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Substrate-driven mapping of the degradome by comparison of sequence logos.

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Academic year: 2017

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Figure 4. Protease specificity tree over the non-prime binding site region S4-S1: The degradome is mapped to a protease specificity tree based on local substrate similarity over S4-S1 pockets
Figure 6. Mapping of known targets of benzamidine to the substrate-driven protease specificity tree: Known targets from the ChEMBL database (outer ring blue) cluster on top of the protease specificity tree based on S4-S1 substrate readout compared to unkno

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