[PDF] Top 20 Targeting Tumor Microenvironment for Cancer Therapy
Has 6182 "Targeting Tumor Microenvironment for Cancer Therapy" found on our website. Below are the top 20 most common "Targeting Tumor Microenvironment for Cancer Therapy".
Targeting Tumor Microenvironment for Cancer Therapy
... for cancer treatment [ 16 ...and tumor cells progressed, different combinatory approaches were defined to target the different cells within the TME at the same time based on the assumption that modulating ... See full document
31
Production and characterization of S100A4- targeting nanorods for an anti-cancer thermal ablation therapy
... mentioned cancer tumors are not only composed of cancer cells and the metastatic spread requires the cooperation of normal host cells such as endothelial cells, fibroblasts, other mesenchymal cells, and ... See full document
71
Feasibility Study of EndoTAG-1, a Tumor Endothelial Targeting Agent, in Combination with Paclitaxel followed by FEC as Induction Therapy in HER2-Negative Breast Cancer.
... Ktrans tumor perfusion at the end of EndoTAG-1/Paclitaxel administration was also noted among 13 patients with available infor- mation about MRI-estimated Ktrans tumor perfusion (median change %, 36%, ... See full document
11
The MicroRNA-217 Functions as a Potential Tumor Suppressor in Gastric Cancer by Targeting GPC5.
... Samples of human GC tissues and paired-adjacent non-tumor gastric tissues that were farther than 5 cm from the tumors were obtained from 50 patients who underwent surgery resection at the The Affiliated YanAn ... See full document
12
Reversing the intractable nature of pancreatic cancer by selectively targeting ALDH-high, therapy-resistant cancer cells.
... ALDH-high cancer cells derived from human PDAC cell ...of tumor growth, and failed to achieve an actual reduction in the size of ...of cancer cells, the ALDH-low portion was not affected and ... See full document
11
Targeting Artificial Tumor Stromal Targets for Molecular Imaging of Tumor Vascular Hypoxia.
... of tumor hypoxia detection methods have been inconsistent in their ability to predict treatment outcomes or monitor treatment efficacy, limiting their present prognostic ...global tumor oxygenation lev- els ... See full document
12
Developments in tumor targeting and internalizing peptides
... tumors, cancer cells are surrounded by a complex microenvironment with unique physicochemical properties, since the fast tumor growth demands a higher consumption of energy and oxygen, leading to ... See full document
62
Favorable alteration of tumor microenvironment by immunomodulatory cytokines for efficient T-cell therapy in solid tumors.
... control tumor growth even in mice, as B16.OVA tumor-bearing mice treated with T-cells only displayed poor growth inhibition (Fig ...T-cell therapy is the result of an imbalance between the number ... See full document
20
Lignin nanoparticles for cancer therapy
... The antiproliferative effect of the BZL-loaded CLNPs was studied after the loading capacity of BZL into CLNPs and their release profiles were evaluated. BZL inhibits the oncogenic Pim kinases that are often overexpressed ... See full document
71
Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT.
... that tumor-associated fibroblasts, inflammatory cells, cytokines and EMT in tumor biology are potential factors that enable cancer cell invasion, metastasis and malignancy and this process is ... See full document
15
The ADMR receptor mediates the effects of adrenomedullin on pancreatic cancer cells and on cells of the tumor microenvironment.
... vivo targeting of ADMR using DOPC nanoliposome coupled human and mouse siADMR in ...pancreatic cancer cells (MPanc96 with luciferase gene) and monitored for a period of six ...in tumor volume as ... See full document
12
Rosamines targeting the cancer oxidative phosphorylation pathway.
... to cancer, so mitochondria are potential targets for anticancer ...a tumor allografted mouse ...colorectal cancer sub-panel than other cell ...breast cancer-bearing female BALB/c mice ... See full document
10
Signaling pathways influencing tumor microenvironment and their exploitation for targeted drug delivery
... ventional cancer drugs but also for gene therapy, which stands as an attractive therapeutic approach for ...gene therapy, functional DNA molecules or small inter- fering RNA (siRNA) are effectively ... See full document
29
Inhibition of mesothelin as a novel strategy for targeting cancer cells.
... to tumor necrosis factor alpha (TNF-alpha) ...for tumor-specific ...of cancer cells remains to be ...in cancer cells derived from mesothelioma, pancreatic and ovarian ...of cancer cells ... See full document
11
Colorectal tumor microenvironment: unravelling the interplay between macrophages and the extracellular matrix
... formed tumor vessels do not exhibit a hierarchical organization but, instead, have irregular branching patterns, altered lumen sizes and chaotic distribution ...and tumor cell-derived cytokines, namely ... See full document
178
Targeting of human CD44v6 with engineered nanoparticles for gastrointestinal cancer diagnosis and therapy
... When Orian-Rousseau et al. (2002) identified that c-Met activation by HGF required presentation by CD44v6, they were able to inhibit that activation using mAbs directed towards specific CD44v6 epitopes [10]. Mutating ... See full document
125
Targeting nucleocytoplasmic transport in cancer therapy
... the cancer predisposing mechanism ...in cancer. In light of these reports, it is thought that tumor suppression breaks down when the cell is no longer capable of shuttling cyclin D1 from the ... See full document
18
Nanotheranostics Targeting the Tumor Microenvironment
... of cancer cell lines on microfluidic devices led to the construction of tumor-on-a- chip models (ToC), also called ...co-culture cancer cells with endothelial cells, thus facilitating the study of ... See full document
18
In silico experimentation of glioma microenvironment development and anti-tumor therapy.
... of tumor microenvironment integrate informa- tion about the biological context in which cancers develop, and thus represent a multi-scale consideration of oncogenesis as it occurs within somatic tissues ... See full document
10
Targeting the NF-κB Pathway as a Combination Therapy for Advanced Thyroid Cancer.
... thyroid cancer (PTC) cell line BCPAP and three ATC cell lines 8505C, THJ16T and SW1736 that have been validated by short tandem repeat profiling ...Motif). Tumor necrosis factor α (TNFα) was used as a ... See full document
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