9VF, encoded by an HIVgag ARF and presented ... See full document

... Caused by the basidiomycete yeast Crypto- coccus neoformans, cryptococcosis globally results in approximately 215,000 infections per year, leading to 180,000 deaths patients (Rajasingham et ...directed by ... See full document

... monomer by isopeptide bonds forming a K48-G76- linked poly-ubiquitination ...63 by K63-G76 bonds, the destination could be probably non-proteolytic, like clearance by autophagy (Tan et ...is ... See full document

... be mediated by NK-1 receptors (6,8,12,13). NK-1 receptor antagonists may be effective in the treatment of depression in patients with symptoms of anxiety, leading to research efforts aimed at ... See full document

... Due to growing popularity, RNA-interference has be- come widely used in innumerous cases of gene silencing. Through induction by plasmids or virus vectors, RNAi has broadened its range of application (Bartel, ... See full document

... A single diagnostic system cannot possess all the desired characteristics. Therefore hybrid systems were developed to integrate more than one diagnostic methodology, which can be quantitative, qualitative or ... See full document

... ponents by antifungal agents will lyse cells in the absence of an osmo-protectant, but cells will continue to growth if a suitable stabilizer is present in the ... See full document

... NFkB-dependent mechanisms that trigger cell survival, with the anti-apoptotic activities of TNF-a regarded to be its dominant ...is mediated by TNF receptor I (TNFR1) via the intermediate adapter TNF ... See full document

... triggered by hor- mones, neurotransmitters, or growth factors as a second messenger to trigger a variety of intracellular responses, including contraction, secretion, growth and ...to 1 µ M (where µ M ... See full document

... timewise by two characteristics: centralization - the process average and dispersion, estimated by its standard deviation or range of data (HO & QUININO, ...control chart is to seek for signs of ... See full document

... company, by monitoring for two consecutive years a group of three agricultural machinery for soil preparation operations in this ...operations by providing additional parameters to indices used for this ... See full document

... As for the equivalences, the specialists were instructed to as- sign the number +1 when they considered the Portuguese trans- lation to be equivalent in all its aspects (semantic, conceptual, idiomatic and ... See full document

... applied by the probe to induce withdrawal was ...Approximately 1 cm of the main trunk proximal to the trifuraction was isolated and 4 strands of 4-0 chromic gut were tied around the nerve , 1 mm ... See full document

... The concept of bacteria living within the context of a community rather than simply as autonomous entities is one that is quickly gaining acceptance. These communities of organisms living within extracellular matrix are ... See full document