[PDF] Top 20 FcgammaRIIb inhibits allergic lung inflammation in a murine model of allergic asthma.

... Allergic asthma is characterized by airway eosinophilia, increased mucin production and allergen-specific ...regulator of allergic diseases like anaphylaxis and allergic ...role ... See full document

... prevalence of inflammatory disease. Short- chain fatty acids (SCFAs), the major of fiber metabolites, have profound effects on T cells func- tion and differentiation, which has been demonstrated by mounting ... See full document

... chronic lung disease of which the mechan- ism is little ...role in the under- standing of the mechanism of ...index of the asthmatic mouse model is AHR and airway ... See full document

... released in allergic lung inflammation and that they participate in the physiopathology of ...LTs in innate immunity has recently emerged: Cys-LTs were shown to enhance ... See full document

... of asthma. Up to now, its quantification still requires invasive methods. In this study, we aimed at determining whether in vivo micro-computed tomography (micro-CT) is able to demonstrate ... See full document

... bronchial asthma, a clinical complication of persistent inflammation of the airway and subsequent airway hyper-responsiveness, is a leading cause of morbidity and mortality in ... See full document

... the asthma model, female BALB/c mice were challenged with ovalbumin (OVA), and then treated daily with farrerol (20 and 40 mg/kg, ip) as a therapeutic treatment from day 22 to day 26 post ...acute ... See full document

... involved in the induction of NO ...effect of systemic endotoxin (LPS) administration on established airway inflammation and AHR in a murine asthma ...model. ... See full document

... a model of allergen-induced lung inflammation, we applied fluorescence imaging in combination with near-infrared (NIR) fluorescently-labeled dendritic polyglycerol sulfates (dPGS), a ... See full document

... homing in this species. After allergen challenge, eotaxin gene expression in the lung is further increased and par- allels the peak changes in eotaxin protein that we have observed in ... See full document

... activity of pulmonary nerves, and suppress the activation of the inflamma- tory cells ...distensibility of the airways, exag- gerates narrowing of the airway lumen when smooth muscle shortens, ... See full document

... lungs of 10-wk-old mice with RBP-j–deficient skins were normal and did not show any sign of allergic inflammation under standard housing conditions; however, the longest-living mutant animals ... See full document

... levels in the nasal mucosa were substantially elevated in our mouse model of OVA-induced AR, suggesting that HIF-1a was ...administration of 2ME2. In addition, the increased VEGF ... See full document

... role of IL-33 in natural allergen-induced allergic lung inflammation, but our results also suggest that the vac- cine could be further evaluated for therapeutic ...purposes. In ... See full document

... severity of allergic asthma in wild type mice, as measured by significant decreases in infiltration of eosinophils and secretion of proinflammatory cytokines and ... See full document

... role of NO in inflammatory cell recruitment, no effects in eosinophil recruit- ment are still a matter of ...inhibitors of NO reduced allergen-induced eosinophilia (Feder et ... See full document

... observed in 6.3% of the patients, indicating that additional interventions are necessary in order to reduce the exacerbations and hospitaliza- tions due to asthma during the follow up ... See full document

... assessing asthma or rhinitis control were categorized as dichotomous variables, classifying the patient as controlled or ...out of a scale ranging from 0 (bad) to 10 (good), according to previous reports ... See full document

... AR: allergic rhinitis; ARIA: allergic rhinitis and its impact on asthma; CDSS: clinical decision support system; CRD: chronic respiratory disease; DG CONNECT: directorate general for communications ... See full document

... development of Th1 and Th2 cells has been shown to be primarily regulated by the expression of transcription ...role in inducing the expression of Th2 cytokines ...member of the T-box ... See full document