Top PDF Genome-wide search for strabismus susceptibility loci.

Genome-wide search for strabismus susceptibility loci.

Genome-wide search for strabismus susceptibility loci.

... The genome-wide search was performed with amplifi- cation by polymerase chain reaction (PCR) of 400 markers in microsatellite regions with∼10 cM ...

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An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.

An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits.

... out genome-wide association studies (GWAS) has led to the rapid progression of the field of complex- disease genetics over the past few ...stringent genome-wide significance threshold alone ...

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Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population.

Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population.

... Quanto version 1.2.4 was employed for sample size calculation using minor allele frequency data from dbSNP database (http://www.ncbi.nlm.nih.gov/projects/SNP/). The categorical data of SNPs for association analysis with ...

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A genome-wide association search for type 2 diabetes genes in African Americans.

A genome-wide association search for type 2 diabetes genes in African Americans.

... T2DM susceptibility should increase with meta-analysis of this GWAS data and other GWAS currently being conducted in African-American popula- ...ESRD loci which are distinct from those presented herein ...

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Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.

Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.

... In summary, we have identified the locus including the bromodomain-containing gene [21], BAZ2B, as a new SCD susceptibility locus. The bromodomain is an exclusive protein domain known to recognize acetyl-lysine ...

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HBV-related hepatocellular carcinoma susceptibility gene KIF1B is not associated with development of chronic hepatitis B.

HBV-related hepatocellular carcinoma susceptibility gene KIF1B is not associated with development of chronic hepatitis B.

... HLA loci, have been extensively investigated in the progression to CHB, but results were inclusive ...recent genome- wide association study (GWAS) by Kamatani et ...

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A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

A genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility loci.

... (rs8034191 and rs1051730, p = 0.029 and 0.023, respectively (http://www.b58cgene.sgul.ac.uk/, accessed [3/7/2008]). Histori- cally, nicotinic receptors are classified as neuronal or muscle-type, based on their initial ...

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Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.

Evaluation of candidate nephropathy susceptibility genes in a genome-wide association study of African American diabetic kidney disease.

... nephropathy loci in 965 African American (AA) cases with T2D-ESKD and 1029 AA population-based controls extending prior ...eight loci were significantly associated ...

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A novel statistic for genome-wide interaction analysis.

A novel statistic for genome-wide interaction analysis.

... entire genome and also raise several serious challenges for genome-wide interaction ...the genome will be extremely ...ensuring genome-wide significance level of ...to ...

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Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.

Amerind ancestry, socioeconomic status and the genetics of type 2 diabetes in a Colombian population.

... gene loci in susceptibility to T2D in a sample of 876 T2D cases and 399 controls from Antioquia ...T2D genome-wide association studies, consistent with a role for Old World variants in ...

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Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.

Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.

... According to publicly available expression data (http://genome. ucsc.edu), in humans, BC034767 is expressed in the testes only, while TOX3 expression has been shown in the salivary glands, the trachea, and in the ...

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Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease.

... In summary, we have for the first time used a rapid, web-based enrollment method to assemble a large population for a genome- wide association study of PD. We have replicated results from numerous previous ...

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Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort.

Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort.

... In general, when performing GWAS with quantitative mea- surements, the potential for type I errors can be high. However, Bonferroni is a very conservative correction and the association of a given genetic variant on ...

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Intronic L1 retrotransposons and nested genes cause transcriptional interference by inducing intron retention, exonization and cryptic polyadenylation.

Intronic L1 retrotransposons and nested genes cause transcriptional interference by inducing intron retention, exonization and cryptic polyadenylation.

... In ABCA minigene, the presence of cryptic acceptor splice site upstream to L1 59 UTR determined the efficiency of L1-induced TI, because its deletion increased intron retention about 5-fold. Therefore, the occurrence of ...

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Reconstructing Roma history from genome-wide data.

Reconstructing Roma history from genome-wide data.

... After this manuscript was submitted, two other studies characterizing the population history of Roma were published. First, a study based on Y-chromosome haplogroups showed that on the paternal lineage, Roma haplotypes ...

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Properties of local interactions and their potential value in complementing genome-wide association studies.

Properties of local interactions and their potential value in complementing genome-wide association studies.

... pair-wise genome scans using BiForce and conventional GWAS in all eight metabolic traits in both cohorts, identified and tested replication of genome-wide significant epistatic ...combined ...

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Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.

Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.

... whole genome sequences (WGS) for 50 individuals comprising 18 parent-child trios and 8 additional parent-child pairs from the extended pedigree (Figure ...whole genome sequencing that included a) the most ...

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Phenotypic Characterization and Genetic Dissection of Growth Period Traits in Soybean (Glycine max) Using Association Mapping.

Phenotypic Characterization and Genetic Dissection of Growth Period Traits in Soybean (Glycine max) Using Association Mapping.

... study, genome-wide association analysis (GWAS) was exploited to detect the quantitative trait loci (QTL) for num- ber of days to flowering (ETF), number of days from flowering to maturity (FTM), and ...

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Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis.

Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis.

... blood. Loci-specific differentially methylated and expressed genes in sALS spinal cord were identified by genome-wide 5mC and expression profiling using high- throughput ...

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Detecting Loci under Recent Positive Selection in Dairy and Beef Cattle by Combining Different Genome-Wide Scan Methods

Detecting Loci under Recent Positive Selection in Dairy and Beef Cattle by Combining Different Genome-Wide Scan Methods

... scanning genome-wide data for selection ...neutral loci may be the most difficult issue, as those variants were probably seldom typed in SNP arrays, and even with whole genome sequence data, ...

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