[PDF] Top 20 How cells initiate Epithelial-to-Mesenchymal Transition?
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How cells initiate Epithelial-to-Mesenchymal Transition?
... dedicated to the analysis of large networks, motivated by the emergence of large quantitative and qualitative data sets, generated from the always evolving experimental techniques in genomics and proteomics ... See full document
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Salinomycin enhances doxorubicin sensitivity through reversing the epithelial-mesenchymal transition of cholangiocarcinoma cells by regulating ARK5
... due to the development of drug resistance. Epithelial-mesenchymal transition (EMT) of cancer cells is widely accepted to be important for metastasis and progression, but it has ... See full document
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The role of the miR-200 family in the epithelial-to-mesenchymal transition (EMT)
... complementary to target miRNAs, are able to bind and prevent miRNAs from interacting with their targets, thereby upregulating their mRNA levels 36-37 ...addition to sequester miRNAs, antagomirs can ... See full document
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A novel network integrating a miRNA-203/SNAI1 feedback loop which regulates epithelial to mesenchymal transition.
... promotes epithelial-like properties in breast cancer cells Next, we investigated the role of miR-203 in relationship with SNAI1 expression in breast carcinoma ...MCF7-SNAI1 cells, ectopically ... See full document
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Long Non-Coding RNA MALAT1 Mediates Transforming Growth Factor Beta1-Induced Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells.
... tumor cells and promoting tumor metastasis ...contributes to EMT in fibrotic diseases, like ...RPE cells, a hallmark in the pathogenesis of ... See full document
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Gefitinib inhibits invasive phenotype and epithelial-mesenchymal transition in drug-resistant NSCLC cells with MET amplification.
... resistance to EGFR tyrosine kinase inhibitors ...resistant cells can proliferate and survive regardless of the presence of gefitinib, whereas the absence of the drug significantly enhanced cell migration ... See full document
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A novel network profiling analysis reveals system changes in epithelial-mesenchymal transition.
... NetworkProfiler to gene expression microarray data from 762 cancer cell lines to determine system changes related to the epithelial-mesenchymal transition ...The ... See full document
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Prolyl-4-hydroxylase 3 (PHD3) expression is downregulated during epithelial-to-mesenchymal transition.
... tied to tumorigenesis, as they regulate cell metabolism and angiogenesis through their control of hypoxia-inducible factor (HIF) ...aimed to investigate this role by closely examining the relationship ... See full document
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Col1A1 production and apoptotic resistance in TGF-β1-induced epithelial-to-mesenchymal transition-like phenotype of 603B cells.
... blast-like cells via EMT to promote liver fibrosis development is still under debate ...positive cells derived from cholangiocytes during murine liver fibrosis, suggesting that cholangiocytes might ... See full document
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Ginsenoside 20(S)-Rg3 targets HIF-1α to block hypoxia-induced epithelial-mesenchymal transition in ovarian cancer cells.
... Total RNA was extracted from cultured cells using RNAfast 200 (Fastagen Biotech Co. Ltd., Shanghai, China) according to the manufacturer’s instructions. RNA concentration and purity were determined on a UV ... See full document
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TWIST1 a new determinant of epithelial to mesenchymal transition in EGFR mutated lung adenocarcinoma.
... H1650 cells were treated during 4, 12, 24 and 48 hours with EGF at concentrations ranging from 5 to 120 ng/ ...All cells were therefore treated at 5 and 25 ng/ml during 24 and 48 hours in triplicate ... See full document
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1-Methyl-D-tryptophan potentiates TGF-β-induced epithelial-mesenchymal transition in T24 human bladder cancer cells.
... linked to indoleamine 2,3-dioxygenase ...believed to contribute to carcinoma development by modulating immunossupressive molecules, including ...the epithelial-mesenchymal transi- tion ... See full document
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Epigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer.
... luminal epithelial cells ...in cells with loss of Elf5 expression ...luminal epithelial cells, although mechanisms underlying these effects remain to be elucidated ...luminal ... See full document
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Upregulation of TrkB promotes epithelial-mesenchymal transition and anoikis resistance in endometrial carcinoma.
... response to cytotoxic agents, and modulation of TrkB expression enhanced the sensitivity of cells to cis-Diamminedi- chloroplatinum Cisplatin (CDDP) in head and neck squamous cell carcinoma ...needed ... See full document
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Foxn1 Transcription Factor Regulates Wound Healing of Skin through Promoting Epithelial-Mesenchymal Transition.
... response to injury is followed by a wave of dermal repair ...skin cells and it has been recently reported that only restricted cell lineages mediate scar formation ...Fibroblast-like cells (FSP-1- ... See full document
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Sorafenib ameliorates renal fibrosis through inhibition of TGF-β-induced epithelial-mesenchymal transition.
... inhibits epithelial cancer cell proliferation and EMT ...known to target both Raf and several tyrosine kinases, in- cluding vascular endothelial growth factor R2 (VEGF-R2), platelet-derived growth factor ... See full document
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Inhibition of SK4 Potassium Channels Suppresses Cell Proliferation, Migration and the Epithelial-Mesenchymal Transition in Triple-Negative Breast Cancer Cells.
... aimed to investigate whether SK4 chan- nels affect ...relative to that in non-tumor breast tissues, but there was no apparent expression difference between various subtypes of breast cancer ...MDA-MB-231 ... See full document
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Panepoxydone targets NF-kB and FOXM1 to inhibit proliferation, induce apoptosis and reverse epithelial to mesenchymal transition in breast cancer.
... shown to have increased expression in TNBC tumors and may account for the aggressiveness of these ...reasonable to Figure ...cancer cells. MCF-7, MDA-MB-231, MDA-MB-468 and MDA-MB-453 cells ... See full document
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Myoferlin depletion in breast cancer cells promotes mesenchymal to epithelial shape change and stalls invasion.
... us to examine whether the expression of common epithelial-mesenchymal transition (EMT) markers ...MYOF-KD cells expressed higher levels of the epithelial marked E-cadherin, and ... See full document
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miR-221/222 targets adiponectin receptor 1 to promote the epithelial-to-mesenchymal transition in breast cancer.
... the epithelial-like T47D breast cancer cells, IL6-induced EMT generated CD44+ cells with stem-like properties ...Tumor cells of breast cancer patients that survive after conventional ... See full document
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