[PDF] Top 20 The Roles of ROS in Cancer Heterogeneity and Therapy
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The Roles of ROS in Cancer Heterogeneity and Therapy
... observed in tumor cells are different from the normal ...most of the energetic supply of cancer cells occurs through increasing rate of glycolysis followed by oxidation ... See full document
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The role of mammographic calcification in the neoadjuvant therapy of breast cancer imaging evaluation.
... All of the digital imaging results were preserved in the PACS image system ...Pre- and post-chemotherapy MGs were assessed retrospectively, both in CC and MLO ...assess ... See full document
7
Glycosylation in cancer: Selected roles in tumour progression, immune modulation and metastasis
... by the need to overcome the rapidly evolving sialome of the host ...either in cis or trans and have one or more tyrosine- based signalling motifs in their cytoplasmatic ... See full document
31
G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy.
... consists of three functional proto-oncogenes (HRAS, NRAS and KRAS) that encode for guanine-binding proteins sharing a high homology (p21 RAS ) ...on the inner cell membrane through a farnesyl group ... See full document
15
Targeting nucleocytoplasmic transport in cancer therapy
... suppressors and oncogenic proteins is tightly regulated and essential for their ...Because the deregulation of intracellular protein transport is crucially involved in the ... See full document
18
Perspectives of Dendrimer-based Nanoparticles in Cancer Therapy
... effect of increased permeability and retention (EPR) (Maeda et ...2000). The amount of the delivery system based on dendrimers, which accumulates in tumor tissue is influenced by ... See full document
16
Roles of ApoB-100 gene polymorphisms and the risks of gallstones and gallbladder cancer: a meta-analysis.
... GS and GBC. A variety of epidemiological studies have been performed to explore the associations between several candidate genes and the risks of GS and ...is of ... See full document
9
Design and production of new nanodevices for future application in cancer therapy
... defective and endothelial cells disorganized with large fenestrations, results in extensive leakage of blood plasma components into the ...help the retention of nanoparticles ... See full document
87
Differential Predictive Roles of A- and B-Type Nuclear Lamins in Prostate Cancer Progression.
... Prostate cancer (PCa) is the most common malignancy among men and a remarkable public health challenge in Western ...countries. In United States, more than 230 000 new cases and ... See full document
16
Investigating the Influence of Group Therapy with Logo Therapy Approach in Reducing Depression in Patients with Colorectal Cancer
... was in line with research of Pirkhaleghi and Salehi (2013) as meaning of the effectiveness of group therapy on mental health promotion for women with breast cancer ... See full document
7
Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation.
... crucial in determining whether the autophagic cargo and assembly finally reaches the lysosomes and is subsequently ...One of the ways to determine autophagic flux is ... See full document
12
Novel predictive markers of therapy response in gastric cancer
... from the results obtained in the present study. However, in that study, cell response to treatment was evaluated through apoptosis assays, while in the current study cell ... See full document
105
Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.
... Present in Pre-Treatment Disease The survival analyses suggested that the degree of CE could have effects on PFS and OS consis- tent with the hypothesis that cancers with high CE ... See full document
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The role of YB‐1 in acquired resistance to hormone therapy in breast cancer
... 70% of all BC express HR, ER and/or PR, detected by immunohistochemistry (IHC), which led to the development of hormone therapy (HT) ...methods. The first being used was ovarian ... See full document
31
SERPINA3K plays antioxidant roles in cultured pterygial epithelial cells through regulating ROS system.
... activity in the cornea. Here we investigated the antioxidant effects of SERPINA3K on the pterygial, which is partially caused by oxidative stress in ...pathogenesis. The ... See full document
8
Cancer gene therapy
... resuspended in 10 mL of P1 buffer (50 mM of Tris-HCl at pH = ...mM of EDTA hydrated and 100 μg/mL RNase A) and then in 10 mL of P2 buffer (200 mM of NaOH ... See full document
86
Cancer stem cells in prostate cancer: implications for targeted therapy
... Cancer is recognized as a heterogeneous disease with a variety of ...This heterogeneity is an intrinsic characteristic that contributes to therapy ...One the- ory that explains tumor ... See full document
12
Pivotal Roles of Glucocorticoids in the Pathogenesis and Treatment of Inflammatory
... effective in the treatment of a variety of inflammatory and auto-immune con- ditions, including rheumatoid arthritis ...clinical and biological mar- kers of inflammation ... See full document
7
INDUCING APOPTOSIS IN CANCER THERAPY
... Inhibition of FLIP expression in tumour cells might be of particular importance for TNF-rela- ted apoptosis-inducing ligand (TRAIL)-based cancer ...is the ligand of two death ... See full document
5
Intratumoral Heterogeneity of MicroRNA Expression in Rectal Cancer.
... In the present study it was possible to visualise the cellular localisation of the investigated miRNAs, and the corresponding ISH signal allowed for focus on the ... See full document
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