[PDF] Top 20 Linaclotide in Chronic Idiopathic Constipation Patients with Moderate to Severe Abdominal Bloating: A Randomized, Controlled Trial.

... of linaclotide did not require patients to meet a minimum thresh- old of abdominal bloating and, in fact, patients had only mild to moderate abdominal ... See full document

... participated in two Genzyme Advisory Board ...prior to this ...Genzyme to his ...adherence to all PLOS One policies on sharing data and ... See full document

... 2008 to May 2010 a total of 236 patients diagnosed with chronic pancreatitis in the last five years in one of both hospitals were screened and 64 patients were ... See full document

... relief with ESWT might be due to stimulation analgesia [24] and increased tissue regeneration ...combined with ESWT relieved chronic low back pain and improved dynamic bal- ance more than ... See full document

... power to detect this interaction. A placebo effect in the active treatment group may also explain this ...participants in the study showed moderate or high levels of physical activity at ... See full document

... double-blind randomized placebo controlled trial, Hypericum perforatum 900 mg daily was less efficacious than placebo and fluoxetine in the treatment of outpatients with mild to ... See full document

... blinded randomized controlled trial with gabapentin in patients that underwent anterior cruciate ligament (ACL) reconstruction ...(1). In their manuscript, the ... See full document

... A randomized controlled trial with a 6-month follow-up period was performed in 70 adults, aged 45 years or older, with type 2 diabetes who were taking insulin and who had an ... See full document

... for randomized controlled trials (RCTs) using as descriptors the keywords: “adalimumab”, “alefacept”, “anakinra”, “briakinumab”, “certolizumab”, “efalizumab”, “etanercept”, “infliximab”, “golimumab”, ... See full document

... (((Randomized controlled trial[pt] OR controlled clinical trial[pt] OR randomized controlled trials[mh] OR random allocation[mh] OR double-blind method[mh] OR single-blind ... See full document

... Complex in patients with rheumatoid arthritis: results at 4-month ...Changes in articular synovial lining volume measured by magnetic resonance in a randomized, double-blind, ... See full document

... A randomized controlled trial of endovascular aneurysm repair versus open surgery for abdominal aortic aneurysms in low to moderate risk ... See full document

... appears to have no significant effect on the outcome of pregnant ...blind, randomized controlled trial con- ducted with pregnant women showed no signifi- cant effect in adverse ... See full document

... 4.5.0.29, with five fields obtained for each slide, and averaged between these measurements. This assessment was made by a single masked observer, which regarded as apoptotic the cells that had three or more of ... See full document

... was to compare the local effect of different approaches for the treatment of moderate to severe generalized chronic periodontitis in type 2 diabetic ...diabetic patients ... See full document

... enrolled in clinical trials comparing hypotonic to isotonic fluids has more than doubled in the last year, and continue to strengthen the evidence in favor of isotonic maintenance ... See full document

... ache, abdominal pain and nausea, not considered clinically signiicant and actually related to the alcohol concentration in the formulation of the phytotherapic ...result in any withdrawn from ... See full document

... up patients along with pa- tients that discontinued treatment during our study period, the observed PASI75 response was ...response to treatment represents the primary predictor of ultimate ... See full document

... biosimilar in 2013, the Portuguese Society of Rheumatology issued a position paper on the use of biosimilars in rheumatic conditions covering efficacy, safety, extrapolation, interchangeability, ... See full document

... small to provide strong inferences regarding the impact of perioperative interventions on perioperative cardiovascular death, nonfatal myocardial infarction, or cardiac arrest in moderate and ... See full document