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[PDF] Top 20 Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cells.

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Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cells.

Profiling gene expression induced by protease-activated receptor 2 (PAR2) activation in human kidney cells.

... PAR2 activation in physiology and ...PAR2 activation is self- sustaining and strongly implicated in cell metabolism, proliferation and ...PAR2 in metabolism and metabolic ... See full document

14

Protease-activated receptor 2 mediates mucus secretion in the airway submucosal gland.

Protease-activated receptor 2 mediates mucus secretion in the airway submucosal gland.

... to human tracheal mucosa markedly increased glandular secretion, resulting in bubble formation that was comparable to the response achieved with carbachol (10 m M), a potent cholinergic ...stimulation ... See full document

8

Increased expression of protease-activated receptor 4 and Trefoil factor 2 in human colorectal cancer.

Increased expression of protease-activated receptor 4 and Trefoil factor 2 in human colorectal cancer.

... involved in polygenetic alterations in prooncogenes and/or tumor suppressor genes, and aberrant epigenetic gene regulation can lead to abnormal growth of malignant tumors ...involved in tumor ... See full document

14

Glucocorticoid-induced reversal of interleukin-1β-stimulated inflammatory gene expression in human oviductal cells.

Glucocorticoid-induced reversal of interleukin-1β-stimulated inflammatory gene expression in human oviductal cells.

... up-regulated in several cancers, most notably colorectal carcinoma ...cytokine expression to promote the inflammatory response, which could contribute to ...and 2, may exert a protective effect for ... See full document

11

Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells.

Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells.

... Differential expression of KLK1 has been identified in several cancers and other diseases ...mediated by kinin receptor B1R and B2R signaling, other studies demonstrated that KLK can ... See full document

11

The role of Omi/HtrA2 protease in neonatal postasphyxial serum-induced apoptosis in human kidney proximal tubule cells

The role of Omi/HtrA2 protease in neonatal postasphyxial serum-induced apoptosis in human kidney proximal tubule cells

... role in the translocation of Omi/HtrA2 from the mitochon- dria to the ...cytoplasm. In renal ischemia/reper- fusion, TNF-α gene transcription is primarily regulated by NF-κB activation ... See full document

10

Investigation of variation in gene expression profiling of human blood by extended principle component analysis.

Investigation of variation in gene expression profiling of human blood by extended principle component analysis.

... Eigen-R 2 method, our result demonstrated that the heteroge- neity of white blood cell constituents indeed contributed to the most significant portion of the overall data ...the gene- wise linear analysis ... See full document

11

Profiling of olfactory receptor gene expression in whole human olfactory mucosa.

Profiling of olfactory receptor gene expression in whole human olfactory mucosa.

... a gene is expressed, it is more likely to be ...neurons in the olfactory bulb and therefore reduces the survival of these neurons ...and expression could be further explored by studying the ... See full document

14

Peroxiredoxin 5 Protects TGF-β Induced Fibrosis by Inhibiting Stat3 Activation in Rat Kidney Interstitial Fibroblast Cells.

Peroxiredoxin 5 Protects TGF-β Induced Fibrosis by Inhibiting Stat3 Activation in Rat Kidney Interstitial Fibroblast Cells.

... Aberrant activation of fibroblasts to myofibroblasts is one of the hallmarks of renal fibrosis in chronic kidney diseases such as diabetes mellitus and ...hypertension. Activated ... See full document

14

Gene expression profiling associated with angiotensin II type 2 receptor-induced apoptosis in human prostate cancer cells.

Gene expression profiling associated with angiotensin II type 2 receptor-induced apoptosis in human prostate cancer cells.

... stimulated by TRAIL at the cell-surface, fulfils a distinct function in the nucleus where it promotes cell proliferation in a TRAIL-independent manner suggests a specific, proliferation- associated ... See full document

12

Regulation and gene expression profiling of NKG2D positive human cytomegalovirus-primed CD4+ T-cells.

Regulation and gene expression profiling of NKG2D positive human cytomegalovirus-primed CD4+ T-cells.

... Recombinant human TNF-a and IL-15 were purchased from ...provided by Dr. Federica Sallusto (Institute for Research in Biomedicine, Bellinzona, ...of cells for cytokine measurements and/or for ... See full document

14

Activation of mu or delta opioid receptors in the lumbosacral spinal cord is essential for ejaculatory reflexes in male rats.

Activation of mu or delta opioid receptors in the lumbosacral spinal cord is essential for ejaculatory reflexes in male rats.

... opioid receptor antagonist CTOP and delta opioid receptor antagonist TIPP did not block ejaculation by preventing the activation of LSt cells, expression of phosphoryla- tion of ... See full document

18

Granzyme K activates protease-activated receptor-1.

Granzyme K activates protease-activated receptor-1.

... GrK in disease, this is the first study to demonstrate a physiological role for extracellular GrK in cytokine ...proliferation in lung fibroblasts is significant given recent observations that ... See full document

9

Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cells.

Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cells.

... expressed in the two cell populations) after screening of 13925 genes (Figure ...progenitor cells highly and predominantly expressed chemokine ligands such as CXCL1, CXCL3, CXCL5, CXCL6 and CXCL7 when ... See full document

11

Increased expression of tissue factor and protease-activated receptor-1 does not correlate with thrombosis in human lung adenocarcinoma

Increased expression of tissue factor and protease-activated receptor-1 does not correlate with thrombosis in human lung adenocarcinoma

... and activation of PAR-1, a G-protein-coupled receptor ...described in several types of tumor including breast, colon, melanoma, and esophageal cancer ...PAR-1 expression as a negative ... See full document

7

Transcriptional dysregulation in NIPBL and cohesin mutant human cells.

Transcriptional dysregulation in NIPBL and cohesin mutant human cells.

... included in the whole genome expression array studies as described above; the third proband CDL-017 has a mutation in the SMC1A gene and manifests a much milder phenotype (Tables S1 and ... See full document

16

INFLUENCE OF THYROID HORMONES ON MYOCARDIAL METABOLIC PROCESSES

INFLUENCE OF THYROID HORMONES ON MYOCARDIAL METABOLIC PROCESSES

... Молочная ислота в норме обеспечивает о оло 25% энер етичес их потребностей мио арда [26]. Ла тат, а и е о о исленная форма — пировино - радная ислота — пост пает в лет при помощи моно арбо силатно о транспортера 1 типа ... See full document

5

The transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cells.

The transcription factor SOX18 regulates the expression of matrix metalloproteinase 7 and guidance molecules in human endothelial cells.

... molecules in endothelial cells. EFNB2 and its counter-receptor EPHB4 are expressed on developing arteries and veins respectively, and repulsive signaling between the two molecules has been suggested ... See full document

9

RANK, RANKL and osteoprotegerin in arthritic bone loss

RANK, RANKL and osteoprotegerin in arthritic bone loss

... characterized by the presence of inflamma- tory synovitis and destruction of joint cartilage and ...released by synovia, chondrocytes and pannus can cause cartilage destruction and cytokine-activated ... See full document

10

PTH1 receptor is involved in mediating cellular response to long-chain polyunsaturated fatty acids.

PTH1 receptor is involved in mediating cellular response to long-chain polyunsaturated fatty acids.

... MC3T3-E1 cells do express endogenous PTH1R [45]). In untransfected HEK293 cells, no significant increase in ERK1/2 phosphorylation was found compared to non- treated cells ... See full document

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