[PDF] Top 20 The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.
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The mammalian class 3 PI3K (PIK3C3) is required for early embryogenesis and cell proliferation.
... in the later steps of the endocytic pathway [4], and previous work showed that loss of PIK3C3 function results in an accumulation of enlarged vesicles inside cells [14,15,31], we wanted to examine ... See full document
10
The mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortex.
... in the formation of the medial cortex in addition to dramatic changes in the size of the telencephalon at P0 and P14 (Figure ...raise the possibility that the cell ... See full document
13
Requirement of SLD5 for early embryogenesis.
... investigated the function of SLD5 in vivo using gene targeting ...ICM and trophoblast cells in SLD5 2/2 embryos. The GINS complex and CDC45 are involved cooperatively in the initiation ... See full document
8
Mechanical stretch and PI3K signaling link cell migration and proliferation to coordinate epithelial tubule morphogenesis in the zebrafish pronephros.
... proximal-directed cell migration is unknown. Inhibiting proliferation might be expected to cause stretching or breakdown of the distal nephron epithelium, eventually resulting in distortion of ... See full document
11
Prox1 Inhibits Proliferation and Is Required for Differentiation of the Oligodendrocyte Cell Lineage in the Mouse.
... size and reduced accumulation of F4/80+ cells in Prox1-CKO-/- homo- zygous mutants might suggest that the net observed reduction in BrdU+ cells could have been due to a requirement for Prox1 in the ... See full document
19
The Effects of Gender Segregation at the Occupation, Industry, Establishment, and Job-Cell Levels on the Male-Female Wage Gap
... On the firms’ side, the fixed effects absorb unobserved heterogeneity in a large set of factors such as their management productivity, discrimination practices, technologies, job attributes, work ... See full document
23
Flávia da Silva Nader Motta
... into the host bloodstream could hydrolyze host factors, such as hormones, contributing to the development of the disease’s ...present the identification of the ...poptb) and ... See full document
149
SIMPL enhancement of tumor necrosis factor-α dependent p65-MED1 complex formation is required for mammalian hematopoietic stem and progenitor cell function.
... in the p65 generated immunocomplexes and in response to TNFa there was ,2-fold increase in p65-MED1 complex formation ...conditions and relative to the wild-type cells, a more modest increase ... See full document
11
A new combined approach to improved lipid production using a strictly aerobic and oleaginous yeast
... stimulated the aerobic metabolism of ...lipids and cell growth, lipid productivity relates the quantity of lipid synthesized per ...stimulated and reached 0.20 and 0.21 g/L.day, ... See full document
28
Modulation of pilocarpine-induced seizures by cannabinoid receptor 1.
... CP55940, and tetrad behaviors were measured as described by Martin et ...placed 3 cm above the bench surface, with a maximum score of ...performed, and the trial with the longest ... See full document
8
Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.
... to the cytosol as well as to distinct punctae in cytoplasmic protrusions of migrating cells (Figure 5A,B, left ...Rac1 and RhoA localization at cell surfaces facing the wound (Figure 5A,B, ... See full document
15
The 3-hydroxy-2-butanone pathway is required for Pectobacterium carotovorum pathogenesis.
... 3H2B and 23B promote plant growth, drought tolerance, and defense against ...plants and these volatiles were later identified as 3H2B and 23B ...[22]. The plant growth promoting ... See full document
11
U2 snRNP is required for expression of the 3' end of genes.
... hybridization, and analysis HeLa cells (1610 6 cells) were treated with or without 100 ng/ ml of SSA for 4 hours, and RNA was labeled during transcription with 5-ethynyl-uridine (200 m M) between 3 ... See full document
10
The Phosphoinositide 3-Kinase p110α Isoform Regulates Leukemia Inhibitory Factor Receptor Expression via c-Myc and miR-125b to Promote Cell Proliferation in Medulloblastoma.
... regulation is very poorly studied we hypothesized, a c- Myc-dependent indirect control of LIFR expression via ...connecting the microRNA precursor of the let-7 family with c-Myc. The oncogene ... See full document
20
Phosphorylation of Akt and ERK1/2 is required for VEGF-A/VEGFR2-induced proliferation and migration of lymphatic endothelium.
... There is growing evidence that vascular endothelial growth factor-A (VEGF-A), a ligand of the receptor tyrosine kinases VEGFR1 and VEGFR2, promotes ...However, the underlying mechanisms by ... See full document
9
ER Alpha Rapid Signaling Is Required for Estrogen Induced Proliferation and Migration of Vascular Endothelial Cells.
... with, and expand on, our recent studies, which used a dis- rupting peptide to block rapid signaling by inhibiting the interaction between ER and the criti- cal adaptor molecule striatin ... See full document
19
Resistance exercise: A non-pharmacological strategy to minimize or reverse sleep deprivation-induced muscle atrophy
... Testosterone is an anabolic signal molecule, which acts on cell structures stimulating cell ...to the regulation of gene expression and activation of satellite cell, testosterone ... See full document
5
FAMLF is a target of miR-181b in Burkitt lymphoma
... (BL) is a highly malignant non-Hodgkin’s lymphoma that is closely related to the abnormal expression of ...EF413001.1) is a novel gene that was cloned by our research group, and ... See full document
10
An intact centrosome is required for the maintenance of polarization during directional cell migration.
... on cell polarization. A random position in the cytoplasm not containing the centrosome in migrating cells was exposed to the ...illustrates the progression of four control-irradiated ... See full document
12
Phylogenetic relationships and differences in brain structure
... mutant is characterized by an inverse layering of the cortex, in which cells normally belonging to deep layers are lo- cated superficially, and cells normally des- tined to superficial layers are ... See full document
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