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[PDF] Top 20 Directed evolution of model-driven spreadsheets

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Directed evolution of model-driven spreadsheets

Directed evolution of model-driven spreadsheets

... high-level model, based on object-oriented development, that allows describing spreadsheet business logic using concepts like classes and ...collection of objects containing a single data value, and named ... See full document

96

Directed evolution of a model primordial enzyme provides insights into the development of the genetic code.

Directed evolution of a model primordial enzyme provides insights into the development of the genetic code.

... all of the simplified CMs, the MD simulations revealed how local interactions that are perturbed in the simplified CMs were restored during directed ...environments of the residues that changed ... See full document

9

Molecular evolution of a peptide GPCR ligand driven by artificial neural networks.

Molecular evolution of a peptide GPCR ligand driven by artificial neural networks.

... demands of de novo drug design (small training sets, fast convergence, and few design ...blocks of a GNN model that was designed to cover possible interactions between distant amino ...topology ... See full document

11

Development of novel bacterial enzymes for medical diagnosis through directed evolution

Development of novel bacterial enzymes for medical diagnosis through directed evolution

... out of 15 residues) and additionally, contains three major conserved regions in this family: the FAD-binding domain, the attachment loop, and the substrate-binding ...(members of GMC family) and with three ... See full document

66

Kinematics and geometry of structures in the southern limb of the Paraíba do Sul divergent structural fan, SE Brazil: a true transtensional shear

Kinematics and geometry of structures in the southern limb of the Paraíba do Sul divergent structural fan, SE Brazil: a true transtensional shear

... folding of flat-lying thrust ...limb of the divergent fan suggest a two stage kinematic evolution in high-temperature condi- tions: an earlier stage with top-to-SSW/SW sinistral thrusting and ... See full document

17

In-frame amber stop codon replacement mutagenesis for the directed evolution of proteins containing non-canonical amino acids: identification of residues open to bio-orthogonal modification.

In-frame amber stop codon replacement mutagenesis for the directed evolution of proteins containing non-canonical amino acids: identification of residues open to bio-orthogonal modification.

... dimension of 6.4x6.1x7.8 nm. This was populated using the SPC water model to solvate the system to a total number of 16986 sol- vent ...steps of steepest de- scent method followed by 500 steps ... See full document

18

Querying for model-driven spreadsheetsd

Querying for model-driven spreadsheetsd

... Instead of writing the query using column names, one must use the column letters (as shown in Figure 8) to write his or her ...support evolution since they do not adapt/evolve when the spreadsheet data ... See full document

86

Evolution of model-driven spreadsheets

Evolution of model-driven spreadsheets

... over model, instance and auxiliary data structures, only the ones that provide the operations are needed to ...set of functions is defined, where each function from that set invokes a model operation ... See full document

74

Model-Driven Software Evolution: The Multiple Views

Model-Driven Software Evolution: The Multiple Views

... The evolution of a model-based system involves a team of stakeholders within the ...objective of the team differs from each ...characteristics of the evolving ...context ... See full document

6

Genetic diversity in the SIR model of pathogen evolution.

Genetic diversity in the SIR model of pathogen evolution.

... drift evolution is driven by continuous positive Darwinian selection [21], or by epochal selection ...Our model makes clear Figure 7. Pattern and level of genetic diversity in the coding ... See full document

8

Verification of the multi-layer SNOWPACK model with different water transport schemes

Verification of the multi-layer SNOWPACK model with different water transport schemes

... properties of the snowpack, for exam- ple with the purpose of avalanche ...presence of liquid water can reduce the strength of a snowpack considerably (Col- beck, 1982; Conway and Raymond, ... See full document

23

Modeling and verification of the nonlinear system of oscillation platform of continuous casting mold driven by servo motor

Modeling and verification of the nonlinear system of oscillation platform of continuous casting mold driven by servo motor

... receipt of the following financial sup- port for the research, authorship, and/or publication of this article: Item sponsored by the Natural Science Foundation of China and Baosteel Group ... See full document

9

Climate-driven ichthyoplankton drift model predicts growth of top predator young.

Climate-driven ichthyoplankton drift model predicts growth of top predator young.

... effect of AW inflow on the variability in the climatic conditions in the Barents ...much of the relative contribution of young cod from the different spawning grounds along the Norwegian coast to ... See full document

9

Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase.

Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase.

... The kinase assay was performed with a Beacon Tyrosine kinase assay kit (Invitrogen, A- 35725) according to the manufacturer’s instructions. The kinase buffer was prepared by sup- plementing the provided buffer with ... See full document

22

A model for the evolution of extremely fragmented macronuclei in ciliates.

A model for the evolution of extremely fragmented macronuclei in ciliates.

... absence of a regulatory mechanism to control copy number, multiple rounds of amitosis inevitably lead to the loss of chromosomes and consequent cell ...elimination of a chromosome, imbalances ... See full document

7

Sensitivity of the Amazon biome to high resolution climate change projections

Sensitivity of the Amazon biome to high resolution climate change projections

... Inland model at daily frequency. The months are chosen as representative of opposite precipitation regimes in the Amazon ...terms of the spatial ...part of the continent and over tropical ... See full document

14

FOSTERING E-PARTICIPATION SUSTAINABILITY THROUGH A BPM-DRIVEN SEMANTIC MODEL

FOSTERING E-PARTICIPATION SUSTAINABILITY THROUGH A BPM-DRIVEN SEMANTIC MODEL

... ways of organising public policies, service provision and development activities (Anttiroiko, ...analysis of e-Governance definitions found both in academic literature and prominent Organisations’ ... See full document

194

Anticyclonic atmospheric circulation as an analogue for the warm and dry mid-Holocene summer climate in central Scandinavia

Anticyclonic atmospheric circulation as an analogue for the warm and dry mid-Holocene summer climate in central Scandinavia

... fall of the temperature whereas the reconstructions show that major changes in summertime climate took place towards higher mid-summer tem- peratures and markedly dry climatic ... See full document

26

Derivation of RCM-driven potential evapotranspiration for hydrological climate change impact analysis in Great Britain: a comparison of methods and associated uncertainty in future projections

Derivation of RCM-driven potential evapotranspiration for hydrological climate change impact analysis in Great Britain: a comparison of methods and associated uncertainty in future projections

... generation of RCMs cannot always accurately reproduce some impor- tant climate variables, an issue well known for precipitation and temperature, so forms of bias correction have often been applied to RCM ... See full document

28

Using data-driven model-brain mappings to constrain formal models of cognition.

Using data-driven model-brain mappings to constrain formal models of cognition.

... modules of the ACT-R architecture operate in parallel, but each module itself proceeds serially ...the model, because performance on those tasks is dependent on differ- ent modules (aural and problem state ... See full document

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