[PDF] Top 20 Development of drug-loaded polymeric nanomicelles for stem cell osteogenic differentiation

Development of drug-loaded polymeric nanomicelles for stem cell osteogenic differentiation

... (OS) differentiation medium. (A) Dose regime of Dex and Naringin in this ...activity of hASCs over 21 days in OS-Dex, with different Naringin concentrations, expressed in nmol p-nitrophenol ... See full document

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Bioinstructive Naringin-Loaded Micelles for Guiding Stem Cell Osteodifferentiation

... delivery of Naringin to skeletal sites was only attempted by impregnation in implantable scaffolds, porous composites or in ...the development of bone graft materials either to enhance the repair ... See full document

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Development of three-dimensional umbilical cord-derived mesenchymal stem cell cultures for differentiation into hepatocyte-like cells : apotential breakthrough in toxicological drug screening

... to cell differentiation, since hMSC differentiation depends not only on cytokines and growth factors but also on mechanical gradients [307, 308, ...shape of the multicellular sheet surface ... See full document

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Development of a polymeric matrix based on hyaluronic acid and dextrin hydrogels for the expansion of undifferentiated mesenchymal stem cells

... region of the ...potential of different cell ...that of MSCs derived from bone ...expression of hematopoietic markers such as CD34 and CD45 ...unable of undergoing ... See full document

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In vitro germ cell differentiation from cynomolgus monkey embryonic stem cells.

... one of these markers. A combination of several germ cell markers will thus be necessary to detect germ cell differentiation from ES ...detection of germ cell ... See full document

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Sox9 potentiates BMP2-induced chondrogenic differentiation and inhibits BMP2-induced osteogenic differentiation.

... pression of Sox9 potentiates BMP2-induced chondrogenesis and inhibits BMP2-induced osteogenesis, it was imperative to demon- strate if overexpression of Sox9 play such a role in ...established stem ... See full document

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Recombinant proteins in differentiation of stem cells

... mL of ice cold STE Buffer (10 mM Tris-HCl, pH ...mM of DTT, 1 mM of PMSF and 1.5 mL of 10% Sarkosyl (final concentration 1,5%) were ...time of 1 min (On 7’’, Off 10’’ cycle; model ... See full document

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TGF-β1 on induced osteogenic differentiation of human dermal fibroblast

... both osteogenic groups had the same behavior with regard the expression curve during the experimental time, the OSTEOG/TGF-β1 group achieved signiicantly higher ALP and OC levels and showed no signiicant ... See full document

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Extensive neuronal differentiation of human neural stem cell grafts in adult rat spinal cord.

... points of differentiation in vitro (0, 14, 29, and 42 d after withdrawal of bFGF) using Trizol (Invitrogen ...lg of RNA with the iScript cDNA Synthesis kit (Bio-Rad ...glial cell ... See full document

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Development of human osteogenic cell sheets co-cultured with endothelial and pericyte-like cells

... presence of these cells around both capillaries (diameter < 10 µm) and arterioles (diameter from 10 to 100 µm) in all organs of human body, based on their ubiquitous expression of NG2 and CD146 ... See full document

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The osteogenic differentiation stimulating activity of Sea cucumber methanolic crude extraction on rat bone marrow mesenchymal stem cells

... dose of 12.5 and 25 µg/ml) and (in the presence of osteogenic medium) at a dose of ...presence of osteogenic medium and showed that ...have osteogenic ... See full document

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Development of VEGF-loaded PLGA matrices in association with mesenchymal stem cells for tissue engineering

... Evaluation of the hydrophilicity/hydrophobicity of the scaffolds is made by the measurement of the contact ...measurement of the contact angle is lower than 90° and hydrophobic when it is ... See full document

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Attapulgite-doped electrospun poly(lactic-co-glycolic acid) nanofibers enable enhanced osteogenic differentiation of human mesenchymal stem cells

... solvent of THF–DMF (v/v ¼ 3 : 1) under magnetic stirring overnight to obtain a homogeneous solution with a concentration of 25% ...potential of 20 kV, steel capillary was ... See full document

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Mechanomodulation of chondrogenic differentiation of msesenchymal stem cells

... cartilage stem/progenitor cells (CSPCs) population was identified on cartilage ...study of these cells will help to develop a more effective cell ...injection of autologous chondrocytes is an ... See full document

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Coaxial Electrospray of Curcumin-Loaded Microparticles for Sustained Drug Release.

... image of the stable coaxial cone-jet structure and a microscopic image of resultant droplets directly collected after the breakup of the coaxial ...part of solvent has evaporated. The mean ... See full document

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Transcriptomics comparison between porcine adipose and bone marrow mesenchymal stem cells during in vitro osteogenic and adipogenic differentiation.

... median of the background and GenePix flag ...total of 82 microarrays were adjusted for dye and array effect (Loess normalization and array centering), duplicated spot intensities were not averaged and were ... See full document

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Substrate stiffness and oxygen as regulators of stem cell differentiation during skeletal tissue regeneration: a mechanobiological model.

... regulators of mesenchymal stem cell (MSC) ...MSC differentiation by attempting to simulate regenerative events such as bone fracture repair, where repeatable spatial and temporal patterns ... See full document

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Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation.

... phenotype of human mesenchymal stem cells (hMSCs) and the localization and transcriptional activity of ...hydrogels, cell adhesion and morphology were visualized by light ...the cell ... See full document

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Carcinoembryonic antigen targeted polymeric nanoparticles for drug delivery

... one of the polymers most used to produce nanoparticles ...copolymer of polylactic acid (PLA) and polyglycolic acid (PGA) is biocompatible and biodegradable and approved by US FDA and EMA (European Medicines ... See full document

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Stem cell therapy of cataract

... Research has been conducted to find ways to treat cataract. Cell and tissue- based therapeutic procedures are new strategies for this purpose. O’Connor et al in 2007 showed that the lens epithelial pieces that ... See full document

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