[PDF] Top 20 Modulation of invariant natural killer T (INKT)-Cell function in immune-mediated diseases
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Modulation of invariant natural killer T (INKT)-Cell function in immune-mediated diseases
... protection of EAE conferred by anti-CD4 MAb treatment correlated with Foxp3 induction in iNKT ...cells in the cervLNs, but not in the spleen, of immunized ...detected in sick ... See full document
48
Linking inflammation to natural killer T cell activation.
... concentrations in blood and other fluids during chronic inflam- mation, and since Gumperz and colleagues showed that lysopho- spholipids can bind to CD1d molecules previously loaded with other cellular ligands or ... See full document
5
Helicobacter pylori cholesteryl α-glucosides contribute to its pathogenicity and immune response by natural killer T cells.
... Invariant natural killer T (iNKT) cells are recognized as immune cells that react with ...the T cell receptor (TCR) encoded by Va24-Ja18 and Va14-Ja18 rearrangements ... See full document
12
Importance of CD8 T cell-mediated immune response during intracellular parasitic infections and its implications for the development of effective vaccines
... infection of hundreds of millions of individuals every ...host cell cytoplasm that are presented through MHC class I molecules to protec- tive CD8 T ...The in vivo priming ... See full document
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The role of the SLAMSAP signaling pathway in the modulation of CD4+ T cell responses
... surface of hematopoietic cells, can regulate some events of the immune ...capacity of SLAM to interact with an intracytoplasmic adapter, such as SLAM-associated protein ...expressed in ... See full document
8
Paucity of CD4+ natural killer T (NKT) lymphocytes in sooty mangabeys is associated with lack of NKT cell depletion after SIV infection.
... T cell responses by NKT lymphocytes through early IFN-c production during acute virus infection ...antigen-activated T lymphocytes and also acts as the major inducer for the development of ... See full document
13
Neuroantigen-specific autoregulatory CD8+ T cells inhibit autoimmune demyelination through modulation of dendritic cell function.
... model of multiple sclerosis, an immune- mediated demyelinating disorder of the central nervous system ...CD8+ T cells (CNS-CD8+) ameliorate EAE, at least in part through ... See full document
10
A novel mechanism of soluble HLA-G mediated immune modulation: downregulation of T cell chemokine receptor expression and impairment of chemotaxis.
... the function of HLA-F and ...sequence of HLA-class Ia molecules and HLA-G, giving a ‘‘self signal’’ in cells that express HLA-class I molecules, and may have a role in ...a cell ... See full document
13
Immune engagement thresholds for CD8+ T CELL control of yherpesvirus-driven B CELL
... occur in immunosupressed individuals versus those that occur in individuals without overt evidence of immunosuppression (Kutok and Wang, ...lymphoproliferative diseases (PTLDs) in ... See full document
242
Estudo dos repertórios de receptores killer nas células natural Killer e nos linfócitos T do sangue periférico de indivíduos adultos normais
... xvii Cell mediated cytotoxicity has a key role in both adaptive and innate immune responses, especially in the elimination of tumour cells, as well as virus infected ...only ... See full document
171
Modulation of innate antigen-presenting cell function by pre-patent schistosome infection.
... production in response to parasite antigen. Not only is the parasite-specific T cell response down modulated [30], but so is the overall T cell response that is elicited by polyclonal ... See full document
14
THE ROLE OF ANTIGEN PRESENTING CELLS IN IMMUNE REGULATION MEDIATED BY REGULATORY T CELLS
... described in figure 4. Briefly, DC were isolated from spleens of WT syngeneic ...Half of the DC were loaded with OVA peptide and labeled with ...2.5mM of CFSE (CFSE lo ...groups of ... See full document
138
Safety of Anti-TNF Therapies in Immune-Mediated Inflammatory Diseases: Focus on Infections and Malignancy
... IR of active tuberculosis, in the Portuguese general population, was 25 (22-28) per ...population in 2015 ...found in this group of patients treated with ...engaged. In fact 80% ... See full document
86
Glycans as Key Checkpoints of T Cell Activity and Function
... a cell surface inhibitory T cell receptor responsible for immune-inhibitory responses associated with the so-called “T cell exhaustion” ...expression of this cell ... See full document
13
Evolution of male-killer suppression in a natural population.
... occurrence of infected males in Borneo represents presence of the same suppressor elements demonstrated in Philippine/Thai ...matter in a highly migratory species such as ...episode ... See full document
6
RECETORES KILLAR NOS LINFÓCITOS T E NAS CÉLULAS NATURAL KILLER EM DOENTES COM ESCLEROSE MÚLTIPLA
... Atualmente, o único fator genético de suscetibilidade para o desenvolvimento da EM é o haplótipo DRB1*1501-DQA1*0102-DQB1*0602 do HLA II (Gödde et al., 2005). Estudos recentes indicam um efeito protetor de alguns alelos ... See full document
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CO-mediated cytoprotection is dependent on cell metabolism modulation
... required in nitric oxide (NO) synthesis in endothelial cells ...factor. In a recent paper, Almeida and colleagues used human neuroblastoma SH-SY5Y cells as models for neuronal dif- ferentiation and ... See full document
10
Mechanistic model of natural killer cell proliferative response to IL-15 receptor stimulation.
... NK cell prolifer- ation at a cellular level, we developed a mathematical model incorporating IL-15R binding and trafficking parameters that modulate IL-15/IL-15R complex ...NK cell population dynamics and ... See full document
16
Participation of leukotrienes in the immune modulation of oral tolerance
... involved in the physiopathology of this asthma ...present in several immune responses; we studied the release of the same in animals’ leukotriene deficient in the TOL ... See full document
7
Exploring the role of O-Mannosylation in the modulation of E-Cadherin function in Gastric Cancer cell line models
... absence of a wild type (WT) E-Cad, with decreased cell-cell adhesion and increased cellular motility 31-37 ...hypermethylation in a CpG island of one 5’-CDH1 promoter 38 , are ... See full document
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