تأثیر بوی وانیل بر پاسخ به درد ناشی از خونگیری وریدی در نوزادان نارس: کارآزمایی بالینی شاهددار تصادفی

(1)

ﺪﻫﺍﻮﺷ ﺮﺑ ﻲﻨﺘﺒﻣ ﺖﺒﻗﺍﺮﻣ ﻪﻣﺎﻨﻠﺼﻓ /

ﻩﺭﺎﻤﺷ ،ﻡﺭﺎﻬﭼ ﻩﺭﻭﺩ 11

ﻥﺎﺘﺴﺑﺎﺗ ، 93

/ http://ebcj.mums.ac.ir

ﺗﺄ

ﺦﺳﺎﭘ ﺮﺑ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﺮﻴﺛ

ﺯﺍ ﻲﺷﺎﻧ ﺩﺭﺩ ﻪﺑ

ﻥﻮﺧ

ﻱﺮﻴﮔ

ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ ﺭﺩ ﻱﺪﻳﺭﻭ

:

ﻲﻨﻴﻟﺎﺑ ﻲﻳﺎﻣﺯﺁﺭﺎﻛ

ﺪﻫﺎﺷ

ﻲﻓﺩﺎﺼﺗ ﺭﺍﺩ

ﻲﻠﻴﺋﺮﺒﺟ ﺯﺎﻨﻬﻣ

1

ﻲﻟﻮﺳﺭﺪﻴﺳ ﻪﻬﻟﺁ ،

2

ﻩﺩﺍﺯﺎﺟﻮﻗ ﻲﻀﺗﺮﻣ ،

3

ﻲﻨﻴﺴﺣ ﺮﻗﺎﺑﺪﻤﺤﻣ ،

4

ﻪﺸﻴﻤﻫ ﺪﻣﺎﺣ ، ﺭﺎﻛ

5

، * ﻲﻧﻼﻬﻔﺳﺍ ﻁﺎﺸﻧ ﻪﻴﻧﺎﻫ

6

1 . ،ﻥﺎﻛﺩﻮﻛ ﻱﺭﺎﺘﺳﺮﭘ ﻩﻭﺮﮔ ﻲﺑﺮﻣ ﻭ ﻱﺭﺎﺘﺳﺮﭘ ﻩﺪﻜﺸﻧﺍﺩ

ﻲﻜﺷﺰﭘ ﻡﻮﻠﻋ ﻩﺎﮕﺸﻧﺍﺩ ،ﻲﻳﺎﻣﺎﻣ ﺰﻳﺮﺒﺗ

، ﺰﻳﺮﺒﺗ ﻥﺍﺮﻳﺍ ،

2 . ﺰﻳﺮﺒﺗ ،ﺰﻳﺮﺒﺗ ﻲﻜﺷﺰﭘ ﻡﻮﻠﻋ ﻩﺎﮕﺸﻧﺍﺩ ،ﻲﻳﺎﻣﺎﻣ ﻭ ﻱﺭﺎﺘﺳﺮﭘ ﻩﺪﻜﺸﻧﺍﺩ ،ﻲﺣﺍﺮﺟ ﻲﻠﺧﺍﺩ ﻱﺭﺎﺘﺳﺮﭘ ﻩﻭﺮﮔ ﻲﺑﺮﻣ ﺍ ،

ﻥﺍﺮﻳ

3 . ﺰﻳﺮﺒﺗ ،ﺰﻳﺮﺒﺗ ﻲﻜﺷﺰﭘ ﻡﻮﻠﻋ ﻩﺎﮕﺸﻧﺍﺩ ،ﻲﻜﺷﺰﭘ ﻩﺪﻜﺸﻧﺍﺩ ،ﻱژﻮﻟﻮﻳﺰﻴﻓ ﺭﺎﻴﺸﻧﺍﺩ ﺍ ،

ﻥﺍﺮﻳ

4 . ﭘ ﻩﺪﻜﺸﻧﺍﺩ ،ﻥﺎﻛﺩﻮﻛ ﻩﻭﺮﮔ ﺭﺎﻴﺸﻧﺍﺩ ﺰﻳﺮﺒﺗ ،ﺰﻳﺮﺒﺗ ﻲﻜﺷﺰﭘ ﻡﻮﻠﻋ ﻩﺎﮕﺸﻧﺍﺩ ،ﻲﻜﺷﺰ

ﺍ ، ﻥﺍﺮﻳ

5 . ﻥﺍﺮﻳﺍ ،ﺰﻳﺮﺒﺗ ،ﺰﻳﺮﺒﺗ ﻲﻜﺷﺰﭘ ﻡﻮﻠﻋ ﻩﺎﮕﺸﻧﺍﺩ ،ﻭﺭﺍﺩ ﺕﺎﻘﻴﻘﺤﺗ ﺰﻛﺮﻣ ﺭﺎﻳﺩﺎﺘﺳﺍ

6 .. ﻥﺍﺮﻳﺍ ،ﺰﻳﺮﺒﺗ ،ﺰﻳﺮﺒﺗ ﻲﻜﺷﺰﭘ ﻡﻮﻠﻋ ﻩﺎﮕﺸﻧﺍﺩ ،ﻲﻳﺎﻣﺎﻣ ﻭ ﻱﺭﺎﺘﺳﺮﭘ ﻩﺪﻜﺸﻧﺍﺩ ،ﻱﺭﺎﺘﺳﺮﭘ ﺪﺷﺭﺍ ﻲﺳﺎﻨﺷﺭﺎﻛ ﻱﻮﺠﺸﻧﺍﺩ

* ﻝﻭﺆﺴﻣ ﻩﺪﻨﺴﻳﻮﻧ :

ﺮﺷ ﻥﺎﺑﺎﻴﺧ ﻱﺎﻬﺘﻧﺍ ،ﺰﻳﺮﺒﺗ ،ﻲﺘﻌﻳ

ﻲﻳﺎﻣﺎﻣ ﻭ ﻱﺭﺎﺘﺳﺮﭘ ﻩﺪﻜﺸﻧﺍﺩ

ﻚﻴﻧﻭﺮﺘﻜﻟﺍ ﺖﺴﭘ :

hanie.neshat@yahoo.com

ﻩﺪﻴﻜﭼ ﻪﻣﺪﻘﻣ :

ﻪﻛ ﺖﺳﺍ ﻩﺩﺍﺩ ﻥﺎﺸﻧ ﺕﺎﻌﻟﺎﻄﻣ ﻭ ﻡﺮﺗ ﻥﺍﺩﺍﺯﻮﻧ

ﻭﺩ ﺮﻫ ﺱﺭﺎﻧ ﻪﻛ ﺪﻨﺘﺴﻫ ﺭﺩﺎﻗ

ﺮﻃﺎﺧ ﻪﺑ ﺍﺭ ﻲﻄﻴﺤﻣ ﻱﺎﻫﻮﺑ ﻭ ﺪـﻧﺭﻭﺎﻴﺑ ﺩﺎـﻳ ﻪﺑ ﺩﺪﺠﻣ ﻩﺩﺮﭙﺳ

ﺭﺩ ﻲﻳﻭﺭﺍﺩﺮﻴﻏ ﺵﻭﺭ ﻚﻳ ﻥﺍﻮﻨﻋ ﻪﺑ ﺪﻧﺍﻮﺗ ﻲﻣ ﻲﻳﺎﻳﻮﺑ ﻩﺮﻃﺎﺧ ﻦﻳﺍ ﺪﺷﺎﺑ ﺮﺛﺆﻣ ﺎﻬﻧﺁ ﺩﺭﺩ ﻝﺮﺘﻨﻛ

.

ﻑﺪﻫ :

ﺗ ﻦﻴﻴﻌﺗ ﺄ ﺯﺍ ﻲﺷﺎﻧ ﺩﺭﺩ ﻪﺑ ﺦﺳﺎﭘ ﺮﺑ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﺮﻴﺛ ﻥﻮﺧ

ﻱﺮﻴﮔ ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ ﺭﺩ ﻱﺪﻳﺭﻭ .

ﺵﻭﺭ :

ﻲﻨﻴﻟﺎﺑ ﻲﻳﺎﻣﺯﺁﺭﺎﻛ ﻪﻌﻟﺎﻄﻣ ﻚﻳ ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ ﺪﻫﺎﺷ

ﻲﻣ ﻲﻓﺩﺎﺼﺗ ﺭﺍﺩ ﺪﺷﺎﺑ

؛ ﻥﺁ ﺭﺩ ﻪﻛ ، 90 ﻲﻓﺩﺎـﺼﺗ ﺭﻮـﻃ ﻪـﺑ ﻂﻳﺍﺮـﺷ ﺪـﺟﺍﻭ ﺱﺭﺎﻧ ﺩﺍﺯﻮﻧ

ﻩﻭﺮﮔ ﻭﺩ ﻪﺑ ﻭ ﺏﺎﺨﺘﻧﺍ 45

ﺘﻨﻛ ﻱﺮﻔﻧ ﺪﻧﺪﺷ ﻢﻴﺴﻘﺗ ﻪﻠﺧﺍﺪﻣ ﻭ ﻝﺮ .

،ﻪﻠﺧﺍﺪﻣ ﻩﻭﺮﮔ ﻥﺍﺩﺍﺯﻮﻧ 5

ﺯﺍ ﻞﺒﻗ ﻪﻘﻴﻗﺩ ﻥﻮﺧ

ﻱﺮﻴﮔ ﺎﺗ 30 ﻥﺁ ﻡﺎـﻤﺗﺍ ﺯﺍ ﺲﭘ ﻪﻴﻧﺎﺛ ،

ﻮﺒﺳﻼﭘ ﻱﻮﺑ ﺽﺮﻌﻣ ﺭﺩ ﻝﺮﺘﻨﻛ ﻩﻭﺮﮔ ﻥﺍﺩﺍﺯﻮﻧ ﻭ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﺽﺮﻌﻣ ﺭﺩ )

ﺮﻄﻘﻣ ﺏﺁ ( ﺪﻨﺘﻓﺮﮔ ﺭﺍﺮﻗ .

ﺭﺩ ﻥﺍﺩﺍﺯﻮﻧ ﺩﺭﺩ ﺭﺍﺰـﺑﺍ ﺯﺍ ﻩﺩﺎﻔﺘـﺳﺍ ﺎﺑ ﻩﻭﺮﮔ ﻭﺩ ﺮﻫ

ﺱﺭﺎﻧ ﺩﺍﺯﻮﻧ ﺩﺭﺩ ﺶﺠﻨﺳ )

PIPP

( 30 ﺎﺛ ﻭ ﻦﻴﺣ ،ﻞﺒﻗ ﻪﻴﻧ 30

ﻪﻴﻧﺎﺛ ﻡﺎﻤﺗﺍ ﺯﺍ ﺲﭘ ﻥﻮﺧ

ﻱﺮﻴﮔ ﻩﺯﺍﺪﻧﺍ ﺪﺷ ﻱﺮﻴﮔ . ﻩﺩﺍﺩ ﻞﻴﻠﺤﺗ ﻡﺮﻧ ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﺎﺑ ﺎﻫ

ﺭﺍﺰﻓﺍ

SPPS

ﺶﻳﺍﺮﻳﻭ 16 ﻥﻮﻣﺯﺁ ﻭ ﻲﺗ ﻱﺎﻫ ﻩﺯﺍﺪﻧﺍ ﺡﺮﻃ ﻭ ﻱﺎﻛﺭﻭﺬﺠﻣ ،ﻞﻘﺘﺴﻣ ﻱﺮﻴﮔ

ﺖﻓﺮﻳﺬﭘ ﺕﺭﻮﺻ ﻪﻠﻣﺎﻋﺪﻨﭼ ﺭﺮﻜﻣ ﻱﺎﻫ .

ﻪﺘﻓﺎﻳ ﺎﻫ :

ﻲﻠﻋ ﺯﺍ ﺲﭘ ﻭ ﻦﻴﺣ ﺩﺭﺩ ﻩﺮﻤﻧ ﻦﻴﺑ ﺕﻭﺎﻔﺗ ﺩﻮﺟﻭ ﻢﻏﺭ ﻥﻮﺧ

ﺮﻴﮔ ﻱ ﻲﻨﻌﻣ ﻑﻼﺘﺧﺍ ﻩﺪﻣﺁ ﺖﺳﺩ ﻪﺑ ﻱﺭﺎﻣﺁ ﺞﻳﺎﺘﻧ ،ﻩﻭﺮﮔ ﻭﺩ ﺭﺩ ﻥﺎﺸﻧ ﺍﺭ ﻱﺭﺍﺩ

ﺩﺍﺪﻧ ) 36 /0

p= (.

ﻪﺠﻴﺘﻧ ﻱﺮﻴﮔ :

ﻪﻛ ﺩﺍﺩ ﻥﺎﺸﻧ ﻪﻌﻟﺎﻄﻣ ﺞﻳﺎﺘﻧ ﺯﺍ ﻲﺷﺎﻧ ﺩﺭﺩ ﺶﻫﺎﻛ ﺮﺑ ﻞﻴﻧﺍﻭ ﻱﻮﺑ

ﻥﻮﺧ ﻱﺮﻴﮔ ﺭﺩ ﻱﺪﻳﺭﻭ ﺗ ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ

ﺄ ﺩﺭﺍﺪﻧ ﻱﺮﻴﺛ .

ﻩژﺍﻭﺪﻴﻠﻛ ﺎﻫ :

،ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﻥﻮﺧ

ﻱﺮﻴﮔ ﻱﺪﻳﺭﻭ ، ﺩﺍﺯﻮﻧ ،ﺩﺭﺩ ﺱﺭﺎﻧ

ﺦﻳﺭﺎﺗ ﺖﻓﺎﻳﺭﺩ : 23 / 11 / 1392

ﺵﺮﻳﺬﭘ ﺦﻳﺭﺎﺗ :

(2)

ﻪﻣﺪﻘﻣ

ﻲﻣ ﻩﺪﺷ ﺕﺎﺒﺛﺍ ﻱﺮﻣﺍ ﻥﺁ ﻪﺑ ﺦﺳﺎﭘ ﻭ ﺩﺭﺩ ﺯﺍ ﺩﺍﺯﻮﻧ ﻙﺭﺩ ﻩﺯﻭﺮﻣﺍ ﺪﺷﺎﺑ

)1 ( . ﺕﺎﻌﻟﺎﻄﻣ 15 ﻩﺩﺍﺩ ﻥﺎﺸﻧ ﺮﻴﺧﺍ ﻝﺎﺳ ﺍ

ﺖﺳ ﻞﺒﻗ ﺱﺭﺎﻧ ﺩﺍﺯﻮﻧ ﻪﻛ

ﻪﺘﻔﻫ ﺯﺍ 26 ﻲﻣ ﺩﺭﺩ ﺱﺎﺴﺣﺍ ﻪﺑ ﺭﺩﺎﻗ ﻲﮕﻠﻣﺎﺣ ﺑ

ﺪﺷﺎ )2 ( . ﻥﺍﺩﺍﺯﻮﻧ

ﻱﺎﻫﺯﻭﺭ ﺭﺩ ﺱﺭﺎﻧ ﺖﺒﻗﺍﺮﻣ ﺶﺨﺑ ﺭﺩ ﺩﻮﺧ ﻲﮔﺪﻧﺯ ﻦﻳﺯﺎﻏﺁ

ﻱﺎﻫ

ﻥﺍﺩﺍﺯﻮﻧ ﻩﮋﻳﻭ )

NICU

( ﺖﺤﺗ ءﺎﻘﺑ ﻆﻔﺣ ﺭﻮﻈﻨﻣ ﻪﺑ ﺕﻼﺧﺍﺪﻣ

ﻱﺩﺪﻌﺘﻣ ﻲﻣ ﺭﺍﺮﻗ ﺪﻧﺮﻴﮔ ﻲﻣ ﻪﺑﺮﺠﺗ ﺭﺮﻜﻣ ﺕﺭﻮﺻ ﻪﺑ ﺍﺭ ﺩﺭﺩ ﻭ ﺪﻨﻨﻛ

؛

ﺩﺭﺩﺪﺿ ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﻥﻭﺪﺑ ﺕﻼﺧﺍﺪﻣ ﻦﻳﺍ ﺯﺍ ﻲﺧﺮﺑ ﻪﻛ ﻡﺎﺠﻧﺍ ﻲﻣ ﺷ ﻮ ﺩ )3 ( . ﻥﻮﺧ ﻱﺮﻴﮔ ﻪﻠﺧﺍﺪﻣ ﻥﺍﻮﻨﻋ ﻪﺑ ﻱﺪﻳﺭﻭ ﺩﺭﺩ ﺩﺎﺠﻳﺍ ﺚﻋﺎﺑ ﻪﻛ ﻱﺍ

ﻲﻣ ﻂﺳﻮﺘﻣ ﺩﻮﺷ

؛ ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﻥﻭﺪﺑ ﺐﻠﻏﺍ ﻭ ﺭﺮﻜﻣ ﺕﺭﻮﺻ ﻪﺑ

ﺶﺨﺑ ﺭﺩ ﺩﺭﺩﺪﺿ

NICU

ﻲﻣ ﻡﺎﺠﻧﺍ ﺩﻮﺷ .

ﻲﻣ ﺭﺮﻜﻣ ﻭ ﺩﺎﺣ ﻙﺎﻧﺩﺭﺩ ﺕﺎﻴﺑﺮﺠﺗ ﻭ ﻚﻳژﻮﻟﻮﻳﺰﻴﻓ ﺕﺍﺮﺛﺍ ﺪﻧﺍﻮﺗ

ﻩﺎﺗﻮﻛ ﻱﺭﺎﺘﻓﺭ ﺕﺪﻣ

)4 ( ﻲﻧﻻﻮﻃ ﺎﻳ ﻭ ﺕﺪﻣ

)5 ( ﺩﺍﺯﻮﻧ ﻱﻭﺭ ﺮﺑ

ﺩﺭﺍﺬﮕﺑ . ﺱﺎﺳﺍ ﻦﻳﺍ ﺮﺑ ،

ﺩﺭﺩ ﻝﺮﺘﻨﻛ ﺭﺩ ﻲﻤﻬﻣ ﺭﺎﻴﺴﺑ ﺶﻘﻧ

ﺩﺭﺍﺩ ﻥﺁ ﻲﻧﺍﻭﺭ ﻭ ﻲﻤﺴﺟ ﻪﺘﺳﺍﻮﺧﺎﻧ ﺕﺍﺮﺛﺍ ﺯﺍ ﻱﺮﻴﮕﺸﻴﭘ .

ﺕﺎﻜﻳﺮﺤﺗ

ﻲﻣ ﺎﻨﺷﺁ ﻲﻳﺎﻳﻮﺑ ﻲﻳﻭﺭﺍﺩﺮﻴﻏ ﺩﺭﺩ ﻝﺮﺘﻨﻛ ﺵﻭﺭ ﻚﻳ ﻥﺍﻮﻨﻋ ﻪﺑ ﺪﻧﺍﻮﺗ

ﺩﻮﺷ ﻩﺩﺎﻔﺘﺳﺍ ﻥﺍﺩﺍﺯﻮﻧ ﻂﺳﻮﺘﻣ ﺎﺗ ﻒﻴﻔﺧ ﻱﺎﻫﺩﺭﺩ ﺶﻫﺎﻛ ﺭﺩ .

ﻥﺍﺩﺍﺯﻮﻧ ﻳﺎﺑ ﺪ ﻖﻳﺮﻃ ﺯﺍ ﺪﻟﻮﺗ ﺯﺍ ﺲﭘ ﻙﻮﻧ ﺯﺍ ﻩﺪﺷﺮﺸﺘﻨﻣ ﻱﺎﻫﻮﺑ

ﺭﺩﺎﻣ ﻪﻨﻴﺳ ، ﻪﻳﺬﻐﺗ ﻊﺒﻨﻣ ﺪﻨﻨﻛ ﺍﺪﻴﭘ ﺍﺭ ﺩﻮﺧ ﻱﺍ

. ﻭﺭ ﻦﻳﺍ ﺯﺍ ، ﺲﺣ

ﻪﺑ ﺖﺒﺴﻧ ﻱﺮﺘﻬﺑ ﻞﻣﺎﻜﺗ ﺪﻟﻮﺗ ﻥﺎﻣﺯ ﺭﺩ ﺯﺎﻴﻧ ﻦﻳﺍ ﻪﺑ ﺦﺳﺎﭘ ﺭﺩ ﻲﻳﺎﻳﻮﺑ ﺲﺣ ﺮﻳﺎﺳ ﺩﺭﺍﺩ ﺎﻫ )6 ( . ﺭﺩ ﺶﻣﺍﺭﺁ ﺩﺎﺠﻳﺍ ﺭﺩ ﻲﻳﺎﻳﻮﺑ ﻢﺘﺴﻴﺳ ﺶﻘﻧ

ﻲﺳﺭﺮﺑ ﻪﻌﻟﺎﻄﻣ ﻦﻳﺪﻨﭼ ﺭﺩ ﺩﺍﺯﻮﻧ ﻩﺪﺷ ﺖﺳﺍ )7 ﻭ 8 ( . ﻦﻳﺍ ﺭﺩ

ﺕﺎﻌﻟﺎﻄﻣ ، ﻱﺭﺩﺎﻣ ﻱﺎﻫﻮﺑ ﺯﺍ ﺭﻮﻈﻨﻣ ﻪﺑ ﻣﺍﺭﺁ ﺶ ﻴﺸﺨﺑ ﻪﺑ ﻥﺪ ﺭﺩ ﺩﺍﺯﻮﻧ ﻳﺮﮔ ﻝﺎﺣ ﻪ ﺭﺩ ﺎﻫﻮﺑ ﻦﻳﺍ ﻪﻛ ﺖﺳﺍ ﻩﺪﺷ ﻩﺩﺍﺩ ﻥﺎﺸﻧ ﻭ ﻩﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ

ﻣ ﺩﺍﺯﻮﻧ ﺭﺩ ﺶﻣﺍﺭﺁ ﺩﺎﺠﻳﺍ ﺆ

ﺍ ﻩﺩﻮﺑ ﺮﺛ ﺖﺳ . ﻲﻣ ﻪﺘﻔﮔ ﺩﻮﺷ ﻪﻛ ﺕﺍﺮﺛﺍ ﺭﺁ ﻲﻣ ﻱﺭﺩﺎﻣ ﻱﺎﻫﻮﺑ ﻲﺸﺨﺒﻣﺍ ﺎﺑ ﺩﺍﺯﻮﻧ ﻥﺩﻮﺑ ﺎﻨﺷﺁ ﻞﻴﻟﺩ ﻪﺑ ﺪﻧﺍﻮﺗ

ﺪﺷﺎﺑ ﺎﻫﻮﺑ ﻦﻳﺍ .

ﺖﻋﺎﺳ ﺪﻨﭼ ﻪﻬﺟﺍﻮﻣ

ﺹﺎﺧ ﻱﻮﺑ ﻚﻳ ﺎﺑ ﺩﺍﺯﻮﻧ ﻱﺯﺎﺳ

ﻲﻣ ﺩﻮﺷ ﻮﺑ ﻥﺁ ﺎﺑ ﻱﻭ ﻥﺪﺷ ﺎﻨﺷﺁ ﺚﻋﺎﺑ ﺪﻧﺍﻮﺗ )

9 ﻭ 10 ( .

ﻪﻛ ﻲﻳﺎﻨﺷﺁ ﻱﺎﻫﻮﺑ ﺯﺍ ﺭﻮﻈﻨﻣ ﻪﺑ

ﻩﺩﺎﻔﺘﺳﺍ ﻥﺍﺩﺯﻮﻧ ﺩﺭﺩ ﻝﺮﺘﻨﻛ ﺪﺷ

ﻩ

ﺖﺳﺍ ، ﻲﻣ ﺩﺮﻛ ﻩﺭﺎﺷﺍ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﻪﺑ ﻥﺍﻮﺗ .

ﻲﻣ ﻥﺎﺸﻧ ﺕﺎﻌﻟﺎﻄﻣ ﺪﻫﺩ

ﺍ ﻪﻛ ﻲﻣ ﻪﺿﺭﺎﻋ ﻥﻭﺪﺑ ﻭ ﺪﻨﻳﺎﺷﻮﺧ ﻥﺍﺩﺍﺯﻮﻧ ﻱﺍﺮﺑ ﻮﺑ ﻦﻳ ﺪﺷﺎﺑ

)2 ﻭ

11 ( . ﻡﺎﺠﻧﺍ ﺕﺎﻌﻟﺎﻄﻣ ﺯﺍ ﻞﺻﺎﺣ ﺞﻳﺎﺘﻧ ﻪﭼ ﺮﮔﺍ ﻪﺘﻓﺎﻳ

ﻲﻣ ﻥﺎﺸﻧ ﺪﻫﺩ

ﺦﺳﺎﭘ ﺮﺑ ﻲﺑﻮﻠﻄﻣ ﺮﻴﺛﺄﺗ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﻪﻛ ﻱﺭﺎﺘﻓﺭ ﻱﺎﻫ

ﻥﺍﺩﺍﺯﻮﻧ ﺩﺭﺩ ﻪﺑ ﻁﻮﺑﺮﻣ ﻩﺪﻴﺳﺭ ﺩﺭﺍﺩ ) 2، 9 ، 10 ﻭ 12 (؛ ﻲﺗﺎﻌﻟﺎﻄﻣ ﺎﻣﺍ

ﻨﻛ ﺮﺑ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﺮﻴﺛﺄﺗ ﻲﺳﺭﺮﺑ ﻪﺑ ﻪﻛ ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ ﺩﺭﺩ ﻝﺮﺘ

ﻙﺪﻧﺍ ﺭﺎﻴﺴﺑ ﺩﺯﺍﺩﺮﭙﺑ ﺖﺳﺍ

ﻪﻨﻴﻣﺯ ﻦﻳﺍ ﺭﺩ ﻭ ،

ﻲﻣ ﻪﻌﻟﺎﻄﻣ ﻪﺑ ﻥﺍﻮﺗ

ﻡﺎﺠﻧﺍ ﻂﺳﻮﺗ ﻪﺘﻓﺎﻳ Goubet ﺭﺎﻜﻤﻫ ﻭ ﺍ ﻥ ) 2003 ( ﺩﻮﻤﻧ ﻩﺭﺎﺷﺍ .

ﺭﺩ ﺶـﻣﺍﺭﺁ ﺩﺎـﺠﻳﺍ ﻱﺍﺮـﺑ ﻞـﻴﻧﺍﻭ ﻱﺎﻨـﺷﺁ ﻱﻮـﺑ ﺯﺍ ﻪﻌﻟﺎﻄﻣ ﻦﻳﺍ ﺭﺩ ﺭﺩ ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ ﻥﻮﺧ

ﻱﺮﻴﮔ ﻩﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ ﻪﻨﺷﺎﭘ ﺵﺍﺮﺧ ﻭ ﻱﺪﻳﺭﻭ ﺖﺳﺍ

. ﺳﺩ ﻪﺑ ﺞﻳﺎﺘﻧ ﻞـﻴﻧﺍﻭ ﻱﺎﻨـﺷﺁ ﻱﻮﺑ ﺖﺒﺜﻣ ﺮﻴﺛﺄﺗ ﺮﮕﻧﺎﻴﺑ ﻩﺪﻣﺁ ﺖ

ﺦﺳﺎﭘ ﻞﻳﺪﻌﺗ ﺭﺩ ﻱﺭﺎﺘﻓﺭ ﻱﺎﻫ

ﺖـﺳﺍ ﻩﺩﻮـﺑ ﺱﺭﺎـﻧ ﻥﺍﺩﺍﺯﻮﻧ )2

( . ﺮـﺑ

ﻦﻴﺸﻴﭘ ﺕﺎﻌﻟﺎﻄﻣ ﻑﻼﺧ ،

ﺎﻄﻣ ﻦﻳﺍ ﺭﺩ ﺩﺭﺍﺪﻧﺎﺘـﺳﺍ ﺭﺍﺰﺑﺍ ﺯﺍ ﻪﻌﻟ

PIPP

ﺭﻮﻈﻨﻣ ﻪﺑ ﺖﺳﺍ ﻩﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ ﺩﺍﺯﻮﻧ ﺩﺭﺩ ﻥﺍﺰﻴﻣ ﺶﺠﻨﺳ .

ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ

ﻲﻣ ﺐﺒﺳ ﺭﻮﺑﺰﻣ ﺭﺍﺰﺑﺍ ﻪﺠﻴﺘﻧ ﺎﺗ ﺩﻮﺷ

ﻖﻴﻗﺩ ﻱﺮﻴﮔ ﺮﻴﺛﺄـﺗ ﺩﺭﻮﻣ ﺭﺩ ﻱﺮﺗ

ﺭﺩ ﺱﺭﺎـﻧ ﻥﺍﺩﺍﺯﻮـﻧ ﺩﺭﺩ ﻪﺑ ﺦﺳﺎﭘ ﺮﺑ ﻞﻴﻧﺍﻭ ﻱﺎﻨﺷﺁ ﻱﻮﺑ ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﻥﻮﺧ ﻱﺮﻴﮔ ﺪﻳﺁ ﺖﺳﺩ ﻪﺑ ﻱﺪﻳﺭﻭ .

ﻦﻴـﻴﻌﺗ ﻑﺪـﻫ ﺎـﺑ ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ

ﺯﺍ ﻲﺷﺎﻧ ﺩﺭﺩ ﻪﺑ ﺦﺳﺎﭘ ﺭﺩ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﺮﻴﺛﺄﺗ ﻥﻮﺧ

ﻱﺮـﻴﮔ ﺭﺩ ﻱﺪـﻳﺭﻭ

ﺖﺳﺍ ﻪﺘﻓﺎﻳ ﻡﺎﺠﻧﺍ ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ .

ﺵﻭﺭ ﺎﻫ

ﻲﻨﻴﻟﺎﺑ ﻲﻳﺎﻣﺯﺁﺭﺎﻛ ﻪﻌﻟﺎﻄﻣ ﻚﻳ ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ ﺪﻫﺎﺷ

ﻲﻓﺩﺎﺼﺗ ﺭﺍﺩ

؛ﺩﻮﺑ ﻪﻛ ﻝﺎﺳ ﻥﺎﺘﺴﺑﺎﺗ ﻭ ﺭﺎﻬﺑ ﺭﺩ 1392

ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ ﻱﻭﺭ ﺮﺑ

ﺭﺩ ﻱﺮﺘﺴﺑ ﺶﺨﺑ

NICU

ﻲﺷﺯﻮﻣﺁ ﺰﻛﺮﻣ ﻥﺍﺩﺍﺯﻮﻧ ﻭ

ﻲﻧﺎﻣﺭﺩ

ﺍﺮﻫﺰﻟﺍ ﺰﻳﺮﺒﺗ ﻱ ﺖﺳﺍ ﻩﺪﺷ ﻡﺎﺠﻧﺍ .

ﺭﻮﻈﻨﻣ ﻪﺑ ﻥﺍﺭﺎﻜﻤﻫ ﻭ ﻲﻨﻴﺴﺣ ﻪﻌﻟﺎﻄﻣ ﺞﻳﺎﺘﻧ ﺯﺍ ﻪﻧﻮﻤﻧ ﻢﺠﺣ ﻦﻴﻴﻌﺗ

) 1389 ( ﺪﻳﺩﺮﮔ ﻩﺩﺎﻔﺘﺳﺍ ) 9( . ﻪﻌﻟﺎﻄﻣ ﻦﻳﺍ ﺭﺩ ،

ﻉﺎﺒﺷﺍ ﺢﻄﺳ ﺕﺍﺮﻴﻴﻐﺗ

ﺪﺷ ﻪﺘﻓﺮﮔ ﺮﻈﻧ ﺭﺩ ﻪﻴﻟﻭﺍ ﺪﻣﺎﻴﭘ ﻥﺍﻮﻨﻋ ﻪﺑ ﻲﻧﺎﻳﺮﺷ ﻥﻮﺧ ﻥﮋﻴﺴﻛﺍ .

ﺎﺑ

ﻦﺘﻓﺮﮔ ﺮﻈﻧ ﺭﺩ 05 /0 ฀= ، ﻥﺍﻮﺗ 80 ﻑﻼﺘﺧﺍ ﻭ ﺪﺻﺭﺩ ﻚﻳ

ﺭﺩ ﺪﺣﺍﻭ

ﻦﻴﺑ ﺭﺩ ﻲﻧﺎﻳﺮﺷ ﻥﻮﺧ ﻥﮋﻴﺴﻛﺍ ﻉﺎﺒﺷﺍ ﺢﻄﺳ ﺕﺍﺮﻴﻴﻐﺗ ﻦﻴﮕﻧﺎﻴﻣ ﻩﻭﺮﮔ ،ﺎﻫ ﻢﺠﺣ ﺎﺑ ﺮﺑﺍﺮﺑ ﻪﻧﻮﻤﻧ ﺏﻮﻠﻄﻣ 90 ﺩﺍﺯﻮﻧ ﺪﻳﺩﺮﮔ ﺩﺭﻭﺁﺮﺑ ؛ ﻪﻛ ﺭﻮﻈﻨﻣ ﻪﺑ ﻪﻧﻮﻤﻧ ﺖﻓﺍ ﻝﺎﻤﺘﺣﺍ ﻭ ﻪﻌﻟﺎﻄﻣ ﺭﺎﺒﺘﻋﺍ ﺶﻳﺍﺰﻓﺍ ،

ﺩﺍﺪﻌﺗ 100

ﺩﺍﺯﻮﻧ ﺪﺷ ﻪﻌﻟﺎﻄﻣ ﺩﺭﺍﻭ ﻭ ﺏﺎﺨﺘﻧﺍ ﺪﻧ

ﺑ ﺰﻴﻧ ﻭ ﻪ ﻭﺩ ﺭﺩ ﻲﻓﺩﺎﺼﺗ ﺕﺭﻮﺻ

ﺪﻨﺘﻓﺮﮔ ﺭﺍﺮﻗ ﻩﻭﺮﮔ .

ﺭﺍﺩﻮﻤﻧ 1 ﺭﺩ ﻥﺎﮔﺪﻨﻨﻛ ﺖﻛﺮﺷ ﺩﺍﺪﻌﺗ ﻦﻴﻴﻌﺗ ﺪﻧﻭﺭ

ﺪﻫﺩ ﻲﻣ ﻥﺎﺸﻧ ﺍﺭ ﻪﻌﻟﺎﻄﻣ .

ﺯﺍ ﺩﻮﺑ ﺕﺭﺎﺒﻋ ﻪﻌﻟﺎﻄﻣ ﻪﺑ ﺩﻭﺭﻭ ﻂﻳﺍﺮﺷ : ﻲﮕﻠﻣﺎﺣ ﻦﺳ 32 -28 ﻔﻫ ﻪﺘ ؛

ﻚﻴﻤﺘﺴﻴﺳ ﻭ ﻱﺩﺍﺯﺭﺩﺎﻣ ﻱﺭﺎﻤﻴﺑ ﻪﺑ ﻼﺘﺑﺍ ﻡﺪﻋ ؛

ﻪﺳ ﺯﺍ ﺮﺘﺸﻴﺑ ﻦﺳ

ﺯﻭﺭ ؛ ﻥﺩﻮﺑ ﺭﺍﻮﺧﺭﺩﺎﻣﺮﻴﺷ ؛ ﻪﺑﺮﺠﺗ ﻦﺘﺷﺍﺩ ﻥﻮﺧ ﻱﺮﻴﮔ ﻱﺪﻳﺭﻭ ؛ ﺕﺎﺒﺛ ﻚﻳژﻮﻟﻮﻳﺰﻴﻓ ؛

ﻲﻨﻄﺑ ﻞﺧﺍﺩ ﻱﺰﻳﺮﻧﻮﺧ ﻡﺪﻋ ؛

ﺭﻭﺩ ﻲﺳﻻﺎﻣﻮﻜﻟ ﺎﻳ

ﻲﻨﻄﺑ ؛ ﻲﺣﺍﺮﺟ ﻝﺎﻤﻋﺍ ﻡﺎﺠﻧﺍ ﻪﺑ ﺯﺎﻴﻧ ﻡﺪﻋ ؛

ﻭ ﻱﺎﻫﻭﺭﺍﺩ ﺖﻓﺎﻳﺭﺩ ﻡﺪﻋ

،ﻮﻴﺗﺍﺪﺳ ،ﺩﺭﺩﺪﺿ ﻭﺮﺘﺳﺍﻮﻜﻴﺗﺭﻮﻛ ﻳ ﺪﻴ ﻞﺷ ﻭ ﻩﺪﻨﻨﻛ . ﺩﺭﺍﻮﻣ ﺮﺑ ﻩﻭﻼﻋ

ﺎﻳ ﻭ ﻲﻜﻴﻧﺎﻜﻣ ﻪﻳﻮﻬﺗ ﺖﺤﺗ ﺪﻳﺎﺒﻧ ﻪﻌﻟﺎﻄﻣ ﺩﺭﻮﻣ ﻥﺍﺩﺍﺯﻮﻧ ،ﻩﺪﺷ ﺮﻛﺫ ﻩﺍﺭ ﻡﻭﺍﺪﻣ ﺖﺒﺜﻣ ﺭﺎﺸﻓ ﻲﻳﺍﻮﻫ ﻱﺎﻫ

ﻲﻣ ﺪﻧﺩﻮﺑ .

ﺯﺍ ﺩﻮﺑ ﺕﺭﺎﺒﻋ ﻪﻌﻟﺎﻄﻣ ﺯﺍ ﺝﻭﺮﺧ ﻂﻳﺍﺮﺷ :

ﻲﺒﺼﻋ ﺕﻼﻜﺸﻣ ﺯﻭﺮﺑ

ﻲﻧﻼﻀﻋ ؛ ﺩﻭﺭﻭ ﻱﺎﻫﺭﺎﻴﻌﻣ ﺾﻗﺎﻧ ﻩﺪﻳﺪﭘ ﺮﻫ ﺎﻳ ﻭ ﺖﻴﻌﺿﻭ ﻱﺭﺍﺪﻳﺎﭘﺎﻧ

ﻪﻌﻟﺎﻄﻣ ﻪﺑ . ﻦﻴﻨﭽﻤﻫ ﺭﺩ ﻱﺍﺮﺑ ﺖﻴﻘﻓﻮﻣ ﻡﺪﻋ ﺕﺭﻮﺻ ﻥﻮﺧ

ﻱﺮﻴﮔ ﺎﺑ

ﺩﺪﺠﻣ ﺶﺷﻮﻛ ﻪﺑ ﺯﺎﻴﻧ ﻭ ﺖﺳﻮﭘ ﻪﺑ ﻥﺯﻮﺳ ﻥﺩﺮﻛ ﺩﺭﺍﻭ ﺭﺎﺑ ﻚﻳ ،

(3)

37

ﺭﺍﺩﻮﻤﻧ 1 : ﻪﻧﻮﻤﻧ ﺪﻨﻳﺍﺮﻓ ﻱﺮﻴﮔ

ﻪﻌﻟﺎﻄﻣ ﻪﺑ ﺩﻭﺭﻭ ﻂﻳﺍﺮﺷ ﺪﺟﺍﻭ ﻥﺍﺩﺍﺯﻮﻧ ﺖﻳﺎﺿﺭ ﺐﺴﻛ ﺯﺍ ﺲﭘ

ﺯﺍ ﻪﻧﺎﻫﺎﮔﺁ ﻦﻳﺪﻟﺍﻭ

ﻭ ﺪﻧﺪﺷ ﻪﻌﻟﺎﻄﻣ ﺩﺭﺍﻭ ﺎﺑ ﻭ ﻲﻓﺩﺎﺼﺗ ﺵﻭﺭ ﻪﺑ

ﻩﺩﺎﻔﺘﺳﺍ ﻡﺮﻧ ﺯﺍ ﺭﺍﺰﻓﺍ

Rand list

ﻙﻮﻠﺑ ﺎﺑ ﻱﺪﻨﺑ 2 ﻩﻭﺮﮔ ﻭﺩ ﻪﺑ ﻲﻳﺎﺗ

ﺪﻧﺪﺷ ﻢﻴﺴﻘﺗ ﻪﻠﺧﺍﺪﻣ ﻭ ﻝﺮﺘﻨﻛ .

ﻪﻠﺧﺍﺪﻣ ﻩﻭﺮﮔ ﻧﺍﺩﺍﺯﻮﻧ

ﺯﺍ ﻪﻛ ﺪﻧﺩﻮﺑ ﻲ

5 ﺎﺗ ﻞﺒﻗ ﻪﻘﻴﻗﺩ 30

ﺯﺍ ﺪﻌﺑ ﻪﻴﻧﺎﺛ ﻥﻮﺧ

ﻱﺮﻴﮔ ﺽﺮﻌﻣ ﺭﺩ ﻱﺪﻳﺭﻭ

ﺪﻨﺘﻓﺮﮔ ﺭﺍﺮﻗ ﻞﻴﻧﺍﻭ ﻱﺎﻨﺷﺁ ﻱﻮﺑ ﻡﺎﻤﺸﺘﺳﺍ .

ﻦﻳﺍ ﻱﺯﺎﺳﺎﻨﺷﺁ ﻩﻮﺤﻧ

ﺩﻮﺑ ﺕﺭﻮﺻ ﻦﻳﺍ ﻪﺑ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﺎﺑ ﻩﻭﺮﮔ ﻪﻛ

ﻥﺍﺩﺍﺯﻮﻧ ﻦﻳﺍ 12

-9

ﻪﻧﻮﻤﻧ ﺯﺍ ﺶﻴﭘ ﺖﻋﺎﺳ ﻪﺒﻨﭘ ﻪﻟﻮﻠﮔ ﻚﻳ ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﺎﺑ ﻱﺮﻴﮔ

ﻱﺍ

ﻪﺘﺸﻏﺁ ﻪﺑ ﻩﺪﺷ 10 ﻞﻴﻧﺍﻭ ﻩﺮﻄﻗ 64

/0 ﺪﺻﺭﺩ ﺭﻮﺗﺎﺑﻮﻜﻧﺍ ﻞﺧﺍﺩ ﺭﺩ ﻪﻛ

ﻪﻠﺻﺎﻓ ﺭﺩ ﻭ 10

ﻲﺘﻧﺎﺳ ﻥﺁ ﺮﺳ ﻱﺮﺘﻣ ﻱﻮﺑ ﺎﺑ ،ﺩﻮﺑ ﻪﺘﻓﺮﮔ ﺭﺍﺮﻗ ﺎﻫ

ﺪﻧﺪﺷ ﺎﻨﺷﺁ ﻞﻴﻧﺍﻭ .

ﻪﻛ ﺖﺳﺍ ﺮﻛﺫ ﻪﺑ ﻡﺯﻻ ﺭﻮﻈﻨﻣ ﻪﺑ

،ﺭﻮﻛﺬﻣ ﻱﻮﺑ ﻪﻴﻬﺗ ﻞﻴﻧﺍﻭ

ﻭ

ﻝﻭﺮﺴﻴﻠﮔ ﻡﺯﻻ

ﻙﺮﻣ ﻲﻧﺎﭙﻤﻛ ﺯﺍ )

Merck Chemicals,

Darmsadt, German

( ﺪﺷ ﻪﻴﻬﺗ . ﺑ ﻞﻴﻧﺍﻭ ﺯﺍ ﻲﺒﺳﺎﻨﻣ ﺭﺍﺪﻘﻣ ﻪ

ﻥﺩﺭﻮﺧ ﻢﻫ ﻝﺎﺣ ﺭﺩ ﻦﻳﺮﻴﺴﻴﻠﮔ ﻱﻭﺭ ﺮﺑ ﻲﺠﻳﺭﺪﺗ ﺕﺭﻮﺻ )

ﺭﻭﺩ

300

rpm

( ﺕﺎﻫ ﻩﺎﮕﺘﺳﺩ ﻱﻭﺭ ﺮﺑ ﺖﻴﻠﭘ

ﺭﺮﻴﺘﺳﺍ )

MR 3001 K,

Heidolph, Germany

( ﺪﺷ ﻩﺩﻭﺰﻓﺍ .

ﺑ ﻪ ﺶﻫﺎﻛ ﺭﻮﻈﻨﻣ ﻠﮔ ﻪﺘﻳﺯﻮﻜﺴﻳﻭ

ﻲﻤﻳﻼﻣ ﻱﺎﻣﺩ ،ﻞﻴﻧﺍﻭ ﻞﻣﺎﻛ ﻝﻼﺤﻧﺍ ﻭ ﻦﻳﺮﻴﺴﻴ

) C ¡ 35 -40 ( ﺪﺷ ﻝﺎﻤﻋﺍ ﻦﻳﺮﻴﺴﻴﻠﮔ ﻪﺑ .

ﺖﻳﺎﻬﻧ ﺭﺩ ، ﻑﺎﻔﺷ ﻊﻳﺎﻣ

ﻩﺪﺷ ﻞﺣ ﻞﻴﻧﺍﻭ ﻱﻭﺎﺣ ﻦﻳﺮﻴﺴﻴﻠﮔ 64

/0 ﺪﺻﺭﺩ ﻥﺪﺷ ﺩﺮﺳ ﺯﺍ ﺲﭘ

ﺑ ﻲﻨﻴﻟﺎﺑ ﻱﺎﻫﺭﺎﻛ ﻡﺎﺠﻧﺍ ﻱﺍﺮﺑ ﻩﺎﮕﺸﻳﺎﻣﺯﺁ ﻱﺎﻣﺩ ﺭﺩ ﻪ

ﺪﻣﺁ ﺖﺳﺩ .

ﻮﻧ ﻲﻟﺎﺣ ﺭﺩ ﺰﻴﻧ ﻝﺮﺘﻨﻛ ﻩﻭﺮﮔ ﻥﺍﺩﺍﺯ ﻪﺘﺸﻏﺁ ﻪﺒﻨﭘ ﻚﻳ ﻪﻛ

ﺏﺁ ﻪﺑ ﻩﺪﺷ

ﻮﺒﺳﻼﭘ ﻥﺍﻮﻨﻋ ﻪﺑ ﺮﻄﻘﻣ ﺯﺍ

5 ﺎﺗ ﻞﺒﻗ ﻪﻘﻴﻗﺩ 30

ﺯﺍ ﺪﻌﺑ ﻪﻴﻧﺎﺛ

ﻥﻮﺧ ﻱﺮﻴﮔ ﻥﺁ ﻲﻨﻴﺑ ﺮﺑﺍﺮﺑ ﺭﺩ ﺩﻮﺑ ﻪﺘﻓﺮﮔ ﺭﺍﺮﻗ ﺎﻫ

، ﺖﺤﺗ ﻥﻮﺧ ﻱﺮﻴﮔ

ﺪﻨﺘﻓﺮﮔ ﺭﺍﺮﻗ .

ﺩﺭﺩ ﻚﻳ ﻱﺍﺯﺍ ﻪﺑ ﺖﺳﺍ ﻦﻜﻤﻣ ﺩﺮﻓ ﺮﻫ ﻪﻛ ﻦﻳﺍ ﻪﺑ ﻪﺟﻮﺗ ﺎﺑ ﻪﻧﺎﺒﺷ ﻒﻠﺘﺨﻣ ﺕﺎﻋﺎﺳ ﺭﺩ ﺺﺨﺸﻣ ﺱﺎﺴﺣﺍ ﺯﻭﺭ

ﺍﺭ ﻲﺗﻭﺎﻔﺘﻣ ﻱﺎﻫ

ﻪﻧﻮﻤﻧ ؛ﺪﻨﻛ ﻪﺑﺮﺠﺗ ﻮﻧ ﻡﺎﻤﺗ ﻱﺮﻴﮔ

ﺭﺩ ﻭ ﻪﺑﺎﺸﻣ ﺖﻋﺎﺳ ﻚﻳ ﺭﺩ ﻥﺍﺩﺍﺯ

ﻲﻧﺎﻣﺯ ﻩﺯﺎﺑ 7:30

ﺎﺗ 8:30 ﺖﻓﺮﮔ ﺕﺭﻮﺻ ﺩﺍﺪﻣﺎﺑ )5

( )1 ( . ﺩﺍﺯﻮﻧ

ﻱﺍﺮﺑ ﻥﻮﺧ ﻱﺮﻴﮔ ﺮﻣﺭﺍﻭ ﻱﻭﺭ ﺮﺑ ﻥﻮﺧ

ﻱﺮﻴﮔ ﺖﺑﺎﺛ ﻱﺎﻣﺩ ﺎﺑ 37

ﻲﺘﻧﺎﺳ ﻪﺟﺭﺩ ﺭﺍﺮﻗ ﺩﺍﺮﮔ

ﺪﺷ ﻩﺩﺍﺩ . ﺭﻮﻈﻨﻣ ﻪﺑ ﺦﺳﺎﭘ ﺶﺠﻨﺳ

ﻱﺎﻫ

ﻚﻳژﻮﻟﻮﻳﺰﻴﻓ ،

ﺲﻟﺎﭘ ﻩﺎﮕﺘﺳﺩ ﻲﺴﻛﺍ

ﻩﺮﺒﻴﻟﺎﻛ ﻱﺮﺘﻣ ﻝﺪﻣ ﻩﺪﺷ

Novametrix

ﺮﺑ ﺭﺎﺸﻓ ﺩﺎﺠﻳﺍ ﻥﻭﺪﺑ ﻭ ﺐﺴﭼ ﻪﻜﺗ ﻚﻳ ﺎﺑ ﻱﻭﺭ

ﺩﺍﺯﻮﻧ ﺖﺳﺍﺭ ﻱﺎﭘ ﺖﻴﺒﺜﺗ

(4)

ﻪﻧﻮﻤﻧ ﻚﻳ ﻂﺳﻮﺗ ﻱﺮﻴﮔ ﻱﻭﺭ ﻱﺎﻫﺪﻳﺭﻭ ﻖﻳﺮﻃ ﺯﺍ ﺏﺮﺠﻣ ﺭﺎﺘﺳﺮﭘ

ﻪﻧﻮﻤﻧ ﻞﺣﺍﺮﻣ ﻡﺎﻤﺗ ﻭ ﺖﻓﺎﻳ ﻡﺎﺠﻧﺍ ﺩﺍﺭﻮﻧ ﺖﺳﺩ ﻱﺮﻴﮔ ) 30 ﻞﺒﻗ ﻪﻴﻧﺎﺛ ﻉﻭﺮﺷ ﺯﺍ ﻥﻮﺧ ﻱﺮﻴﮔ ، 30 ﻲﻳﺍﺪﺘﺑﺍ ﻪﻴﻧﺎﺛ ﻥﻮﺧ ﻱﺮﻴﮔ ﻭ 30 ﺲﭘ ﻪﻴﻧﺎﺛ

ﻡﺎﻤﺗﺍ ﺯﺍ ﻥﻮﺧ

ﻱﺮﻴﮔ ( ﻱﺭﺍﺩﺮﺒﻤﻠﻴﻓ ﻦﻴﺑﺭﻭﺩ ﻭﺩ ﻂﺳﻮﺗ

160Olympus

، ﻱﻭﺭ ﻱﺮﮕﻳﺩ ﻭ ﺩﺍﺯﻮﻧ ﺕﺭﻮﺻ ﻱﻭﺭ ﻲﻜﻳ ﻪﻛ

ﺲﻟﺎﭘ ﻲﺴﻛﺍ ﺮﺘﻣ ﺗ ﺖﻴﺒﺜ ﺪﺷ ﻂﺒﺿ ﺩﻮﺑ ﻩﺪﺷ .

ﺲﭙﺳ ﻢﻠﻴﻓ ﻂﺳﻮﺗ ﺎﻫ

ﻚﻤﻛ ﻩﺮﻤﻧ ﻭ ﺖﻳﺅﺭ ﺮﮕﺸﻫﻭﮋﭘ ﺪﺷ ﻲﻫﺩ

.

ﺭﻮﻈﻨﻣ ﻪﺑ ﺭﺍﺰﺑﺍ ﺯﺍ ﻥﺍﺩﺍﺯﻮﻧ ﺩﺭﺩ ﻥﺍﺰﻴﻣ ﻦﻴﻴﻌﺗ

PIPP

)

Premature Infant Pain Profile

( ﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ .

ﺭﺍﺰﺑﺍ ﻦﻳﺍ

ﺎﻳﺎﭘ ﻭ ﺩﺭﺍﺪﻧﺎﺘﺳﺍ ﺭﻮﻈﻨﻣ ﻪﺑ

ﻥﺍﺩﺍﺯﻮﻧ ﺭﺩ ﺩﺭﺩ ﻲﺑﺎﻳﺯﺭﺍ ﻲﻣ ﺑ ﺷﺎ ﺪ ﻭ ﻱﺍﺭﺍﺩ 7 ﺺﺧﺎﺷ ﺖﺳﺍ . ﺯﺍ 7 ﺎﺷ ،ﻪﻃﻮﺑﺮﻣ ﺺﺧ ﻪﺑ ﻁﻮﺑﺮﻣ ﺺﺧﺎﺷ ﻪﺳ

ﺦﺳﺎﭘ ﺩﺍﺯﻮﻧ ﻱﺭﺎﺘﻓﺭ ﻱﺎﻫ )

ﻭ ﻢﺸﭼ ﻥﺪﺷ ﻩﺩﺮﺸﻓ ،ﻭﺮﺑﺍ ﻥﺪﺷ ﺏﺪﺤﻣ

ﻩﺪﻨﺧ ﻂﺧ ﻝﻮﻃ ﺭﺩ ﻥﺩﺎﺘﻓﺍ ﺭﺎﻴﺷ ( ،

2 ﺦﺳﺎﭘ ﻪﺑ ﻁﻮﺑﺮﻣ ﺺﺧﺎﺷ ﻱﺎﻫ

ﻚﻳژﻮﻟﻮﻳﺰﻴﻓ )

ﻭ ﻲﻧﺎﻳﺮﺷ ﻥﻮﺧ ﻥﮋﻴﺴﻛﺍ ﻉﺎﺒﺷﺍ ﻥﺍﺰﻴﻣ ﺕﺍﺮﻴﻴﻐﺗ

ﺐﻠﻗ ﻥﺎﺑﺮﺿ ﺕﺍﺮﻴﻴﻐﺗ (

ﻭ 2 ﻪﻨﻴﻣﺯ ﺖﻴﻌﺿﻭ ﻪﺑ ﻁﻮﺑﺮﻣ ﺺﺧﺎﺷ ﻱﺍ

ﺩﺍﺯﻮﻧ ) ﻲﮕﻠﻣﺎﺣ ﻦﺳ ﻪﻳﺎﭘ ﻱﺭﺎﺘﻓﺭ ﺖﻴﻌﺿﻭ ﻭ

( ﻲﻣ ﺪﺷﺎﺑ ) 13 (. ﺹﺎﺼﺘﺧﺍ ﺯﺎﻴﺘﻣﺍ ﺺﺧﺎﺷ ﺮﻫ ﻪﺑ ﻪﺘﻓﺎﻳ

، ﻩﺮﻤﻧ ﻦﻴﺑ ﻱﺍ 0 -3 ﻲﻣ ﺪﺷﺎﺑ .

ﻲﻣ ﺩﺍﺯﻮﻧ ﺮﻫ ،ﻪﺠﻴﺘﻧ ﺭﺩ ﻩﺮﻤﻧ ﺪﻧﺍﻮﺗ ﻦﻴﺑ ﻱﺍ ﺮﻔﺻ ﺎﺗ 21 ﺪﻨﻛ ﺐﺴﻛ . ﻪﺑ ﻡﺯﻻ ﻪﻛ ﺖﺳﺍ ﺢﻴﺿﻮﺗ ﻲﺑﺎﻳﺯﺭﺍ ﺭﻮﻈﻨﻣ ﻪﺑ

ﺭﺎﺒﺘﻋﺍ ﺯﺍ ﺭﺍﺰﺑﺍ ﻲﻳﺍﻭﺭ

ﻮﺘﺤﻣ ﺍ ﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ ؛ ﺑ

ﺍ ﻪ ،ﻪﻤﺟﺮﺗ ﺯﺍ ﺲﭘ ﺭﺍﺰﺑﺍ ﻪﻛ ﺕﺭﻮﺻ ﻦﻳ ﻂﺳﻮﺗ

10 ﺎﻀﻋﺍ ﺯﺍ ﺮﻔﻧ ﻱ

ﻴﻫ ﺄ ﻠﻋ ﺕ ﻭ ﻲﻳﺎﻣﺎﻣ ﻭ ﻱﺭﺎﺘﺳﺮﭘ ﻩﺪﻜﺸﻧﺍﺩ ﻲﻤ

ﻥﺁ ﺕﺍﺮﻈﻧ ﻝﺎﻤﻋﺍ ﺯﺍ ﺲﭘ ﻭ ﻲﺳﺭﺮﺑ ﺰﻳﺮﺒﺗ ﻲﻜﺷﺰﭘ ﻩﺪﻜﺸﻧﺍﺩ ﺎﻫ

،

ﻩﺩﺎﻔﺘﺳﺍ ﺪﺷ .

،ﺭﺍﺰﺑﺍ ﻲﻳﺎﻳﺎﭘ ﻲﺑﺎﻳﺯﺭﺍ ﺭﻮﻈﻨﻣ ﻪﺑ 10

ﻭﺩ ﻂﺳﻮﺗ ﻲﻳﺍﺪﺘﺑﺍ ﻢﻠﻴﻓ

ﻚﻤﻛ ﺯﺍ ﻡﺍﺪﻛ ﺮﻫ ﻲﻓﺩﺎﺼﺗ ﺺﻴﺼﺨﺗ ﺯﺍ ﻪﻛ ﺮﮕﺸﻫﻭﮋﭘ ﻥﺍﺩﺍﺯﻮﻧ

ﻪﺑ

ﻩﻭﺮﮔ ﻲﺑﺎﻳﺯﺭﺍ ،ﺪﻨﺘﺷﺍﺪﻧ ﻲﻋﻼﻃﺍ ﻪﻃﻮﺑﺮﻣ ﻱﺎﻫ ﺪﺷ

ﺯﺎﻴﺘﻣﺍ ﻭ ﻁﻮﺑﺮﻣ

ﺪﻳﺩﺮﮔ ﻪﺒﺳﺎﺤﻣ ﺩﺍﺯﻮﻧ ﺮﻫ ﻪﺑ .

ﻦﻴﺑ ﻖﻓﺍﻮﺗ ﻲﺑﺎﻳﺯﺭﺍ ﺭﻮﻈﻨﻣ ﻪﺑ

ﻣ ﻩﺪﻫﺎﺸ ﻥﺍﺮﮔ ، ﺭﺍﺪﻘﻣ ﻭ ﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ ﻦﻫﻮﻛﺎﭘﺎﻛ ﻲﻘﻓﺍﻮﺗ ﺐﻳﺮﺿ ﺯﺍ

ﺭﻮﻛﺬﻣ ﺐﻳﺮﺿ 9/

0 ﺪﻳﺩﺮﮔ ﻪﺒﺳﺎﺤﻣ ؛

ﻥﺎﺸﻧ ﻪﻛ ﻖﻓﺍﻮﺗ ﻩﺪﻨﻫﺩ

ﻣ ﻦﻴﺑ ﺏﻮﻠﻄﻣ ﻩﺪﻫﺎﺸ

ﺑ ﻭ ﺩﻮﺑ ﻥﺍﺮﮔ ﺍ ﻪ

ﺐﻴﺗﺮﺗ ﻦﻳ ،

ﻪﻴﻘﺑ ﻲﺑﺎﻳﺯﺭﺍ

ﻧ ﻥﺍﺩﺍﺯﻮ ﻣ ﺯﺍ ﻲﻜﻳ ﻂﺳﻮﺗ ﻩﺪﻫﺎﺸ

ﻪﻣﺍﺩﺍ ﻥﺍﺮﮔ ﺖﻓﺎﻳ

.

ﻞﻴﻠﺤﺗ ﻡﺮﻧ ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﺎﺑ ﻱﺭﺎﻣﺁ ﻱﺎﻫ ﺭﺍﺰﻓﺍ SPSS ﺶﻳﺍﺮﻳﻭ 16 ﺮـﺑ ﻩﺩﺍﺩ ﻱﻭﺭ ﺖﻓﺮﮔ ﺕﺭﻮﺻ ﺮﻈﻧ ﺩﺭﻮﻣ ﻱﺎﻫ .

ﻞـﻴﻠﺤﺗ ﻭ ﻪـﻳﺰﺠﺗ ﻱﺍﺮـﺑ

ﻩﺩﺍﺩ ﺯﺍ ﺎـﻫ ﻥﻮـﻣﺯﺁ ﻱﺭﺎـﻣﺁ ﻱﺎـﻫ ﻩﺯﺍﺪـﻧﺍ ﺡﺮــﻃ ﻱﺮـﻴﮔ ﺭﺮــﻜﻣ ﻱﺎـﻫ ﻪﻠﻣﺎﻋﺪﻨﭼ ، ﻲﺗ ﻭ ﻱﺎﻛﺭﻭﺬﺠﻣ ﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ ﻞﻘﺘﺴﻣ

. ﻪـﻌﻟﺎﻄﻣ ﻦﻳﺍ ﺭﺩ ،

ﺭﺍﺪﻘﻣ 05 /0

P฀

ﻣ ﻱﺭﺎﻣﺁ ﻩﺎﮔﺪﻳﺩ ﺯﺍ ﻲﻨﻌ

ﺖﺳﺍ ﻩﺪﺷ ﻲﻘﻠﺗ ﺭﺍﺩ .

ﻪﺘﻓﺎﻳ ﺎﻫ

ﺞﻳﺎﺘﻧ ﻲﮔﮋﻳﻭ ﻪﺴﻳﺎﻘﻣ ﺯﺍ ﻞﺻﺎﺣ ﻭﺩ ﺭﺩ ﻥﺍﺩﺍﺯﻮﻧ ﻚﻴﻓﺍﺮﮔﻮﻣﺩ ﻱﺎﻫ

،ﻪﻠﺧﺍﺪﻣ ﻭ ﻝﺮﺘﻨﻛ ﻩﻭﺮﮔ ﻲﻣ ﻥﺎﺸﻧ

ﻲﻨﻌﻣ ﺕﻭﺎﻔﺗ ﻪﻛ ﺪﻫﺩ ﻦﻴﺑ ﻱﺭﺍﺩ

ﻲﮔﮋﻳﻭ ﺩﺭﺍﺪﻧ ﺩﻮﺟﻭ ﻩﻭﺮﮔ ﻭﺩ ﻥﺍﺩﺍﺯﻮﻧ ﻚﻴﻓﺍﺮﮔﻮﻣﺩ ﻱﺎﻫ )

ﻝﻭﺪﺟ 1( .

ﺕﺪﻣ ﻝﻮﻃ ﻦﻴﮕﻧﺎﻴﻣ ﻥﻮﺧ

ﻱﺮﻴﮔ ﺎﺑ ﺮﺑﺍﺮﺑ ﻞﻴﻧﺍﻭ ﻩﻭﺮﮔ ﺭﺩ

3/ 9 ± 0/ 91 ﺎﺑ ﺮﺑﺍﺮﺑ ﻝﺮﺘﻨﻛ ﻩﻭﺮﮔ ﺭﺩ ﻭ ﻪﻴﻧﺎﺛ 7/ 10 ± 4/ 89 ﻪﻴﻧﺎﺛ ﻲﻣ ﺪﺷﺎﺑ ؛ ﻪﻛ ﻲﻨﻌﻣ ﻱﺭﺎﻣﺁ ﻅﺎﺤﻟ ﺯﺍ ﺖﺴﻴﻧ ﺭﺍﺩ ) 67 /0 = P (.

ﻥﻮﻣﺯﺁ ﺞﻳﺎﺘﻧ ﺭﻭﺬﺠﻣ

ﻲﻨﻌﻣ ﻑﻼﺘﺧﺍ ﻪﻛ ﺩﺍﺩ ﻥﺎﺸﻧ ﻱﺎﻛ ﺭﺩ ﻱﺭﺍﺩ

ﻣ ﻩﻭﺮﮔ ﻭﺩ ﺭﺩ ﻪﻌﻟﺎﻄﻣ ﺩﺭﻮﻣ ﻥﺍﺩﺍﺯﻮﻧ ﻪﻳﺎﭘ ﻱﺭﺎﺘﻓﺭ ﺖﻴﻌﺿﻭ ﻩﺪﻫﺎﺸ ﻲﻤﻧ ﺩﻮﺷ ) 45 /0 = P () ﻝﻭﺪﺟ 2 .( ﺞﻳﺎﺘﻧ ﻲﺳﺭﺮﺑ ﺯﺍ ﻞﺻﺎﺣ ﺮﻤﻧ

ﻪﺒﺳﺎﺤﻣ ﺩﺭﺩ ﺕﺍ ﻩﺪﺷ

ﺮﻫ ﻥﺍﺩﺍﺯﻮﻧ ﻱﺍﺮﺑ

ﻩﻭﺮﮔ ﻭﺩ ﻥﺎﻣﺯ ﺭﺩ ﻱﺎﻫ 30 ﺯﺍ ﻞﺒﻗ ﻪﻴﻧﺎﺛ ﻥﻮﺧ ﻱﺮﻴﮔ ، 30 ﻝﻭﺍ ﻪﻴﻧﺎﺛ ﻥﻮﺧ ﻱﺮﻴﮔ ﻭ 30 ﻥﺁ ﻡﺎﻤﺗﺍ ﺯﺍ ﺲﭘ ﻪﻴﻧﺎﺛ ،

ﻪﭼﺮﮔﺍ ﻪﻛ ﺩﺍﺩ ﻥﺎﺸﻧ

ﺯﺎﻏﺁ ﺯﺍ ﺶﻴﭘ ﻥﻮﺧ

ﻱﺮﻴﮔ ، ﺎﺑ ﻪﺴﻳﺎﻘﻣ ﺭﺩ ﻪﻠﺧﺍﺪﻣ ﻩﻭﺮﮔ ﻥﺍﺩﺍﺯﻮﻧ

ﻩﺮﻤﻧ ﻦﻴﮕﻧﺎﻴﻣ ﻝﺮﺘﻨﻛ ﻩﻭﺮﮔ ﻥﺍﺩﺍﺯﻮﻧ ﻪﺘﺷﺍﺩ ﻱﺮﺘﺸﻴﺑ

ﺪﻧﺍ ؛ ﺎﻣﺍ ﻦﻴﮕﻧﺎﻴﻣ

ﻦﻴﺣ ﺭﺩ ﻪﻠﺧﺍﺪﻣ ﻩﻭﺮﮔ ﻥﺍﺩﺍﺯﻮﻧ ﺩﺭﺩ ﻩﺮﻤﻧ ﻥﻮﺧ

ﻱﺮﻴﮔ ﻡﺎﻤﺗﺍ ﺯﺍ ﺲﭘ ﻭ

ﻲﻣ ﻝﺮﺘﻨﻛ ﻩﻭﺮﮔ ﻥﺍﺩﺍﺯﻮﻧ ﺯﺍ ﺮﺘﻤﻛ ﻥﺁ ﺪﺷﺎﺑ

. ﻥﻮﻣﺯﺁ ﻡﺎﺠﻧﺍ ﻪﺘﺒﻟﺍ

ﻱﺭﺎﻣﺁ ﻲﺗ ﻲﻣ ﻥﺎﺸﻧ ﻞﻘﺘﺴﻣ ﻲﻨﻌﻣ ﺩﻮﺟﻮﻣ ﻑﻼﺘﺧﺍ ﻪﻛ ﺪﻫﺩ

ﺭﺍﺩ ﺖﺳﺍ ﻩﺩﻮﺒﻧ ) ﻝﻭﺪﺟ 3( . ﻩﺯﺍﺪﻧﺍ ﻥﻮﻣﺯﺁ ﻱﺮﻴﮔ

ﻲـﻣ ﻥﺎـﺸﻧ ﻪـﻠﻣﺎﻋﺪﻨﭼ ﺭﺮـﻜﻣ ﻱﺎـﻫ ﻪـﻛ ﺪـﻫﺩ

ﻧ ﺕﺍﺮﻴﻴﻐﺗ ﻩﻭﺮﮔ ﻞﺧﺍﺩ ﺭﺩ ﺩﺭﺩ ﻩﺮﻤ ﻥﺎﻣﺯ ﺭﺩ ﺎﻫ

ﻪـﻌﻟﺎﻄﻣ ﻒﻠﺘﺨﻣ ﻱﺎﻫ

ﻲﻨﻌﻣ ﺖﺳﺍ ﻩﺩﻮﺑ ﺭﺍﺩ ؛

ﻱﺭﻮﻃ ﻪﺑ ﻥﺎـﻣﺯ ﺭﺩ ﻪـﻛ ﻦﻴـﺣ ﻭ ﻞـﺒﻗ ﻱﺎـﻫ

ﻥﻮﺧ ﻱﺮﻴﮔ ﺯﺍ ﺲﭘ ﻭ ﻞﺒﻗ ﺰﻴﻧ ﻭ ﻥﻮﺧ ﻱﺮﻴﮔ ) 001 /0 p< ( ﻦﻴﺑ ﺭﺩ ﻭ

ﺯﺍ ﺲﭘ ﻭ ﻦﻴﺣ ﻥﺎﻣﺯ ﻭﺩ ﻥﻮﺧ ﻱﺮﻴﮔ ) 001 /0 p< ( ﻲـﻣ ﺪـﺷﺎﺑ . ﻡﺯﻻ

ﻣ ﻩﻭﺮﮔ ﻭﺩ ﻦﻴﺑ ﺭﺩ ﺕﺍﺮﻴﻴﻐﺗ ﻦﻳﺍ ﺪﻧﻭﺭ ﻪﻛ ﺖﺳﺍ ﺮﻛﺫ ﻪﺑ ﻲﻨﻌ ﻩﺩﻮﺒﻧ ﺭﺍﺩ ﺖﺳﺍ ) 8/ 0 p= ) ( ﺭﺍﺩﻮﻤﻧ 2( . ﺭﺍﺩﻮﻤﻧ 2: ﺕﺍﺮﻤﻧ ﻦﻴﮕﻧﺎﻴﻣ ﺕﺍﺮﻴﻴﻐﺗ ﻲﻨﺤﻨﻣ PIPP

(5)

39

ﻝﻭﺪﺟ 1 : ﻪﻠﺧﺍﺪﻣ ﻭ ﻝﺮﺘﻨﻛ ﻩﻭﺮﮔ ﻭﺩ ﺭﺩ ﻚﻴﻜﻔﺗ ﻪﺑ ﻪﻧﻮﻤﻧ ﻚﻴﻓﺍﺮﮔﻮﻣﺩ ﺕﺎﺼﺨﺸﻣ ﺖﻴﻌﺿﻭ

ﻚﻴﻓﺍﺮﮔﻮﻣﺩ ﻲﮔﮋﻳﻭ ﻪﻠﺧﺍﺪﻣ

ﻝﺮﺘﻨﻛ ﻥﻮﻣﺯﺁ ﻪﺠﻴﺘﻧ ﻭ ﻉﻮﻧ

ﻲﮕﻠﻣﺎﺣ ﻦﺳ )

ﻪﺘﻔﻫ ( 0/

2 ± 9/ 30 0/

(6)

ﻪﺑ ﻱﺮﺘﻤﻛ ﺶﻨﻛﺍﻭ ﻥﺍﺩﺍﺯﻮﻧ ﺮﻳﺎﺳ ﻪﺑ ﺪﻫﺩ ﻥﺎﺸﻧ ﻙﺎﻧﺩﺭﺩ ﺪﻨﻳﺍﺮﻓ

)2

ﻭ 9( .

ﺖﻠﻋ ﻲﻣ ﺭﻮﻛﺬﻣ ﺕﺎﻌﻟﺎﻄﻣ ﻭ ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ ﻦﻴﺑ ﺕﻭﺎﻔﺗ ﺭﺩ ﺪﻧﺍﻮﺗ

ﺪﺷﺎﺑ ﺩﺭﺩ ﻲﺑﺎﻳﺯﺭﺍ ﺵﻭﺭ .

ﺯﺍ ﺭﻮﻛﺬﻣ ﺕﺎﻌﻟﺎﻄﻣ ﺭﺩ ﺦﺳﺎﭘ

ﻱﺭﺎﺘﻓﺭ ﻱﺎﻫ

ﺖﺳﺍ ﻩﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ ﺩﺭﺩ ﺶﺠﻨﺳ ﻱﺍﺮﺑ .

ﻪﻛ ﻦﻳﺍ ﻪﺑ ﻪﺟﻮﺗ ﺎﺑ

ﺦﺳﺎﭘ ﻲﻣ ﺩﺍﺯﻮﻧ ﺮﻫ ﻱﺭﺎﺘﻓﺭ ﻱﺎﻫ ﺯﺍ ﻲﻌﺑﺎﺗ ﺪﻧﺍﻮﺗ

ﻭ ﻲﻨﻴﻨﺟ ﻦﺳ

ﺘﻓﺭ ﺖﻴﻌﺿﻭ ﻪﻨﻴﻣﺯ ﻱﺭﺎ

ﺏﺍﻮﺧ ﺪﻨﻧﺎﻣ ﻱﺍ ﺩﻮﻟﺁ

ﻩ ﺪﺷﺎﺑ ﻥﺩﻮﺑ ؛

ﻦﻳﺍﺮﺑﺎﻨﺑ

ﻱﺍﺮﺑ ﺱﺎﺴﺣﺍ ﺩﺭﺩ ﻥﺍﺰﻴﻣ ﺩﺭﻮﻣ ﺭﺩ ﺕﻭﺎﻀﻗ ﺮﻈﻧ ﻪﺑ ﻲﻓﺎﻛ ﻩﺪﺷ

ﻲﻤﻧ ﺪﺳﺭ . ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ ﺭﺩ ،

ﺩﺭﺍﺪﻧﺎﺘﺳﺍ ﺭﺍﺰﺑﺍ ﺯﺍ

PIPP

ﻱﺍﺮﺑ

ﺖﺳﺍ ﻩﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ ﺩﺭﺩ ﺶﺠﻨﺳ .

ﺭﺍﺰﺑﺍ ﻦﻳﺍ ﺭﺩ ،

ﺦﺳﺎﭘ ﺮﺑ ﻩﻭﻼﻋ ﻱﺎﻫ

ﺦﺳﺎﭘ ،ﻱﺭﺎﺘﻓﺭ ﻪﻨﻴﻣﺯ ﺖﻴﻌﺿﻭ ﻭ ﻚﻳژﻮﻟﻮﻳﺰﻴﻓ ﻱﺎﻫ

ﺍ ﺭﺩ ﺰﻴﻧ ﻱ

ﻲﻣ ﻞﻴﺧﺩ ﺩﺭﺩ ﺕﺪﺷ ﻪﺒﺳﺎﺤﻣ ﺪﺷﺎﺑ

.

ﺭﻮﻛﺬﻣ ﺕﺎﻌﻟﺎﻄﻣ ﺭﺩ ﻪﻛ ﺖﺳﺍ ﻦﻳﺍ ﺮﮕﻳﺩ ﻪﺟﻮﺗ ﻞﺑﺎﻗ ﻪﺘﻜﻧ ،

ﺶﻫﺎﻛ

ﺮﻛﺫ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﻲﻠﺻﺍ ﺪﻣﺎﻴﭘ ﻥﺍﻮﻨﻋ ﻪﺑ ﻪﻳﺮﮔ ﺕﺪﻣ ﻝﻮﻃ ﻲﻟﺎﺣ ﺭﺩ ﻩﺪﺷ ﻲﺑﺎﻳﺯﺭﺍ ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ ﺭﺩ ﺺﺧﺎﺷ ﻦﻳﺍ ﻪﻛ

ﻩﺪﺸﻧ

ﺖﺳﺍ . ﻲﺧﺮﺑ ﺎﺑ ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ ﺞﻳﺎﺘﻧ ﺭﺩ ﺕﻭﺎﻔﺗ ﺩﻮﺟﻭ ﻦﻳﺍﺮﺑﺎﻨﺑ ﺯﺍ

ًﻻﺎﻤﺘﺣﺍ ﻦﻴﺸﻴﭘ ﺕﺎﻌﻟﺎﻄﻣ ﺩﺭﺩ ﻲﺑﺎﻳﺯﺭﺍ ﺵﻭﺭ ﺭﺩ ﺕﻭﺎﻔﺗ ﻞﻴﻟﺩ ﻪﺑ

ﻲﻣ ﺪﺷﺎﺑ . ﻲﻣ ﺕﻭﺎﻔﺗ ﻦﻳﺍ ﺩﻮﺟﻭ ﻱﺍﺮﺑ ﻪﻛ ﻱﺮﮕﻳﺩ ﻞﻴﻟﺩ ﺩﺮﻛ ﻥﺍﻮﻨﻋ ﻥﺍﻮﺗ

،

ﻪﻬﺟﺍﻮﻣ ﻥﺎﻣﺯ ﻥﺩﻮﺑ ﺕﻭﺎﻔﺘﻣ ﻥﺎﻣﺯ ﺭﺩ ﺎﻨﺷﺁ ﻱﻮﺑ ﺎﺑ ﺩﺍﺯﻮﻧ ﻱﺯﺎﺳ

ﻡﺎﺠﻧﺍ ﻥﻮﺧ ﻱﺮﻴﮔ ﺖﺳﺍ ؛ ﻱﺭﻮﻃ ﻪﺑ ﻪﺑ ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ ﺭﺩ ﻪﻛ

ﻦﻴﺸﻴﭘ ﺕﺎﻌﻟﺎﻄﻣ ﺩﺎﻬﻨﺸﻴﭘ )

2 ﻭ 12 ( ﻪﻬﺟﺍﻮﻣ ﻉﻭﺮﺷ ، ﺎﺑ ﺩﺍﺯﻮﻧ ﻱﺯﺎﺳ

ﺯﺍ ﺎﻨﺷﺁ ﻱﻮﺑ 5

ﻉﻭﺮﺷ ﺯﺍ ﻞﺒﻗ ﻪﻘﻴﻗﺩ ﻥﻮﺧ

ﻱﺮﻴﮔ ﻪﺘﻓﺮﮔ ﺕﺭﻮﺻ

؛ﺖﺳﺍ ﻲﻟﺎﺣ ﺭﺩ ﻦﻴﺸﻴﭘ ﺕﺎﻌﻟﺎﻄﻣ ﺭﺩ ﻪﻛ

، ﻦﻳﺍ ﻪﻬﺟﺍﻮﻣ ﻱﺯﺎﺳ

ﻤﻫ ﺰ ﺕﻭﺎﻔﺗ ﻦﻳﺍ ﺪﻳﺎﺷ ﻭ ﻩﺩﻮﺑ ﺖﺳﻮﭘ ﻪﺑ ﻥﺯﻮﺳﺮﺳ ﺩﻭﺭﻭ ﺎﺑ ﻥﺎﻣ

ﺖﺳﺍ ﻪﺘﺴﻧﺍﻮﺗ ﺗ ﻪﻌﻟﺎﻄﻣ ﺞﻳﺎﺘﻧ ﺭﺩ

ﺄ ﺪﺷﺎﺑ ﺭﺍﺬﮔﺮﻴﺛ .

ﻲـﻨﻌﻣ ﺕﻭﺎﻔﺗ ﻪﻛ ﺩﺍﺩ ﻥﺎﺸﻧ ﻪﻌﻟﺎﻄﻣ ﺯﺍ ﻞﺻﺎﺣ ﺞﻳﺎﺘﻧ ﻦﻴﻨﭽﻤﻫ ﻱﺭﺍﺩ

ﺩﺭﺩ ﻩﺮﻤﻧ ﺭﺩ ﺯﺍ ﺲﭘ

ﻥﻮﺧ ﻱﺮﻴﮔ ﻩﻭﺮﮔ ﻦﻴﺑ ﺭﺩ ﺎـﻫ

ﺩﺭﺍﺪـﻧ ﺩﻮـﺟﻭ ؛

ﺭﺩ

ﻲﻟﺎﺣ ﺕﺎﻌﻟﺎﻄﻣ ﺭﺩ ﻪﻛ

Goubet

ﺍﺭﺎﻜﻤﻫ ﻭ ﻥ ) 2003 ( ﻭ

Rattaz

ﻥﺍﺭﺎﻜﻤﻫ ﻭ )

2005 ( ﺦﺳﺎﭘ ﻪـﺑ ﻞـﻴﻧﺍﻭ ﻩﻭﺮـﮔ ﻥﺍﺩﺍﺯﻮﻧ ﻱﺭﺎﺘﻓﺭ ﻱﺎﻫ

ﻲﻨﻌﻣ ﺕﺭﻮﺻ ﺖﺳﺍ ﻩﺩﻮﺑ ﻝﺮﺘﻨﻛ ﻩﻭﺮﮔ ﺯﺍ ﺮﺘﻤﻛ ﻱﺭﺍﺩ

. ﻞﻠﻋ ﺩﺭﻮﻣ ﺭﺩ ﻦﻴﻜـﺴﺗ ﻪـﻠﺣﺮﻣ ﺭﺩ ﻦﻴﺸﻴﭘ ﺕﺎﻌﻟﺎﻄﻣ ﺎﺑ ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ ﻲﻳﻮﺴﻤﻫﺎﻧ

،

ﻲﻣ ﻦﻴﺣ ﻪﻠﺣﺮﻣ ﺭﺩ ﻩﺪﺷﺮﻛﺫ ﺩﺭﺍﻮﻣ ﻪﺑ ﻥﺍﻮﺗ ﻥﻮﺧ

ﻱﺮﻴﮔ ﺩﺮﻛ ﻩﺭﺎﺷﺍ .

ﻪﺠﻴﺘﻧ ﻱﺮﻴﮔ

ﻳﺍ ﺭﺩ ﻪﻌﻟﺎﻄﻣ ﻦ ، ﺗ ﺄ ﺭﺩ ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ ﺩﺭﺩ ﻪﺑ ﺦﺳﺎﭘ ﺮﺑ ﻞﻴﻧﺍﻭ ﻱﻮﺑ ﺮﻴﺛ

ﻡﺎﮕﻨﻫ ﻥﻮﺧ ﻱﺮﻴﮔ ﺖﺳﺍ ﻩﺪﺷ ﻲﺳﺭﺮﺑ ﻱﺪﻳﺭﻭ .

ﺩﺭﺍﺪﻧﺎﺘﺳﺍ ﺭﺍﺰﺑﺍ ﺯﺍ

PIPP

ﻩﺯﺍﺪﻧﺍ ﻱﺍﺮﺑ ﻩﺪﺷ ﻩﺩﺎﻔﺘﺳﺍ ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ ﺭﺩ ﺩﺭﺩ ﻱﺮﻴﮔ

ﺖﺳﺍ . ﻲﻣ ﻥﺎﺸﻧ ﻩﺪﻣﺁ ﺖﺳﺩ ﻪﺑ ﺞﻳﺎﺘﻧ ﻱﻮﺑ ﺯﺍ ﻩﺩﺎﻔﺘﺳﺍ ﻪﻛ ﺪﻫﺩ

ﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ ﺩﺭﺩ ﻪﺑ ﺦﺳﺎﭘ ﺮﺑ ﻞﻴﻧﺍﻭ ﻱﺎﻨﺷﺁ ﻡﺎﮕﻨﻫ ﺭﺩ ﺱﺭ

ﻥﻮﺧ ﻱﺮﻴﮔ

ﺗ ﻥﺁ ﻡﺎﻤﺗﺍ ﺯﺍ ﺲﭘ ﻭ ﺄ

ﺩﺭﺍﺪﻧ ﻱﺮﻴﺛ .

ﻪﺘﺒﻟﺍ ﺭﻮﻈﻨﻣ ﻪﺑ ﻪﺠﻴﺘﻧ ﺗ ﺩﺭﻮﻣ ﺭﺩ ﻊﻃﺎﻗ ﻱﺮﻴﮔ ﺄ

ﻞﻴﻧﺍﻭ ﻱﺎﻨﺷﺁ ﻱﻮﺑ ﺮﻴﺛ

ﻦﻳﺍ ﻪﺑ ﻪﺟﻮﺗ ﺎﺑ ﻭ ﺱﺭﺎﻧ ﻥﺍﺩﺍﺯﻮﻧ ﺩﺭﺩ ﻪﺑ ﺦﺳﺎﭘ ﺮﺑ ﺮﺘﺸﻴﺑ ﻪﻛ

ﻥﺍﺩﺍﺯﻮﻧ ﻱﻭﺭ ﺮﺑ ﺕﺎﻌﻟﺎﻄﻣ ﻩﺪﻴﺳﺭ

ﺖﺳﺍ ﻩﺪﺷ ﻡﺎﺠﻧﺍ ؛

ﺩﺎﻬﻨﺸﻴﭘ

ﻲﻣ ﺩﻮﺷ ﻪﻛ ﻭ ﺮﺘﺸﻴﺑ ﻲﻠﻴﻤﻜﺗ ﺕﺎﻌﻟﺎﻄﻣ ﺍ ﺎﺑ

ﺵﻭﺭ ﺯﺍ ﻩﺩﺎﻔﺘﺳ ﻱﺎﻫ

ﺩﻮﺷ ﻡﺎﺠﻧﺍ ﻥﺍﺩﺍﺯﻮﻧ ﻦﻳﺍ ﻱﻭﺭ ﺮﺑ ﻊﻣﺎﺟ ﺩﺭﺩ ﻲﺑﺎﻳﺯﺭﺍ .

ﻥﺁ ﺯﺍ ﺎــﺟ ﻳ ﻲ ﻪــﻌﻟﺎﻄﻣ ﻚــﻳ ﺮــﺿﺎﺣ ﻪــﻌﻟﺎﻄﻣ ﻪــﻛ

Cross over

ﻲﻤﻧ ﺕﻭﺎﻔﺗ ﻭ ﺪﺷﺎﺑ ﻲﻣ ﺩﺭﺩ ﻪﺑ ﺦﺳﺎﭘ ﺭﺩ ﻱﺩﺮﻓ ﻱﺎﻫ

ﻦﻳﺍ ﺞﻳﺎﺘﻧ ﺪﻧﺍﻮﺗ

ﺗ ﺖﺤﺗ ﺍﺭ ﻪﻌﻟﺎﻄﻣ ﺄ

ﺪﻫﺩ ﺭﺍﺮﻗ ﺮﻴﺛ ؛

ﻦﻳﺍﺮﺑﺎﻨﺑ ﻲـﻣ ﺩﺎﻬﻨـﺸﻴﭘ ﺩﻮـﺷ

ﻪـﻛ

ﻪﻌﻟﺎﻄﻣ ﻩﺯﺍﺪﻧﺍ ﺵﻭﺭ ﺎﺑ ﻱﺍ ﻴﮔ

ﻱﺮ ﻪـﻨﻴﻣﺯ ﻦـﻳﺍ ﺭﺩ ﻊﻃﺎـﻘﺘﻣ ﺡﺮﻃ ﻱﺎﻫ

ﺩﻮﺷ ﻡﺎﺠﻧﺍ .

ﻲﻧﺍﺩﺭﺪﻗ ﻭ ﺮﻜﺸﺗ

ﺮﺿﺎﺣ ﻪﻌﻟﺎﻄﻣ ﺗ ﺯﺍ ﺲﭘ

ﺄ ﻡﻮﻠﻋ ﻩﺎﮕﺸﻧﺍﺩ ﻕﻼﺧﺍ ﻪﺘﻴﻤﻛ ﻂﺳﻮﺗ ﺪﻴﻳ

ﻲﻨﻴﻟﺎﺑ ﻲﻳﺎﻣﺯﺁﺭﺎﻛ ﺖﺒﺛ ﺰﻛﺮﻣ ﺭﺩ ﺖﺒﺛ ﻭ ﺰﻳﺮﺒﺗ ﻲﻜﺷﺰﭘ )

IRCT201203086918N5

( ﺖﺳﺍ ﻩﺪﺷ ﻡﺎﺠﻧﺍ .

ﻲﻣ ﺐﺟﺍﻭ ﺩﻮﺧ ﺮﺑ ﻥﺍﺮﮕﺸﻫﻭﮋﭘ ﺴﻣ ﺯﺍ ﺎﺗ ﺪﻨﻧﺍﺩ

ﺆ ،ﻥﺍﺭﺎﺘﺳﺮﭘﺮﺳ ،ﻦﻴﻟﻭ

ﺮﭘ ﻭ ﻥﺍﺭﺎﺘﺳ ﻲﻣﺎﻤﺗ ﺭﺎﻛ ﻥﺎﻨﻛ ﺶﺨﺑ ﻥﺍﺩﺍﺯﻮﻧ ﻱﺎﻫ ﻭ

NICU

ﺰﻛﺮﻣ

ﻲﺷﺯﻮﻣﺁ ú ﺪﻨﻨﻛ ﻱﺭﺍﺰﮕﺳﺎﭙﺳ ﺰﻳﺮﺒﺗ ﻱﺍﺮﻫﺰﻟﺍ ﻲﻧﺎﻣﺭﺩ .

ﺯﺍ ﻦﻴﻨﭽﻤﻫ

ﺖﻳﺎﻤﺣ ﻪﻛ ﺰﻳﺮﺒﺗ ﻲﻜﺷﺰﭘ ﻡﻮﻠﻋ ﻩﺎﮕﺸﻧﺍﺩ ﻲﺸﻫﻭﮋﭘ ﻡﺮﺘﺤﻣ ﺖﻧﻭﺎﻌﻣ ﻲﻣ ﻞﻤﻋ ﻪﺑ ﺮﻜﺸﺗ ﻝﺎﻤﻛ ﺪﻨﺘﺷﺍﺩ ﻩﺪﻬﻋ ﺮﺑ ﺍﺭ ﻪﻌﻟﺎﻄﻣ ﻦﻳﺍ ﻲﻟﺎﻣ ﺪﻳﺁ

.

ﻪﺘﻓﺎﻳ ﺯﺍ ﻪﺘﻓﺮﮔﺮﺑ ﻪﻟﺎﻘﻣ ﻦﻳﺍ ﺯﺍ ﻞﺻﺎﺣ ﻱﺎﻫ

ﻥﺎﻳﺎﭘ ﻲﻠﻴﺼﺤﺗ ﻪﻣﺎﻧ

ﻩﺎﮕﺸﻧﺍﺩ ﻲﻳﺎﻣﺎﻣ ﻭ ﻱﺭﺎﺘﺳﺮﭘ ﻩﺪﻜﺸﻧﺍﺩ ﺪﺷﺭﺍ ﻲﺳﺎﻨﺷﺭﺎﻛ ﻊﻄﻘﻣ ﻲﻣ ﺰﻳﺮﺒﺗ ﻲﻜﺷﺰﭘ ﻡﻮﻠﻋ ﺪﺷﺎﺑ

.

References

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2. Goubet N, Rattaz C, Pierrat V, Bullinger A, Lequien P. Olfactory Experience Mediates Response to Pain in Preterm Newborns. Dev Psychobiol. 2003;42(2):171-80.

3. Johnston CC, Filion F, Nuyt AM. Recorded Maternal Voice for Preterm Neonates Undergoing Heel Lance. Adv Neonatal Care. 2007;7(5):258-66.

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10. Rattaz C, Goubet N, Bullinger A. The Calming Effect of a Familiar Odor on Full-Term Newborns. J Dev Behav Pediatr. 2005;26(2):86-92.

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The Effect of Vanilla Odor on Response to Venipuncture Pain in Preterm

Newborns: a Randomized Control Clinical Trial

Mahnaz Jebreili1, Elaheh Seyyedrasouli2, Morteza Gojazade3, Mohammad Bagher Hosseini4, Hamed Hamishekar5, Hanieh Neshat Esfahlani6

1. Instructor of Nursing, Department of Pediatrics, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran

2. Instructor of Nursing, Department of Medical-Surgical Nursing, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran

3. Associate Professor of Physiology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran 4. Associate professor of Neonatology, Department of Pediatrics, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

5. Assistant Professor of Pharmacology, Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran 6. MS in Nursing, School of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran

* Corresponding author, Email: hanie.neshat@yahoo.com

Abstract

Background: Studies have shown that use of olfactory stimuli during painful medical

procedures reduces infants’ response to pain.

Aim: The main purpose of this study was investigating the effect of vanilla on pain response in preterm infants during and after venipuncture.

Methods: This study is a randomized clinical trial. Ninety preterm infants, who were randomly selected and divided into two groups of control and vanilla odor, were classified into 45 people. Infants in the vanilla group were exposed to vanilla odor from 5 minutes before and up to 30 seconds after sampling, and infants of control group were exposed to smell of distilled water. The pain score was measured using premature infant pain profile (PIPP) score 30 seconds prior, during and 30 seconds after sampling. Statistical analyses were done using SPSS 16 software. Analyses were done by t-test, chi-square and repeated measure analyses.

Results: Despite the differences between the pain scores of two groups during and after sampling, statistical analyses showed no significant differences between them (p=0.36).

Conclusion: Results of the present study showed that use of vanilla odor has no significant effect on premature infants’ pain during blood sampling.

Keywords: Vanilla odor, Pain, Venipuncture, Preterm infant

Received: 12/02/2014